Læknablaðið - 01.05.1958, Blaðsíða 3

LÆKNABLAÐIÐ
CHLwTRIDE
(Chloruthiazide)
superior to other diuretics because . . . increasing dosage
increases diuretic response
AT HIGHER DOSAGE LEVELS
Chlotride replaces parenteral mercurials
AT MEDIUM DOSAGE LEVELS
Chlotride replaces oral mercurials
AT LOWER DOSAGE LEVELS
Chlotride replaces classic carbomc
anhydrase inhibitors
fefractonness does riot develop /
nearly equimolar sodium and chloride
excretion / less potassium and bicar-
bonate excretion / metabolic acidosis
°r hypokalemia most unlikely
no evidence of toxicity / gastrointes-
tinal symptoms are rare / action vir-
tually complete within 6 to 12 hours;
patients can enjoy an uninterrupted
mgjit’s sleep
oral convemence with no sacrifice of
effectiveness / no known cóntraindi-
cations / effective even in the pres-
ence of severe cardiac, renal and
hepatic disease
more and more significant advantages than any other diuretic
MERCK SHARP & DOHME INTERNATIONAL
OIVISION OF MERCK 4 CO InC-. Í61 Avenue of the Americas. New York 13. N. Y . U. S. A.