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Læknablaðið - 01.03.2023, Blaðsíða 24

Læknablaðið - 01.03.2023, Blaðsíða 24
140 L ÆKNABL AÐIÐ 2023/109 E N G L I S H S U M M A R Y Maternal death in Iceland 1976-2015 INTRODUCTION: Maternal deaths are rare and an indirect measure of the societal framework surrounding pregnancy and childbirth. We surveyed and classified maternal mortality in Iceland using international guidelines, calculating changes over a 40-year period. MATERIAL AND METHODS: Information from Statistics Iceland on women aged 15-49 years who died in 1985- 2015 were cross-checked against birth registration and hospital admission data to identify women who died in pregnancy or ≤42 and within 43-365 days from birth or termination of a pregnancy. Data for 1976-1984 were searched manually. Case records and autopsy reports were scrutinized. Deaths were classified as direct, indirect or coincidental and as early or late. RESULTS: Among 1600 women 48 died in pregnancy or within a year after pregnancy. Births totaled 172369 and overall maternal mortality was 27.8/100.000 births. Maternal mortality by World Health Organization criteria (direct/indirect ≤42 days) occurred in 14 instances giving a maternal mortality ratio (MMR) of 8.1/100.000. Rates lowered between the first and last 10-year periods, particularly initially followed by a lesser downward trend. Direct deaths were 6, indirect 20, coincidental 22 (accidents, diseases). Causes of direct deaths were severe preeclampsia, pulmonary embolism and choriocarcinoma. Underlying causes of indirect deaths included cancer, diabetes, brain/heart conditions and suicide. No deaths occurred from ectopic pregnancy, hemorrhage or anesthesia. CONCLUSIONS: Maternal mortality in Iceland is among the lowest reported. Women died because of the pregnancy, from worsening of underlying conditions or coincidentally. Risk groups require better support. Continued attention to adverse health connected to maternity is essential. doi 10.17992/lbl.2023.03.734 dauðsföllum í þungun og innan 42ja fyrstu daganna frá lokum hennar, en heildartölur upp að einu ári breyttust minna síðustu þrjá áratugina. Þetta gerðist enda þótt konum á barneignaaldri fjölgaði talvert á sama tíma, barneignum á hverja konu fækkaði og árlegur fæðingafjöldi breyttist lítið. Þó ekki sé unnt að leggja of mikið upp úr tölfræðilegri marktækni vegna smæðar efni- viðarins og víðra frávika, tala þessar heildartölur sínu máli um Heimildir 1. Alkema L, Chou D, Hogan D, et al. United Nations Maternal Mortality Estimation Inter- Agency Group collaborators and technical advisory group. Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: A systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group. Lancet 2016; 387: 462-74. 2. Aitken RJ. The changing tide of human fertility. Hum Reprod 2022; 37: 629-38. 3. Snædal G, Biering G, Sigvaldason H. Fæðingar á Íslandi 1881-1972. Fylgirit við heilbrigð- isskýrslu 1972. Offsetmyndir SF, Reykjavík 1975: 26-31. 4. Snædal G. Maternal deaths in Iceland 1911–1975. Acta Obstet Gynecol Scand 1977; 56: 319-21. 5. Hogan MC, Foreman KJ, Naghavi M, et al. Maternal mortality for 181 countries, 1980- 2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet 2010; 375: 1609-23. 6. Rosling H, Rosling O, Rosling Rönnlund A. Factfulness. 10 grunde til at vi misforstår verden – og hvorfor den er bedre end vi tror. Lindhardt og Ringhof Forlag A/S, Kaupmannahöfn 2018. 7. World Health Organization, U.N.C. Fund, U.N.P. Division, U.N.P. & the World Bank Group. Trends in maternal mortality 2000 to 2017: estimates by WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division. Alþjóðaheilbrigðisstofnunin, Genf 2019. 8. Lawson GW, Keirse MJNC. Reflections on the Maternal Mortality Millennium Goal. Birth 2013; 40: 96-102. 9. Snædal G. Biering G, Sigvaldason H. Obstetrics and perinatal medicine in Iceland 1881-1971 with a detailed report on deliveries in Iceland 1972-1974. Acta Obstet Gynecol Scand 1975; 54: 3-47. 