Læknablaðið : fylgirit - 01.06.1982, Page 20

8
MYOCARDIAL FUNCTION IN A POPULATION SAMPLE OF MIDDLE-AGED MEN
WITH ANGINA PECTORIS AND NORMAL OR STENOSED CORONARY ARTFRIES
M. Haqman, J. Wikstrand, I. Wallentin, D. Schlossman, K. Selin,
B. Wennerblom and L. Wilhelmsen
Section of Preventive Cardiology, Med.Clin. I, Dep. of Clin.
Physiology and Dep. of Radiology, Sahlgren's Hospital
Göteborg, Sweden
In the Primary Preventive Trial in Göteborg the prevalence
of angina pectoris was established in 8 age-cohorts of middle-
aged men. At follow-up an extensive investigation of the myo-
cardial function in cases with angina pectoris was performed
among men born in 1924-25. Twentyfive out of 4o attended
invasive as well as non-invasive investigation.
Coronary angiography revealed that 15 cases out of 25 had
normal vessels (NV) and that lo cases had significantly
stenosed vessels (SV). The frequency of hypertension was about
3o% in both groups. Resting ECG showed pathological findings
according to the Minnesota Code in 4o% in the NV group and in
3o% in the SV group. Report on dyspnoea was given in 73% in the
NV group and in 4o% in the SV group.,
Echocardiography, phonocardiography and measurements of
systolic and diastolic time intervals disclosed convincing
pathological findings to about the same degree in groups with
normal and stenosed vessels.
The results indicate that in angina pectoris signs of
myocardial dysfunction will be found both in cases with and
without coronary artery stenosis. It is also obvious that
cases with "non-arteriosclerotic angina" (Syndrome X according
to Kubler et al) is not too uncommon in the population.