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Læknablaðið - 01.05.2017, Page 16

Læknablaðið - 01.05.2017, Page 16
228 LÆKNAblaðið 2017/103 R A N N S Ó K N ENGLISH SUMMARY Introduction: The purpose of this study was to evaluate the frequency of 5 common symptoms and drug treatments prescribed and given in the last 24 hours of life in 11 medical units at Landspitali National Uni- versity Hospital of Iceland (LUH) and in 7 nursing homes (NH). Material and methods: Data was collected retrospectively from 232 charts of patients who died in 2012, using documentation in the Liver- pool Care Pathway (LCP) and the medication management system. Results: About half of the patients died at LUH with similar gender ratio but 70% of patients in NH were women. The LCP was used for 50% of all deaths at LUH and 58% in NH. In 45% of all deaths LCP was used for 24 hours or less. The most common symptoms were pain (51%), agitation (36%) and respiratory tract secretions (36%). Frequency of symptoms was similar between institutions and age groups. Cancer patients had significantly higher incidence of agitation and were prescri- bed and given higher doses of morphine compared to other groups. Regular medication for agitation was haloperidol (45%), diazepam (40%) and midazolam (5%). Close to 70% of the patients were treated with a scopolamin patch for death rattle. Conclusion: A large number of patients have symptoms in the last 24 hours of life both in hospital and in nursing homes. Symptom control can be improved by adjusting morphine doses to patients need, using regular doses of benzodiazepine for agitation and better use of anticholinergic medication for death rattle. Frequency of symptoms and drug treatment among dying patients in the last 24 hours of life at Landspitali – The National University Hospital of Iceland and in nursing homes Svandís Íris Hálfdánardóttir1, Kristín Lára Ólafsdóttir2, Valgerður Sigurðardóttir1,2,3 1Palliative Care Unit, 2Hospital based Palliative Care Consulting Team, 3Palliative Home Care Team. Key words: symptoms, medication, dying patients, last 24 hours of life, hospital, nursing homes. Correspondence: Svandís Íris Hálfdánardóttir, svaniris@landspitali.is Heimildir 1. Embætti Landlæknis. Dánarmeinaskrá. 2016. 2. Landspítali. Líknarmeðferð – leiðbeiningar um ákvörðun meðferðar og meðferðarúrræði hjá sjúklingum með lífshættulega og/eða versnandi langvinna sjúkdóma. Klínískar leiðbeiningar. 1. útgáfa desember 2009. landspitali.is/library/Sameiginlegar-skrar/Gagnasafn/ BRUNNURINN/Kliniskar-leidbeiningar/Liknarmedferd/ klin_leid_liknarmedferd_1109.pdf - febrúar 2017. 3. Ellershaw J, Wilkinson S (Eds.). Care for the Dying: A Pathway to Excellence. 2. ed. Oxford University Press, Oxford 2011. 4. Marie Curie Palliative Care Institute. National Care of the dying audit-hospitals (NCDAH). Round 3. Generic report 2011/2012. Liverpool 2012. 5. Gestsdottir B, Hjaltadottir I, Gudmannsdottir GD, Jonsson PV, Gunnarsdottir S, Sigurdardottir V. Symptoms and functional status of palliative care patients in Iceland. Br J Nurs 2015; 24: 478-83. 6. Steindal SA, Bredal IS, Sørbye LW, Lerdal A. Pain control at the end of life: a comparative study of hospitalized cancer and noncancer patients. Scand J Caring Sci 2011; 25: 771-9. 7. Drageset J, Corbett A, Selbaek G, Husebo BS. Cancer- related pain and symptoms among nursing home residents: a systematic review. J Pain Symptom Manage 2014; 48: 699-710. 8. Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manage 2006; 31: 58-69. 9. Hendriks SA, Smalbrugge M, Hertogh CMPM, van der Steen JT. Dying with dementia: symptoms, treatment, and quality of life in the last week of life. J Pain Symptom Manage 2014; 47: 710-20. 10. Lokker ME, van Zuylen L, van der Rijt CCD, van der Heide A. Prevalence, impact, and treatment of death rattle: a systematic review. J Pain Symptom Manage 2014; 47: 105-22. 