Læknablaðið - 15.11.2010, Qupperneq 32

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The effect of maternal weight on pregnancy outcome
Objective: To examine the frequency of adverse outcome
during pregnanoy and delivery and neonatal complications
among normal weight, overweight and obese women at the
beginning of pregnancy.
Material and methods: The study is a retrospective cohort
study of 600 women, divided in 3 groups on the basis
of maternal body mass index (BMI) at the beginning of
pregnancy; 300 normal weight women (BM119.0-24.9), 150
overweight women (BMI 25.0-29.9) and 150 obese women
(BMI&30). Maternal and neonatal complications were
compared between groups.
Results: Obese women have a significantly increased risk
of; essential hypertension prior to pregnancy (p<0.001),
developing gestational hypertension (p=0.03), pre-
eclampsia (p=0.007), gestational diabetes (p<0.001),
musculoskeletal symptoms (p=0.04), requiring induction of
labour (p=0.006) and being delivered by cesarean section
(p<0.001), both emergent (p=0.012) and elective (p=0.008)
compared to mothers of normal weight and overweight.
Neonates of obese mothers have significantly higher birth
weight (p=0.004), larger head circumference (p<0.001)
and are more likely to require admission to neonatal ward
compared with neonates of normal weight and overweight
mothers (p=0.004).
Conclusions: Obesity carries a significant risk to
maternal and neonatal health. During pregnancy maternal
complications are increased causing adverse effects for
both mother and infant. Women of reproductive age need
counselling regarding the adverse effects of obesity on
pregnancy outcome.
Eliasdottir OJ, Hardardottir H, Thorkelsson Th.
The effect of maternal weight on pregnancy outcome. Icel Med J 2010; 96: 691-6
Key words: pregnancy, delivery, overweight, obesity, neonate.
Correspondence: Hildur Harðardóttir, hhard@iandspitaii.is
696 LÆKNAblaðið 2010/96
Barst: 12. mars 2010, - samþykkt til birtingar: 14. september 2010
Hagsmunatengsl: Engin