Læknablaðið - 15.06.1984, Blaðsíða 45
LÆK.NABLADID
175
og aukaverkanaminnstu læknisþjónustu sem
völ er á hverju sinni. Notkun lidocaíns í æð
samfara inndælingu jónaðs skuggagjafa, getur
pó minnkað sjúklingum óþægindi við rann-
sókn á útlimaæðum, sé ekki annarra kosta völ.
Starfsfólki á stofu 1, Röntgendeild Landspítalans og Kjart-
ani Pálssyni hjartasérfræöingi, er pökkuð aðstoð við könn-
unina og úrlestur hjartalínurita.
SUMMARY
Iohexol, a new non-ionic low-osmolar contrast
medium, was compared to the conventional ionic
hyperosmolar contrast medium Angiografin with
Lidocain in a randomized double-blind cross-over
study of aortofemoral angiographies of 30 patients.
The patients were evaluated for signs of discomfort
and the intraarterial blood pressures, the pulse rate
and the ECG, were monitored continously. Iohexol
caused significantly less haemodynamic changes
than Angiografin with Lidocain whereas no signifi-
cant difference between the two contrast agents
was found for either pain or warmth. With the
present knowledge of the damaging effects of the
hyperosmolar contrast media on the vascular bed it
now seems advisable whenever possible and costs
permitting to replace the conventional hyperosmo-
lar contrast media by the less osmolar contrast
agents in angiography, especially in aortofemoral
angiography of ischemic legs. To reduce the incom-
fortable side-effects of the hyperosmolar contrast
media in angiography of the lower extremities, the
alternative of using Lidocain simultaneously is still
possible.
The authors are indebted to Nyegaard & Co,
Oslo, for supplying the contrast medium and proto-
cols used for this study.
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