11. Hui D, dos Santos R, Chisholm G, Bansal S, Souza Crovador C, Bruera E. Bedside clinical signs associated with impending death in patients with advanced cancer: Preliminary findings of a prospective, longitudinal cohort study. Cancer 2015; 121: 960-7. 12. World Health Organization. Essential Medicines in Palliative Care 2013. who.int/selection_medicines/ committees/expert/19/applications/PalliativeCare_8_A_R. pdf - febrúar 2017. 13. Klepstad P, Fladvad T, Skorpen F, Bjordal K, Caraceni A, Dale O, et al. Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients. Pain 2011; 152: 1139-45. 14. Gibbins J, McCoubrie R, Alexander N, Kinzel C, Forbes K. Diagnosing dying in the acute hospital setting – are we too late? Clin Med 2009; 9: 116-9. 15. Royal College of Physicians. National care of the dying audit for hospitals. National report. England, 2014. 16. McKeown K, Haase T, Pratschke J, Twomey S, Donovan H, Engling F. Dying in hospital in Ireland: an assessment of the quality of care in the last week of life, report 5, final synthesis report. Irish Hospice Foundation, Dublin 2010. 17. Caraceni A, Hanks G, Kaasa S, Bennett MI, Brunelli C, Cherny N, et al. Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. Lancet Oncol 2012; 13: e58-e68. 18. American Geriatrics Society Panel on the Pharmacological Management of Persistent Pain in Older P. Pharmacological Management of Persistent Pain in Older Persons. J Am Geriatr Soc 2009; 57: 1331-46. 19. Brown W. Opioid use in dying patients in hospice and hospital, with and without specialist palliative care team involvement. Eur J Cancer Care 2008; 17: 65-71. 20. Steindal SA, Bredal IS, Ranhoff AH, Sørbye LW, Lerdal A. The last three days of life: a comparison of pain management in the young old and the oldest old hospitalised patients using the Resident Assessment Instrument for Palliative Care. Int J Older People Nurs 2015; 10: 263-72. 21. Kehl Kehl KA. Caring for the patient and the family in the last hours of life. Home Health Care Manag Pract 2008; 20: 408-13. 22. Lee F-P, Leppa C, Schepp K. Using the minimum data set to determine predictors of terminal restlessness among nursing home residents. J Nurs Res 2006; 14: 286-96. 23. Lau KS, Tse DMW, Tsan Chen TW, Lam PT, Lam WM, Chan KS. Comparing noncancer and cancer deaths in Hong Kong: a retrospective review. J Pain Symptom Manage 2010; 40: 704-14. 24. National Cancer Institute (NCI). Last days of life - for health professionals. Symptoms during the final months, weeks, and days of life. 2015. https://www.cancer.gov/ about-cancer/advanced-cancer/caregivers/planning/last- -days-hp-pdq - febrúar 2017. 25. National Institute for Health and Care Excellence. NICE guideline. Care of dying adults in the last days of life. https://www.nice.org.uk/guidance/ng31 - febrúar 2017. 26. National Comprehensive Cancer Network. NCCN clinical guidelines in oncology. Palliative care. 2016. https://www. nccn.org/professionals/physician_gls/pdf/palliative.pdf - febrúar 2017. 27. Jansen K, Schaufel MA, Ruths S. Drug treatment at the end of life: An epidemiologic study in nursing homes. Scand J Prim Health Care 2014; 32: 187-92. 28. Department of Health. More care, less pathway. A review of the Liverpool Care Pathway. 2013. https://www.gov. uk/government/publications/review-of-liverpool-care- pathway-for-dying-patients - febrúar 2017. 29. Hálfdánardóttir SÍ, Sigurðardóttir V. Gæðaverkefni á Landspítala 2006-2009: Meðferðarferli fyrir deyjandi – Liverpool Care Pathway. Líknardeild í Kópavogi. 2009. 30. The International Collaborative for the Best Care of the Dying Person. Supporting Care in the Last Hours or Days of Life. mcpcil.org.uk/media/33890/international%20 model%20documentation.pdf – febrúar 2017. Þetta er engin spurning Viðbótarlífeyrir er nauðsyn Lágmarksframfærsla Lífe yris rétt ind i Vi ðb ót ar líf ey rir Allianz Ísland hf. | Dalshrauni 3 | 220 Hafnarfirði | 595 3400 | allianz@allianz.is | allianz.is Tryggir þína framtíð

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