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Læknablaðið - 01.02.1969, Side 83

Læknablaðið - 01.02.1969, Side 83
New in drop form MOGADON The new way, the surer way to treat sleep disorders • ■ NEW. (Mogadoru possesses a new e<iotropic action. In therapeutic d°ses it exerts a selective depressant aetion on the structures of the limbic system without markedly afTecting <he other areas of the brain.This has •he effect of screening the physio- '°SÍcaI mechanism which controls the 0«set of sleep from disturbing emo- l<onal stimuli. The result: deeper s'eeP. Conventional hypnotics depress lhe entire central nervous system, relatively indiscriminantly inhibiting a|l areas of the brain, thus inducing a •hiniature anesthesia in the patient. 2. SURE. <Mogadon> is particularly well tolerated and possesses only minimal toxicity. The safety margin is exceptionally wide: an overdose of 100-300 mg (i.e. 20-60 times the normal therapeutic dose) which with conventional hypnotics would lead to profound coma or death merely results in a more prolonged period of deep sleep with relaxed musculature, relaxed breathing and normal gir- culation. Risk of accidental or inten- tional poisoning is therefore reduced to an absolute minimum. 3. EFFECTIVE. As double-blind tests have confirmed, <Mogadon> has been proved to be either as good as or superior to the best known hypnotics of the present day in rapidity of onset, duration and depth of sleep and condition on waking up. Thc onset of sleep is swift but nalural. The patient sleeps soundly but is readily roused. He wakes refreshed with no ‘hangover'. (Mogadon) is a Trade Mark F. Hoffmann-La Roche & Co. Ltd, Basle, Switzerland
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