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Læknablaðið - 01.04.1943, Side 12

Læknablaðið - 01.04.1943, Side 12
LÆKNABLAÐIÐ 116 great disadvantages of tannic acid is that its use does not avoid such damage. The tannic acid tans and harms these islands of new deli- cate epithelium. Tliey then become abnormal islands, and can not in any sense produce anything- like normal epithelium. The scar tissue that they do produce is tough, dense and fibrous, with a great tendency to contract. This is the cause of so many of the truly horrible deformities that. we have seen. This is especially true of burns involving the hands, face and genitals. You will notice that I again mention these areas se- parately. This should be stressed. Burns of these areas should and must be considered from an enti- rely different angle than, let us say, burns of the torso. Even a fairly small burn of the face, if severe, may produce a terrible contracture. The patient in whom such deformities occur faces long periods of plastic operations, many times unsuccesful, in an effort to make him • look something likc normal, and to enable him to re- sume his normal occupation. I can not stress too strongly, the psycho- logical effect of a marked defor- mity of the face.This is not only upon the patient hinself, but also upon his associates. It is difficult for such associates to look upon the patient without loathing or horror, and this is promptly felt by him, with evident result. Furthermore, in 1942, there was some experimental work done, which at least indicates that the extensive use of tannic acid may lead to liver damage. However, tannic still has its strong advocates. In an article in the Journal of Surgery, in 1942. I am again impressed by what statistics can be made to show. Casual reading of this article leads one to wonder why we have ever considered anything but tannic acid in the treatment of burn;:. However, upon closer inspection of the íigures we begin to wonder. The writers offer a set of figures' in which nine different groups of workers have tried tannic as well as ,,other methods". Note the words „other methods“. In the report, 1369 cases were treated with „other methods“, with a mortality rate of 24.5%. 1913 cases were tracted with tannic acid with an 11.3% mortality. These differ- ences are indeed striking. But, the authors then naively drew the con- clusi’on that if all of the cases had been treated with tannic, 252 fatal cases could have been saved. 1 can only cast doubts on the conclusion. Not one word wás said about a comparison of the severity of the cases in the groups, nor about what other methods were used. Unquestionaljly the tannic acid is superior to all „other methods“, but it is only fair to demand that its" use be compared to a single other method, such as triple dye, and only in cases of comparable severity. I am perfectly convinced that if the cases treated with triple dye, or cod liver oil ointment were picked out of the “other methods”, and similarly compared, the same striking difference in results would be obtained. I can only disagree with the authors conclusions as l^eing unwarranted. About eight years after David- son brought out the use of tannic acid, Robert Aldrich began using and recommending the triple dye treatment. The eschar producing substance was an aqueous solution of 1% gentian violet, 1% brilliant

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