10. Knight M, Bunch K, Patel R, et al. Saving Lives, Improving Mothers’ Care Core Report – Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2018-20. National Perinatal Epidemiology Unit, University of Oxford 2022.WHO Fact Sheet. Maternal Mortality. 11. who.int/news-room/fact-sheets/detail/maternal-mortality - október 2022. 12. MacDorman MF, Thoma M, Declercq E, et al. Causes contributing to excess matermal mortality risk for women 35 and over, United States, 2016-2017. PLoS One 2021; 16: e0253920. 13. Colmorn LB, Petersen KB, Jakobsson M, et al. The Nordic Obstetric Surveillance Study: a study of complete uterine rupture, abnormally invasive placenta, peripartum hysterect- omy, and severe blood loss at delivery. Acta Obstet Gynecol Scand 2015; 94: 734-44. 14. Birgisdottir H, Bjarnadottir RI, Kristjansdottir K, et al. Maternal deaths in Iceland over 25 years. Acta Obstet Gynecol Scand 2016; 95: 74-8. 15. Vangen S, Bødker B, Ellingsen L, et al. Maternal deaths in the Nordic countries. Acta Obstet Gynecol Scand 2017; 96: 1112-9. 16. Halldórsdóttir ED. Mæðradauði í Skagafjarðarsýslu á 18. og 19. öld. Skagfirðingabók. Rit Sögufélags Skagfirðinga, Sauðárkróki 2019. 17. Lommerse K, Knight M, Nair M, et al. The impact of reclassifying suicides in pregnancy and in the postnatal period on maternal mortality ratios. BJOG 2019; 126: 1088-92. 18. Grunewald C, Esscher A, Lutvica A, et al. Mödradöd i Sverige: Vården hade många gån- ger kunnat vara bättre. Lärdomar från 11 års extern kollegial granskning Lakartidningen 2019: 27; 116:FPL4. 19. Haddad SM, Cecatti JG, Parpinelli MA, et al. From planning to practice: Building the national network for the surveillance of severe maternal morbidity. BMC Public Health 2011; 8; 283-92. 20. Wilmoth J, Mathers C, Say L, et al. Maternal deaths drop by one-third from 1990 to 2008: A United Nations analysis. Bull WHO 2010: 88: 718-718A. 21. Esscher A, Högberg U, Haglund B, et al. Maternal mortality in Sweden 1988-2007: more deaths than officially reported. Acta Obstet Gynecol Scand 2013; 92: 40-6. 22. Nyfløt LT, Ellingsen L, Vangen S. Hvorfor dør kvinner av graviditet i Norge i dag? Rapport maternelle dødsfall i Norge 2012-2018. Gynekologen. Medlemsblad Norsk Gynekol Foren 2021; 3: 26-27. 23. Engjom H, Aabakke AJM, Klungsøyr K, et al. COVID-19 in pregnancy-characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries. Acta Obstet Gynecol Scand 2021; 100: 1611-9. 24. Vousden N, Ramakrishnan R, Bunch K, et al. Management and implications of severe Covid-19 in pregnancy in the UK: data from the UK Obstetric Surveillance System National Cohort. Acta Obstet Gynecol Scand 2022: 101: 461-70. 25. Kallianidis A, Schutte J, Beenakkers I, et al. Confidential enquiry into maternal deaths in the Netherlands, 2006-2018. Acta Obstet Gynecol Scand 2022; 101: 441-9. 26. Deneux-Tharaux C, Morau E, Dreyfus M. 6th report on maternal deaths in France 2013- 2015, lessons learnt to improve care. J Obstet Gynecol Hum Reprod 2022; 51: 102367. 27. Hjartardóttir H. Þörf á frekari rannsóknum á útkomu þungana hjá konum af erlendum uppruna. Læknablaðið 2023: 109: 63. Greinin barst til blaðsins 21. október 2022, samþykkt til birtingar 20. febrúar 2023. markverðan árangur sem endurspeglar gæði heilbrigðisþjónustu og meðgönguverndar á Íslandi. Áskorun samtímans er að halda mæðradauða á Íslandi með því allra lægsta sem gerist. Þá þarf áfram að viðhalda sem bestu öryggi í meðgönguvernd og vinna í því hvernig þungun og eftirmál þungunar eru skráð og með- höndluð. Til þess þarf skráningar- og úrvinnslukerfi sem getur verið til fyrirmyndar. Hera Birgisdóttir1 Thor Aspelund2,3 Reynir Tómas Geirsson4,5 1The Healthcare Institution of North Iceland Sauðárkróki, 2Center for Public Health University of Iceland, 3The Icelandic Heart Association, 4Women´s Clinic, Landspitali National University Hospital, 5Faculty of Medicine, University of Iceland. Correspondence: Reynir Tómas Geirsson, reynirg@landspitali.is Key words: maternal death, maternal mortality, pregnancy, pregnancy complications, mortality, morbidity.

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