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Læknablaðið - 15.05.1992, Side 10

Læknablaðið - 15.05.1992, Side 10
168 LÆKNABLAÐIÐ Guðrún Þ. Hjaltadóttir, Ásgeir Kristjánsson, Eyjólfur Harðarson og Margrét Magnúsdóttir fá einnig þakkir höfunda fyrir veitta aðstoð. SUMMARY Primary prevention of coronary ris'k factors among factory workers - a cohort study of two years dietary intervention. High cholesterol is considered to be a major risk factor for coronary heart diseases (CHD). Although new drugs may be effective in lowering serum cholesterol, diet with low fat content and rich in fibres is still the comerstone for therapy of hyperlipidemia. Dietary intervention studies have mostly been carried out by using dietary advise, group sessions and informative brochures for those persons who are considered at »high risk«. However it seems difficult for most people to change their life style and the result of these efforts has often been disappointing. The aim of this study was to assess the effect of workplace oriented dietary intervention on CHD risk factors especially cholesterol, in ferroalloy factory workers in Grundartangi, in westem Iceland. The two hundred workers have at least one hot meal per day while working, provided by the factory kitchen.The GP’s at Akranes Health Center are responsible for the health care of the workers. A nutritionist held three meetings with the study subjects including one where spouses were invited. In cooperation with the workers and the cook, the nutritionist changed the ingredients of the kitchen menu by lowering the total amount of calories, minimizing fat, especially saturated. 155 workers (thereof 20 women) were then followed- up for two years with regard to serum lipids, smoking, weight, dietary habits and exercise. The study subjects were divided into four groups according to initial cholesterol value. The two groups with highest levels, >7.0 mmol/1 (35% of all) got more interventive attention than the others. The mean serum cholesterol levels in the whole group decreased from 6.6 mmol/1 to 6.1 or 7.6% (p<0.001) after two years. Favourable changes also occured in high density lipoprotein (HDL) which increased significantly and the ratio ol' LDL/HDL and cholesterol/HDL decreased significantly during the follow-up period. No statistical changes occurred in body mass index (BMI), exercise or smoking habits. It is concluded that this relatively simple workplace oriented dietary intervention for two years was found to significantly alter blood lipids in a favourable manner and if continued should decrease the future risk of CHD amongst the employees. HEIMILDIR 1. The Pooling Project Research Group. Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events; final report of Pooling Project. J Chron Dis 1978; 31: 201-306. 2. Hjermann I, Holme I, Velve BK, Leren P. Effect of diet and smoking intervention on the incidence of coronary heart disease. Lancet 1981; 2: 1303-10. 3. The Lipid Research Clinics Coronary Primary Prevention Trials. I. Reduction in incidcnce of coronary heart disease. JAMA 1984; 251: 351-64. 4. Puska P, Tuomilehto J, Salonen J, et al. Changes in coronary risk factors during comprehensive five- year community programme to control cardiovascular diseases (North Karelia project). Br Med J 1979; 2: 1173-8. 5. Turpeinen O, Karvonen MJ, Pekkarinen M, Miettinen M, Elosuo R. Paavilainen E. Dietary prevention of coronary heart disease: The Finnish Mental Hospital Study. lnt J Epidemiol 1979; 8: 99-118. 6. Neaton JD. Broste S, Cohen L, Fishman EL, Kjelsberg MO, Schoenberger J. The multiple risk factor intervention trial (MRFIT); VII. A comparison of risk factor changes between the two study groups. Prev Med 1981; 10: 519-43. 7. Steingrímsdóttir L, Sigurðsson G. Matarráðgjöf við hækkuðu serum kólesteróli. Læknablaðið 1983; 69: 126-8. 8. Guðrún Þóra Hjaltadóttir. Úttekt á fæði í Grundartanga 1989-90 (handrit). 9. Olafsdóttir E, Guðmundsson ÞV. Samanburður á blóðfitumælingum átta íslenskra rannsóknastofa. Læknablaðið 1990; 76: 307-11. 10. Samráðsnefnd landlæknisembættisins. Meðferð við hárri blóðfitu. Læknablaðið 1991; 77: 59-60. 11. WHO European collaborative group. Multifactorial trial in the prevention of coronary heart disease: 1. Recruitment and initial findinas. Eur Heart J 1980; 1: 73-80. 12. WHO European collaborative group. Multifactorial trial in the prevention of coronary heart disease: 2. Risk factor changes at two and four years. Eur Heart J 1982; 3: 184-90. 13. Rose G, Heller RF, Pedoe HT, Christie DGS. Heart disease prevention project: a randomised controlled trial in industry. Br Med J 1980; 281: 747-80. 14. Komitser M, De Backer G, Dramaix M, Thilly C. The Belgian heart disease prevention project. Modification of the coronary risk profile in an industrial population. Circulation 1980; 61: 18-25. 15. Björkelund C. The Strömstad survey. A model for prevention of cerebrovascular and cardiovascular disease in women within the primary health care organisation. Gothenburg: University of Gothenburg, 1990: 25. (Doktorsritgerð). 16. Stamler J, Wentworth D, Neaton JD, et al. Is relationship betwecn serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356.222 primary screenees of the multiple risk factor intervention trial (MRFIT). JAMA 1986; 256: 2823-8. 17. Castelli WP, Garrison RJ. Wilson PWF, et al. Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham study. JAMA 1986; 256: 2835-8. 18. Björkelund C, Bengtsson C. Feasibility of a primary health care programme aiming at reducing cardiovascular and cerebrovascular risk factors

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