Læknablaðið - 15.05.1992, Side 57

LÆKNABLAÐIÐ
211
The impaired motor function confirms findings
in earlier studies. It also corresponds with
the locomotor disabilities and handicaps.
The negative correlation of strength to
cross-section fiber area might result from
excessive use of remaining fibers leading
to a prominent hypertrophy in the weakest
subjects. Enzyme activities probably reflect
the pattern of everyday activities with little
demands on endurance. The minimal degree
of motor neuron loss in late-polio subjects
was estimated to be more than 70%, based
on calculations from electrophysiological
measurements of motor unit size, fiber size
and rnuscle strength, assuming a complete
reinnervation. The strength increase in the
resistance exercise program may be explained
by improved neural activation and the
additional muscle fiber hypertrophy, the latter,
however, not being statistically significant.
The maintenance of strength over a period of
6-12 months suggests an increase in everyday
activities playing the role of continuous
strengthening exercise. ADL disabilities and
handicaps emphasize needs for empathetic
information and improved rehabilitation
services especially conceming mobility
functions.
Key words: Late poliomyelitis, post-polio,
muscle adaptation, muscle training, EMG,
macro EMG, impairment, disability, handicap.