Læknablaðið - 15.11.1991, Qupperneq 31

LÆKNABLAÐIÐ
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vaxandi. Rannsóknir, þar sem hægt er að bera
saman tíðni þessara sjúkdóma milli ákveðinna
árabila, gefa þetta ótvírætt til kynna.
Fjölgun innlagna á sjúkrahús, aukin
lyfjanotkun og fjölgun dauðsfalla í mörgum
löndum vegna astma benda til þess að svo sé.
Þó verður að viðurkenna að mælikvarðinn sem
notaður er við þessar rannsóknir gæti verið að
breytast.
Sú umfangsmikla könnun sem nú stendur yfir
á vegum Evrópubandalagsins gerir ekki aðeins
kleift að fá fram trúverðugan samanburð milli
landa og heimshluta, hvað varðar tíðni þessara
sjúkdóma, því grunnur er einnig lagður að
rannsóknum á hvort tíðnin breytist með því að
endurtaka könnunina að nokkrum tíma liðnum.
Fyrir okkur íslendinga er það ómetanlegt að
hafa fengið tækifæri til að taka þátt í þessu
verkefni og þeir sem hafa gert það kleift með
fjárframlögum eiga þakkir skildar.
HEIMILDIR
1. Durham SR. The significance of late responses in
asthma.Clin and Experim Allergy 1991; 21: 3-7.
2. Pepys J, Davies RJ. Allergy. Asthma. London:
Chapman and Hall, 1977: 127-8.
3. Amoldson H, Belin L, Formgren H, Lindholm B.
Asthma bronchiale. Stockholm: Almquist & Wiksell,
1970.
4. Hamburger RN. Heredity, IgE and development
of atopic allergy. Allergy unmasked. A new
understanding. Pharmacia Diagnostic 1979.
5. Blackley C. Experimental researches on the causes
and nature of catarrus aestivus. London: Bailliere and
Tindall, 1873.
6. Björkstén F, Suoniemi I, Koeki V. Neonatal birch-
pollencontact and subsequent allergy to birch pollen.
Clin Allergy 1980; 10: 581-91.
7. Korsgaard J. Mite asthma and recidency: A case-
control study on the impact of exposure to house dust
mites in dwellings. Am Rev Respir Dis 1983; 128:
231.
8. Plalt-Mills TE. Dust mite allergens and asthma. A
World-wide problem. J AUergy Clin Immunol 1989;
83: 416-27.
9. Platt-Mills TE, Pollart SM, Luczynska CM, Chapman
MD, Heymann PW. Indoor-allergens, quantification
and characterization in relation to asthma. Congress
of the European Academy of Allergology and
Clinical Immunology, Berlin 1989; Proceedings: 63-
7.
10. Björkstén F. Early allergen contacts. J Allergy Clin
Immunol 1986; 78: 1010-2.
11. Pearson DJ, Freed DLJ, Taylor G. Respiratory allergy
and month of birth. Clin Allergy 1977; 7: 29.
12. Kemp AS. Relationship between the time of birth
and the development of immediate hypersensitivity to
grass-pollen antigens. Med J Aust 1979; 1: 263-4.
13. Quoix E, Bessot JC, Kopferschmitt-Kubler MC,
Fraisse P, Pauli G. Positive skin tests to aero-
allergens and month of birth. Allergy 1988; 43: 127-
31.
14. Carosso A, Ruffino C, Bugiani M. The effect of birth
season on pollenosis. Ann Allergy 1986; 56: 300-3.
15. Morrison Smith J, Springett H. Atopic disease and
month of birth. Clin Allergy 1979; 9: 153-7.
16. Antó JM. Barcelona asthma epidemics: New
evidences two years after their control. Joint meeting
SEP-SEPCR, London sept. 9-14, 1990.
17. Frick OL, German DF, Mills J. Development
of allergy in children. I. Association with virus
infection. J Allergy Clin Immunol 1979; 63: 228-41.
18. Leibovitz E, Freihorst J, Piedra PA, Ogra PL.
Modulation of systemic and mucosal immune
responses to inhaled ragweed antigen in
experimentally induced infection with respiratory
syncytial virus. Implication in virally induced allergy.
Int Archs Allergy Appl Immunol 1988; 86: 112-6.
19. Pauwels R, Van Der Straeten M, Platteau B, Bazin
H. The non-specific enhancement of allergy. Allergy
1983; 38: 239-46.
20. Gerrard JW, Heiner DC, Ko CG, Mink J, Meyers D,
Dosman J. Immunoglobulin levels in smokers and
non-smokers. Ann Allergy 1980; 44: 261-2.
21. Burrows B, Halonen M, Barbee RA, Lebowitz MD.
The relationship of serum immunoglobulin E to
cigarette smoking. Am Rev Respir Dis 1981; 124:
523-5.
22. Warren CPW, Holford-Strevens V, Wong C, Manfred
J. The relationship between smoking and total
immunoglobulin E levels. J Allergy Clin Immunol
1982; 69: 370-5.
23. Zetterström O, Osterman K, Machado L, Johansson
SGO. Another smoking hazard: Raised serum IgE
concentration and incrised risk of occupation allergy.
Br Med J 1981; 283: 1215-7.
24. McSharry C, Wilkinson PC. Cigarette smoking
and the antibodyresponse to inhaled antigens.
Immunology Today 1986: 7; 98.
25. Weilzman M, Gortmaker S, Walker DK, Sobol A.
Matemal smoking and childhood asthma. Pediatrics
1990; 85: 505-11.
26. Murray AB, Morrison BJ. The effect of cigarette
smoke from the mother on bronchial responsiveness
and severity ofsymptoms in children with asthma. J
Allergy Clin Immunol 1985; 77: 575-81.
27. Martinez FD, Antognoni G, Macri F, et al. Parental
smoking enhanches bronchial responsiveness in nine-
year-old children. Am Rev Respir Dis 1988; 138:
518-23.
28. Tager IB. Passive smoking-bronchial responsiveness
and atopy. Editorials. Am Rev Respir Dis 1988; 138:
507-9.
29. Rantakallio P. Relationship of matemal smoking to
morbidity and mortality of the child up to the age of
five. Acta Paediatr Scand 1987; 67: 621-31.
30. Ownby DR, McCullough J. Passive exposure
to cigarette smoke does not increase allergic
sensitization in children. J Allergy Clin Immunol
1988; 82: 634-7.
31. Horwood L, Ferguson DM, Hons BA, Shannon FT.
Social and familial factors in the development and
early childhood asthma. Pediatrics 1985; 75: 859-68.
32. Andrae S, Axelsson O, Björkstén B, Fredriksson
M, Kjellman N-IM. Symptoms of bronchial
hyperreactivity and asthma in relation to
environmental factors. Arc Dis Child 1988; 63: 473-
8.