Læknablaðið - 01.10.2017, Blaðsíða 28

ENGLISH SUMMARY
In recent years, scientific papers have been published in Osteoporosis
International on the epidemiology of fractures in Iceland based on the
Icelandic Heart Association cohort. We report the main results with
emphasis on the major osteoporotic fractures (MOF), distal forearm,
upper arm, clinical vertebral and hip. Those four types of fractures have
been reported to cause about 90% of the total burden of all osteoporotic
fractures. The incidence of those four fractures in the Icelandic Heart
Association cohort have been used as the basis for the international
fracture risk calculator “FRAX “in Iceland. “FRAX” assesses the risk
of those fractures for the next 10 years in both sexes in the age group
40-90 years. FRAX Iceland was opened on the internet in the year 2013.
We emphasize the importance of previous fracture history as almost
40% of all major osteoporotic fractures occur after first MOF according
to our cohort. The results demonstrate the importance of time from the
first fracture as the risk of the second fracture is greater in the first two
years although increased risk remains during the next 20 years. This
indicates the importance of secondary prevention early after the first
fracture especially amongst elderly people. These results give a good
overall view about the epidemiology of fractures in Iceland in compari-
son with foreign studies and shows that age standardized incidence of
the most important osteoporotic fracture, the hip fracture, reached a
maximum around the millennium but has decreased among women until
2008 similar to what has been observed in Sweden and Denmark.
Review of epidemiology of fractures in the Icelandic Heart Association cohort
Gunnar Sigurdsson1, Kristín Siggeirsdottir1,2, Brynjolfur Y. Jonsson3, Brynjolfur Mogensen4, Elias F. Gudmundsson1, Thor Aspelund1,5, Vilmundur Gudnason1,5
1Icelandic Heart Association,2 Janus Rehabilitation,3 Lækning. 4The National University Hospital of Iceland, 5University of Iceland
Keywords: Osteoporosis, Major osteoprotic fractures, Risk assessment, FRAX Iceland.
Correspondence: Gunnar Sigurðsson, gunnars@hjarta.is
428 LÆKNAblaðið 2017/103
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