Læknablaðið - 15.05.1992, Qupperneq 38

194
LÆKNABLAÐIÐ
Fullorðnir með sjúkdóm Menetrier hafa auk
þess aukna tíðni annarra sjúkdóma svo sem
hjarta- og æðasjúkdóma og alvarlegra eða
endurtekinna sýkinga.
Hvað varðar einkenni og horfur er nánast um
tvo ólíka sjúkdóma að ræða hjá börnum og
fullorðnum. Til þessa hefur þó þótt rétt að
líta á þetta sem einn og sama sjúkdóminn
hvað varðar samsvarandi röntgenmyndir,
magaspeglun og vefjabreytingar. Sjúkdómur
Menetrier er enn kenndur við manninn, sem
fyrstur lýsti þessu fyrirbæri fyrir meira en
einni öld.
Þrátt fyrir að þetta teljist fremur sjaldgæfur
sjúkdómur hjá bömum, þótti rétt að minna á
tilvist hans með skrifum þessum. Þar með má
bæta honum í mismunargreiningarsafn okkar,
hvað varðar bjúg og blóðprótínlækkun hjá
börnum.
SUMMARY
A 21/2 year old boy with Menetrier’s disease
is described. Clinical symptoms included
fatique, loss of appetite and peripheral edema.
Hypoalbuminaemia without proteinuria was present.
These findings abated within 2 weeks and X-ray
changes (hypertrophy of gastric mucosa) within
3 months. Different presentation and prognosis
of Menetrier’s disease in children versus adults is
discussed.
HEIMILDIR
1. Menetrier P. Des polyadénomes gastriques et de leurs
rapports avec le cancer de l’estomac. Arch Physiol
Norm Pathol 1888; 32: 236-62.
2. Citrin Y, Sterling K, Halsted JA. The mechanism of
hypoproteinemia associated with giant hypertrophy of
the gastric mucosa. N Engl J Med 1957; 257: 906-12.
3. Scharschmidt BF. The natural history of hypertrophic
gastropathy (Menetrier’s disease). Report of a case
with 16 year follow-up and review of 120 cases from
the literature. Am J Med 1977; 63: 644-52.
4. Searcy RM, Malagelada JR. Ménétrier’s disease and
idiopathic hypertrophic gastropathy. Ann Intem Med
1984; 100: 565-70.
5. Pittman FE, Harris RC, Barker HG. Transient edema
and hypoproteinemia. Possible Menetrier’s disease.
Am J Dis Child 1964; 108: 189-97.
6. Schuster W. Clinical and roentgenological signs of
giant hypertrophic gastritis in childhood (Ménétrier’s
disease). Ann Radiol (Paris) 1967; 10: 221-5.
7. Herskovic T, Spiro HM, Gryboski JD. Acute
transient gastrointestinal protein loss. Pediatrics 1968;
41: 818-21.
8. Lachman RS, Martin DJ, Vawter GF. Thick gastric
folds in childhood. AJR 1971; 112: 83-92.
9. Sandberg DH. Hypertrophic gastropathy (Menetrier’s
disease) in childhood. J Pediatr 1971; 78: 866-8.
10. Leonides JC, Beatty EC, Wenner HA. Ménétrier
disease and cytomegalovirus infection in childhood.
Am J Dis Child 1973; 126: 806-8.
11. Gwinn JL, Lee FA. Radiolgical case of the month.
Am J Dis Child 1976; 130: 419-20.
12. Newman CL, McClure JP, Bentley JFR. Case report.
Menetrier’s syndrom in children. Acta Paediatr Scand
1976; 65: 753-5.
13. Burrell M, Avella J, Gryboski J, Ablow R. Transient
hypertrophic gastropathy in childhood: a protein-
losing gastropathy distinct from Menetrier’s disease.
Am J Gastroenterol 1979; 72: 458-64.
14. Floret D, Renaud H, Hage G, Aymard M, Monnet
P. Gastrite avec hypoproteinemie chez l’enfant.
Rapport avec la maladie de Menetrier et la maladie
des inclusions cytomegaliques. Aréh Fr Pediatr 1978;
35: 82-9. ,
15. Buts JP, Harmant G, DeMayer R. La gastropathie
hypertrophique et exsudative de l’enfant. Arch Fr
Pediatr 1978; 35: 845-53.
16. Henderson SE, Spraque PL. A case of hypertrophic
protein losing gastropathy. Pediatr Radiol 1979; 8:
261-2.
17. Kraut JR, Powell R, Hruby MA, Lloyd-Still JD.
Menetrier’s disease in childhood: report of two cases
and a review of the literature. J Pediatr Surg 1981;
16: 707-11.
18. Chouraqui JP, Roy CC, Brochu P, Gregoire H, Morin
CL, Weber AM. Ménétrier’s disease in children:
report of a patient and review of sixteen other cases.
Gastroenterology 1981; 80: 1042-7.
19. Stillman AE, Sieber O, Manthei U, Pinnas J.
Transient protein-losing enteropathy and enlarged
gastric mgae in childhood. Am J Dis Child 1981;
135: 29-33.
20. Coad NAG, Shah KJ. Menetrier’s disease in
childhood associated with cytomegalovims infection:
a case report and review of the literature. Br J Radiol
1986; 59: 615-20.
21. Baker A, Volberg F, Sumner T, Moran R. Childhood
Menetrier’s disease: four new cases and discussion of
the literature. Gastrointest Radiol 1986; 11: 131-4.
22. Larsen B, Tarp U, Kristensen E. Familial giant
hypertrophic gastritis (Ménétrier’s disease). Gut
1987; 28: 1517-21.
23. Day DL, Allan BT, Young LW. Radiological case of
the month. Am J Dis Child 1988; 142: 91-2.
24. Bar-Ziv J, Barki Y, Weizman Z, Urkin J. Transient
protein-losing gastropathy (Menetrier’s disease) in
childhood. Pediatr Radiol 1988; 18 : 82-4.
25. Raic F, Votava A, Tambic L, Manojlovic S. Case
report: hypertrophic gastritis in association with
sepsis and death in a two-month-old infant. J Pediatr
Gastroenterol Nutr 1988; 7: 461-5.
26. Kawakami E, da Cmz AS, Patricio FR, Medeiros
EH, Wehba J, Fagundes Neto U. Doenca de
Ménétrier na crianca: relato de trés casos e revisao
da literatura. Arq Gastroenterol 1990; 27: 33-40.
27. Gassner I, Strasser K, Bart G, Maurer H.
Sonographic appearance of Ménétrier’s disease in a
child. J Ultrasound Med 1990; 9: 537-9.
28. Oderda G, Cinti S, Cangiotti AM, Fomi M, Ansaldi
N. Increased tight junction width in two children
with Ménétrier’s disease. J Pediatr Gastroenterol Nutr
1990; 11: 123-7.
29. Roussel M, Dupont C, Sidibe T, Andre C, Barbet P,
Badoual J. Gastrite hypertrophique bénigne associée
á une infection á cytomégalovirus. Arch Fr Pediatr
1990; 47: 271-3.