Fróðskaparrit - 01.01.1965, Side 87

Fróðskaparrit - 01.01.1965, Side 87
True Hermaphroditism 95 stage. The later in foetal life the embryo is castrated, the greater the number of intersexual conditions with progressively increasing masculinization. Sex chromatin. In 1949 Barr and, Bertrarn1’ found that in female cats a chromatin body was situated at the nuclear membrane in the nerve cells, which was not the case in male individuals. Later this phenomenon was demonstrated in human cells from skin biopsies, from scrapings of the oral mucous membrane, in leucocytes, and in many different kinds of tissue sections. The phenomenon has been very valuable in the clinical examination of sexual and chromosomal developmental disturbances and abnormalities, since the cellular sex can be determined by this investigation. It is supposed that the Barr-body is formed by one single X sex chromosome, so that the number of Barr-bodies in a cell is always one below the total number of X sex chromosomes in a cell7. Actually, in certain conditions chromo-
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