Læknablaðið : fylgirit - 01.08.2003, Blaðsíða 57

ABSTRACTS / 27TH NORDIC PSYCHIATRIC CONGRESS I
term outcome of anorexia nervosa with clinical onset before 18
years of age and to analyse possible outcome predictors. A total
clinical sample of restrictive type of anorexia nervosa was collected
from four clinics in northern Sweden.
Population: Of 91 patients 68 (75 %) participated in two follow-up
investigations. The mean age at onset was 14.6 years and at follow-
ups 23.5 and 30.1 years.
Methods: All patients participated in semi-structured interviews to
assess the psychosocial and medical outcome at the follow-ups. The
patients also answered EDI and SCL-90.
Results: Of the patients 85% had recovered, 11% had eating
disorder NOS, 3% anorexia nervosa and 1 % bulimia nervosa accor-
ding to DSM IV. One of the 91 patients had died (when receiving
i.v. nutrition at hospital) during the follow-up period. All the others
still lived. Various social, psychiatric, and somatic outcome results
as well as predictive factors will be presented.
Conclusion: Death rate was low and overall outcome good in this
group of adolescent onset anorexia nervosa.
S-XXVII/5 Saturday 16/8,11:00-12:30
Good outcome in adolescent onset anorexia nervosa
after systematic treatment. A follow-up study from a
Norwegian county
ínger Halvorsen. Anne Andersen, Child and Adolescent Psychiatrist/Specialist in
Clinical Nursing, BUPA, Sykehuset Buskerud HF. BUPA, Sykehusel Buskerud,
3004 Drammen, Norway. Supervisor: Sonja Heyerdahl. Research Leader.
inghalv2@frisurf.no
Background: From 1986 the Child and Adolescent Department,
Buskerud Hospital, has applied a systematic treatment of anorexia
nervosa (AN) based on close cooperation with parents and the
paediatric department. The project is a follow-up study 3,5-14,5
(mean 8,8) years after treatment start.
Aims: To study the outcome of childhood and adolescent onset
Anorexia Nervosa (AN) in a group that is representative for
patients referred to treatment. The outcome of the eating disorder
(ED), other psychiatric problems, social functioning, and life satis-
faction will be presented.
Material and Methods: Fifty-one of 55 female anorexia nervosa
patients under 18 years referred to treatment in Buskerud County
during the period 1986-1998. Mean age at treatment start 14,9 years
(±1,8), mean BMI 15,1 (±1,5). Thirty-one (61%) were hospitalised in
the paediatric ward in the acute phase of the illness. At follow-up
personal interview, measurement of weight/height/bone density and
Ruestionnaires to the former patient, parents and one ol the siblings
were used. Instruments used: EDE, EDI, MINI, Y-BOCS, S-G AF etc.
Results: Forty-two (82%) had no ED at follow-up, 1 had AN, 1 had
Bulimia Nervosa and 7 had EDNOS. There was no mortality. Atti-
tudes to eating and body weight were relaxed for 23 (61 %) and
somewhat strainful for 15 (39%) of those without ED at follow-up.
Twenty (41%) had one or more other axis-1 psychiatric diagnoses
at follow up. Depression and anxiety disorders were frequent. Only
47% were satisfied with life in general compared with 83 /o in a
Population study (HUNT). The Split-Global Assessment of Func-
tioning (S-GAF) ratings were very good (>80) for 26 (53%) on the
functioning-scale and for 19 (39%) on the symptom-scale.
Conclusions: Compared with other studies the outcome of the eat-
ing disorder was good. The frequency of other psychiatric disorders
at follow-up was similar to other studies.
S-XXVIII/1 Saturday 16/8,11:00-12:30
Neurologic disease as a risk factor for onset of
depression
Flemming Mörkeberg Nilsson MD, Senior Resident, University Hospital of Copen-
hagen, H.S Amager Hospital, Digevej 110, DK-2300 Copenhagen S, Denmark
fnm@dadlnet.dk
Objective: To investigate the temporal relationships between a
range of neurologic diseases and affective disorders.
Methods: Data derived from linkage of the Danish Psychiatric
Central Register and the Danish National Hospital Register. Seven
cohorts with neurologic index diagnoses and two control group
diagnoses were followed for up to 21 years. The incidences of affec-
tive disorders in the different groups were compared with control
groups, using competing risks to consider the risk of affective
disorder and the risk of death in the same analysis.
Rcsults: Affective disorders developed more frequently in demen-
tia, Parkinson’s disease, epilepsy, stroke, intra-cerebral haemorr-
hage, and stroke than in medically ill control groups (diabetes melli-
tus and osteoarthritis). Multiple sclerosis did not differ from the
control groups. The association was found to be strongest for
dementia and Parkinson’s disease.
Condusion: In neurologic diseases there seems to be an increased
incidence of affective disorders. The elevated incidence was fcund
especially high for dementia and Parkinson’s disease (neurode-
generative diseases).
S-XXVIII/2 Saturday 16/8, 11:00-12:30
Personality traits as predictors of first onset of
depression or mania
Muj Vinberg Chrislensen. PhD Student, Department of Psychiatry Rigshospitalet,
Blegdamsvej 9, Denmark. Lars Vedel Kessing.
maj.vinberg@rh.dk
Background: It is of interest to know whether certain personality
traits or disorders are predicting onset of the first affective episode,
for theoretical reasons and in relation to opportunities for pre-
vention and early treatment.
Aims: The personality might be altered by the affective disorder.
Therefore it is of relevance to look at longitudinal population-based
studies or at high-risk studies of subjects who have not yet deve-
loped illness and who are followed prospectively over years.
Method: A systematic review of population-based and high-risk
studies concerning personality and affective disorder in adults.
Results: There seems to be some evidence of a higher rate of the
personality traits, neuroticism and lower emotional strength in sub-
jects who subsequently will develop depressive disorder. The evi-
dence of a personality changing effect of affective episodes is sparse.
Conclusion: The casual association between personality and affec-
tjve disorder is still unclear. There is a need for well-designed longer-
term population based or high-risk studies.
LÆKNABLAÐIÐ / FYLGIRIT 48
2003/89 57