Læknablaðið : fylgirit - 01.05.1978, Page 53

Conclusion:
In children, the recommended therapeutic serum
gold levels 300 - 500 ug/100 ml are maintained
with weekly gold injections, the dose of MyocrisinR)
being about 0,7 mg/kg of body weight.
References :
1. Lorber, A., Atkins, C.J., Chang, C.C.,
Lee, Y.B., Starrs, J. and Bovy, R.A.:
Monitoring serum gold values to improve
chrysotherapy in rheumatoid arthritis.
Ann rheum Dis 32 : 133, 1973.
TABLE 1.
CORRELATION OF THE MANIFESTATION OF SIDE EFFECTS AND THE AGE OF CHILDREN AT
INITIATIOH OF CHRYSOTHERAPY
Age at the initiation of chrysotherapy No side effects Complication observed Number Per cent Total number of patients
<3 years 11 6 © 17
3-5 years 23 14 (Q 37
6-10 years 17 29 Q 46
11-15 years 8 17 Q 25
TOTAL 59 66 53 % 125
TABLE2.
AGE AT THE IHITIATION GF THE CHRYSOTHERAPY COMPLICATIOÍIS OBSERVED
Fever Headache Thrombo- cvtopenia Eosino- philia Dermatitis Haemat- uria protein- iiria
<3 years - 1 m - 1 (6.*) 3 (17.5%) 1 (6%) 2 (n%)
3-5 years - OS 1 (3%) 5 (13.5%) 1 (3%) - 9 (24%)
6-10 years - - 2 (4%) 7 (15%) 6 (13%) 6 (13%) 22 ((48%)
11-15 years 1 (4%) - 2 (8%) 1 (4%) 2 (8%) 2 (8%) 12 (S)
TOTAL 1 (0.8%) 1 (0.8%) 5 (4%) 14 (11%) 12 (10%) 9 (7%) 45 (36%)
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