Læknablaðið : fylgirit - 01.08.2003, Blaðsíða 49

ABSTRACTS / 27TH NORDIC PSYCHIATRIC CONGRESS I
S-XXI/5 Saturday 16/8,11:00-12:30
Psycho-educational cognitive group therapy of mixed
emotional disorders - a pilot study
Agnes Agnarsdóttir, Margrét Halldórsdóttir, Jón Friörik Sigurösson, Psychologists,
Landspítali University Hospital, Reykjavík, Iceland
j°nfsig@landspitali. is
Aim: Tlie aim of the study was to assess the effectiveness of a Psycho-
Educational Group Therapy based on Cognitive Behavioural Prin-
ciples for emotional disorders for patients attending an out-patient
clinic at the University Hospital in Reykjavik.
Method: A psycho-educational group programme, based on four
group sessions (two hours each) and homework assignments. Forty
participants diagnosed with emotional disorders (depression and
anxiety) were referred from therapists at the out-patient clinic,
psychiatrists, psychologists, nurses, and social workers.
Four psychological tests were administered at the beginning and
in the end of the treatment programme, Beck Depression Inventory
(BDI-II), Beck Hopelessness Scale (BHS), Automatic Thought
Questionnaire (ATQ), and Symptom Checklist 90-R (SCL-90-R).
Results: The main results of this pilot study will be described, mean
scores on the psychological tests and differences between those
who completed the treatment programme and patients on waiting
list. Characteristics of those who dropped out will also be described.
S-XXII/1 Saturday 17/8,11:00-12:30
Quality of life of patients with schizophrenia: A
randomized, naturalistic, controlled trial comparing
olanzapine with typical antipsychotics in Brazil
Mauricio S. I.ima. MD. Dept de psiqui, Federal University, PO Box 354, Pelotas
96015-000, Brazil. Jair de Jesus Mari, PhD, Anna MN. Costa, MD, Neusa Alexand-
rini MD, Salomao R Filho. MD, Irismar R de Oliveira, MD, Matthew Hotopf, MD.
At the conclusion of this session, the participant should be able to
demonstrate that olanzapine’s clinical profile leads to social func-
tioning and quality of life improvement superior to that achieved
with conventional treatment.
Objectives: (1) To assess the effectiveness of olanzapine for treating
schizophrenia; (2) to test the hypothesis that patients on olanzapine
have better quality of Iife than those on typical antipsychotics (APs).
Method: This was a multicenter, naturalistic, randomized, open
study that compared olanzapine with conventional APs, at hospi-
talization and during a nine-month follow-up. Outcome assessors
were blind to the allocated drug and to the objectives of the study.
Tlie daily dose of APs was determined by the doctors according to
their clinical practice routine.
Results: A total of 198 patients were randomly assigned to olanza-
pine (n=104) and typical antipsychotics (n=94). Patients on olanza-
pine showed higher improvement on PANSS negative and general
psychopathology subscales. When compared with patients on typi-
c;>l APs, patients treated with olanzapine showed higher improve-
ment in most of the SF-36 domains, with statistically significant dif-
ferences in the following domains; physical functioning, role physi-
cal, and role emotional.
Condusion: Compared with lypical antipsychotics, olanzapine has
advantages in a naturalistic setting for treating patients with schizo-
phrenia and improving relevant clinical outcomes, such as negative
symptoms and quality of life. These findings are highlighted by the
naturalistic approach adopted in this trial, as olanzapine was com-
pared with real-world practices in the use of typical APs.
References
1. Revicki DA, Namjoshi MA, Edgell ET. Health-related Quality of Life measure-
ment in Schizophrenia: a review of previous research and clinical trial results
with olanzapine treatment, in Olanzapinc (Zyprexa): A Novel Antypshychotic.
Edited by Tran PV. Bymaster FP. Tye N. Herrera JM. Breier A, Tollefson GD.
Lippincott Williams & Wilkins Healthcare, 2000.
2. Hamilton SH, Edgell ET, Revicki DA, Breier A. Functional outcomes in schizo-
phrenia: a comparison of olanzapine and haloperidol in a European sample. Int
Clin Psychopharmacol 2000; 15: 245-55.
S-XXII/2 Saturday 16/8, 11:00-12:30
TIPS study: Subjective quality of life in first episode
psychosis
Melle I, MD. PhD, Ullevaal University Hospital, 0407 Oslo, Norway. Haahr U. Friis
S, Johannesen JO. Larsen TK, Opjordsmoen S, Simonsen E, Vaglum P.
ingrid.melle@psykialri.uio.no
Background: Quality of life (QoL) is a central issue in the study of
psychotic disorders, but few studies have evaluated QoL in first
episode patients (FEP). How well do instruments developed for
chronic patients apply to FEP, how does FEP describe their subjec-
tive quality of life, and what is the relationship between subjective
QoL and clinical status in the early treatment phase?
Matcrial and mcthod: The TIPS study included consecutive FEP
from four Scandinavian health care sectors over four years. QoL
was measured with the Lehman Quality of Life Interview (L-
QoLI). At start of treatment, 282 patients completed full L-QoLI
interviews.
Results: The L-QoLI differentiated well between different sub-
groups of FEP, and in factor analyses the factor structure found in
studies of other patient populations was reproduced. There was a
low degree of association between objective and subjective QoL,
and between clinical measures and QoL. The presentation will
focus on the patients’ description of their actual living situation
(objective QoL) and perceived well being (subjective QoL), and
the relationship between subjective QoL and premorbid functio-
ning and duration of untreated psychotic illness.
S-XXII/3 Saturday 16/8, 11:00-12:30
Education on mental health is successful: A study on
adolscent's attitude towards mental health
Dóra Guórún Guðmundsdóttir, Project manager, Tlic Icelandic Mcntal Health,
Austurströnd 5,170 Seltjarnarnesi, Iceland
dora@ged.is
In the summer 2001 gave Geðrækt lectures about mental health for
adolescents. The main goal of the lectures was to inform adoles-
cents about mental health.
Aims: This study explored adolescents’ knowledge and attiludes
towards mental health, mental health problems and mental health
promotion and how their attitudes changed after the lecture.
LÆKNABLAÐIÐ / FYLGIRIT 48 2003/89 49