Læknablaðið - 15.11.1986, Page 31

LÆKNABLAÐIÐ
303
Ekki var teljandi munur á skjöldungum
sveinbarna og meybarna. Af þeim skjöldungum,
sem sleppt var úr við uppgjör burðarmálsbarna
skar einn sig úr hvað þyngd snerti. Hann vóg 4,5
g, var þrisvar sinnum þyngri en sá næst þyngsti í
sínum líkamsþyngdarflokki, 1500-1999 g.
Við nánari athugun kom í ljós að hér var um að
ræða fyrirburð, sem aðeins lifði eina
klukkustund, en móðirin var á lyfjameðferð
(thiouracil...?) vegna skjöldungseitrunar.
Skjöldungsþyngd fullorðinna manna. Þær
niðurstöður, sem hér koma fram í rannsókn
núverandi höfundar, leiða fyrst og fremst í ljós
allmikla stækkun skjöldungs í íslendingum á 40
árum. í körlum er stækkunin 18-21% og í konum
23-31 % eftir því hvort miðað er við alla fullorðins
aldursflokka 20-79 ára eða 20-50 ára. Hér er
núverandi rannsókn borin saman við niðurstöður
Júlíusar Sigurjónssonar, sem fyrr er getið (3).
Þannig hafa skjöldungar karla stækkað á
umræddu tímabili úr 14,45 g i 17,44 g en kvenna
úr 11,66 g í 15,28 g (31%). Niðurstöður þessar eru
fyllilega marktækar P< 0,005. Sérstaklega er
Table III. fVeight of femate thyroids in Iceland 1967-76 compared with Júl. Sigurjónsson’s studies of the thyroid
weight 1938-39.
Age in years N Weight in grams s.d. N Sigurjónsson
Min. Max Mean Weight mean s.d. Diff. %
1- 4 12 1,5 4,5 2,58 0,90 few cases
5- 9 6 3,0 6,0 4,33 1,03 3 6,17
10-14 3 5,0 8,0 7,0 1,73 4 9,88
15-19 8 7,0 16,0 12,25 3,01 12 10,72 3,75 8,3
20-29 8 9,5 21 13,44 3,60 28 11,96 4,09 12,4
30-39 11 9,0 31 18,18 7,88 27 11,71 3,62 55,0
40-49 26 7,5 22 14,62 4,46 24 10,64 3,22 37,5
50-59 33 8 33 14,82 5,40 18 12,14 4,07 22,0
60-69 77 6 30 13,87 5,56 13 10,63 4,28 30,6
70-79 67 5 33 13,54 4,49 8 10,88 4,36 24,5
80-89 37 6 30 13,23 5,96
10-19 11 5,0 16,0 10,82 3,60
20-49*) 45 7,5 31 15,28 5,52 79 11,66 3,76 31,0
20-79**) 222 5,0 33 14,25 5,45 118 11,58 3,95 23,0
*) The averages for the last two age-groups are obtained from grouping the series. **) The median in this age group: 13,62, the mode: 14,25 - 3 (14,25-13,62) = 12,66 and the mean: 14,25.
Table IV. Weights of male and female thyroid glands 1980-1983. A preliminary investigation.
Age in years Males Females
Weight in grams Weight in grams
N Min. Max Mean s.d. N Min. Max Mean s.d.
1- 4 3 1,6 4,6 2,73 0
5-9 7 3,2 12 5,73 3,40 3 3,0 10 6,58
10-14 5 6,0 12 9,60 2,61 2 5,0 n 8,05
15-19 20 8,0 26 13,95 4,76 9 10,0 24 13,89 4,65
20-29 70 8,0 35 16,90 5,97 13 9,6 30 17,95 6,61
30-39 47 6,0 35 17,95 6,33 22 3,0 38 16,63 7,53
40-49 63 8,0 35 18,88 5,59 30 5,0 35 15,00 6,42
50-59 118 7,4 35 17,27 5,40 52 7,4 30 15,78 6,47
60-69 145 8,0 36 16,33 5,42 84 8,0 32 15,47 6,70
70-79 166 6,0 34 16,00 5,17 100 7,0 35 14,23 5,99
Over 80 77 5,9 35 15,06 5,57 110 4,0 35 14,15 6,08
In this table no thyroid glands of 40 grams and over are included. The inclusion of few very samann thyroids 3,4 and 5 grams might
be disdisputeable.
It is to be noted that here the highest weights of female thyroids are now in the 20-29 years age gropus, a noticeable change.
It is also to be noted that the mean thyroid weights of females in the 20-49 years age groups are now 16,53 grams (obtained without
grouping the series), which shows more than 40 per cent enlargement since the 1938-1940 investigation, while the male thyroid
enlargment still is some 20 percent.