Læknablaðið : fylgirit - 01.06.2009, Qupperneq 31

27TH CONGR SCAND ASSOC UROL
F Y L G I R I T 6 1
65 Lactic acid bacteria (LAB) as prophylactic aid in
recurrent bacterial cystitis
CU Skagemo1-2, K Almendingen2, A Blindheim3, PE Láhne4, GI Meling1-2
3Department of Urology and 2Faculty pivision, Akershus University Hospital,
University of Oslo, 3Department ofUrology, St. Olavs Hospital, NTNU,
Trondheim, *Department ofUrology, Vestfold Hospital, Tonsberg, Norway
carolineskagemo@gmail.com
LAB is known to reduce inflammation in IBD, to oust pathogens
during vaginitis, improve intestinal microbial balance, and in
pilot studies reduce UTI frequency.
We have designed a multi-center RCT to investigate if LAB,
orally or vaginally, reduces
- the number of UTIs and/ or
- inflammation in the urine or bladder, or improves
- QoL and/or
- immune function and stress markers
To detect a reduction of 33% in UTIs, with a significance level of
2,5% and power 80%, 120 women will be included from patients
referred to the urology departments due to recurrent UTIs.
Inclusion criteria are >3 UTIs previous year, ASA score <2, age
18-70, and no found etiology.
Subjects receive daily LAB either vaginally or orally in addition
to placebo.
Sputum, plasma, urine, bladder biopsies, questionnaires of
QoL and dietary habits are collected before and after 6 months
intervention. Monthly self-reports and urine samples are
collected.
Conclusion: This is the first RCT to address these questions.
Careful patient handling is needed for optimal patient
compliance.
66 Cannabis-induced priapism
J Bergqvist, KJ Mikines
Dept. ofUrology, Herlev Hospital, Herlev, Denmark
docjesper@me. com
Priapism is an urological emergency, usually provoked by the
injection of intracorporal vasoactive substances for the treatment
of erectile dysfunction.
This is a report of 3 separate cases of priapism, treated at the
Dept. of Urology, Herlev Hospital within a period of 8 months.
All cases were closely associated with the use of cannabis, and
none of the patients had used any other drugs, prescribed or
illegal.
This association has never previously been described
formally in the medical literature.
A plausible mechanism is discussed.
The problem is probably underreported, and more thorough
and systematic research is needed, but use of cannabis should be
considered as a triggering factor in otherwise idiopathic cases of
priapism.
LÆKNAblaðið 2009/95 31