Læknablaðið - 15.08.1989, Blaðsíða 9

LÆKNABLAÐIÐ
195
SUMMARY
CAMPYLOBACTER-PYLORI IN GASTRIC
MUCOSA
A prospective study of the prevalence of C.-pylori
in the gastric mucosa of patients with symptoms of
gastritis or ulcer.
Gastric mucosal biopsies from 37 patients, '.vho
underwent gastroscopy in the gastrointestinal
unit of the University Hospital in Iceland, were
studied. Biopsies from three different areas of the
stomach were obtained in each case. The results
of bacterial culture on Skirrow’s medium and
histological study with HE- and Warthin-Starry
staining methods were compared. C.-pylori was
found in 75.5% of the specimens and in 86.5% the
two different methods gave identical results. C,-
pylori was found more commonly in the stomach
of these icelandic patients than expected. There
was a statistically significant correlation between
the histological diagnosis of active chronic gastritis
or gastric ulcer and the presence of C.-pylori in
the mucosa. All the patients, who were found to
have gastric ulcer, and 84.8% of the patients with
chronic active gastritis had C.-pylori in the mucosa.
These results support the contention that C.-pylori
may be a causal agent in gastritis and gastric ulcer.
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