Læknablaðið : fylgirit - 01.05.1978, Page 97

2Cffo by other authors whereas we found changes in
the conducting system in 9%.
The mean age of the patients with spondylitic
heart disease was somewhat higher - 48 years -
than in the control group without cardiovascuiar
manifestations - 43 years. (Fig. 4)
Cardiovascular lesions were preferably observed
in advanced stages of the spondylitis process.
The coincidence of spondylitic heart disease
and peripheral arthritis must be pointed out. In
22% spondylitic patients with cardiac manifesta-
tions suffered from peripheral arthritis compared
with 97o of peripheral arthritis in spondylitic
patients without cardiac lesions. There was no
association of cardiac involvement to other
visceral manifestations like iritis, conjunctivitis,
urethritis or colitis.
Keferences :
1. Ansell B.M. , E.G.L. Bywaters and I.
Doniach: The aortic lesion of ankylosing
spondylitis. Brit. Heart J. 20, 507 (1958).
2. Bernstein L. and O.J. Broch: Cardiac
complications in spondylitis ankylopoetica.
Acta med. Scand. 135, 185 (1949).
3. Bulkley B.H. and W.C Roberts: Ankylosing
spondylitis and aortic regurgitation.
Description of the characteristic cardio-
vascular lesion from study of eight necropsy
patients. Circulation 48, 1014 (1973).
4. Clark W.W. , P. Kulka and W. Bauer:
Rheumatoid aortitis with aortic regurgitation,
an unusual manifestation of rheumatoid arthri-
tis (including spondylitis). Am. J. Med. 22,
580 (1957).
FREQUENCY OF CARCHOVASCULAR LESIONS IN ANKYLOSWG SPONDYLITIS
(REVIEW OF THE LITERATURE )
HEART VALVE AORTIC CONOUCTtNG
AUTHOR YEAR n DISEASE INSUFFICIENCY DISTURBANCES
n % n % n %
BERNSTEIN ond BROCH 1949 352 10 3 6 1.7
190 29 15
SCHILDER et al 1956 100 5 5 5 5 4 4
RUFFIE and FOURNIÉ 1956 150 4 2 3 2 1 0.6
BLUMBERG and RAGAN 19 56 128 6 5 4 3 1 0.7
SHARP 19 56 788 28 3 3 0.4
CLARK etal 19 57 20 20 5
GAMP and OGORREK ANSELLetol / 1958 144 8 6 5 3 6 4
WILKINSON et ol 19 58 222 4 1.8 2 0.9 2 0.9
SUTER and STEIGER 19 62 44 1 2 1 2 10 20
BACHMANN et al 1975 337 11 3.2 7 2 18 5.3
EXTRAVERTEBRAL MANIFESTATIONS IN 337 PATIENTS WITH
ANKYLOSING SPONDYLITIS
CARDIAC INVOLVEMENT
YES NO STATISTICALLY
n % n °/o SIGNIFICANT p*0j01
TOTAL 27 8 310 92
MALE 25 92 283 91
FEMALE 2 8 27 9
MEAN AGE IYEARSÍ 48 43 ♦
MEAN DURATION OF A.SP 14 14
(YEARS)
PERIPHERAL ARTHRITIS 6 22 17 5.5 ♦
IRITIS 5 18 75 24
CONJUNCTIVITIS 1 3.8 12 3.8
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