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Læknablaðið - 01.04.1969, Side 67

Læknablaðið - 01.04.1969, Side 67
New in drop form MOGADON The new way, the surer way to treat sleep disorders !• NEW. <Mogadon> possesses a new etiotropic action. in therapeutic doses it exerts a selective depressant action on the structures of the limbic system without markedly affecting •he other areas of the brain.This has the effect of screening the physio- togical mechanism which controls the °nset of sleep from disturbing emo- tional stimuli. The result: deeper sleep. Conventional hypnotics depress the entire central nervous system, felatively indiscriminantly inhibiting all areas of the brain, thus inducing a ftiniature anesthesia in the patient. 2. SURE. <Mogadon> is particularly well tolerated and possesses only minimal toxicity.The safety margin is exceptionally wide: an overdose of 100-300 mg (i.e. 20-60 times the normal therapeutic dose) which with conventional hypnotics would lead to profound coma or death merely results in a more prolonged period of deep sleep with relaxed musculature, relaxed breathing and normal cir- culation. Risk of accidental or inten- tional poisoning is therefore rcduced to an absolute minimum. 3. EFFECTIVE. As double-blind tests have confirmed, <Mogadon> has been proved to be either as good as or supcrior to the best known hypnotics of the present day in rapidity of onset, duration and depth of sleep and condition on waking up. The onset of sleep is swift but natural. The patient sleeps soundly but is readily roused. He wakes refreshed with no ‘hangover’. (Mogadon) is aTrade Mark F. Hoffmann-La Roche & Co. Ltd, Basle, Switzerland

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