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Læknablaðið - 15.09.2012, Síða 23

Læknablaðið - 15.09.2012, Síða 23
RANNSÓKN Heimildir 1. Jónasson J, Tryggvadóttir L. Krabbamein á íslandi - Upplýsingar úr Krabbameinsskrá fyrir tímabilið 1957- 2006. Krabbameinsfélagið, Reykjavík 2008. 2. Brjóstakrabbamein, vefur Krabbameinsskrár. vvww. krabbameinsskra.is - október 2011. 3. Autier P, Boniol M, LaVecchia C, Vatten L, Gavin A, Héry C, et al. Disparities in breast cancer mortality trends between 30 European countries: retrospective trend ana- lysis of WHO mortality database. BMJ 2010; 341: c3620- c3620. 4. Al-Ghazal SK, Fallowfield L, Blamey RW. Comparison of psychological aspects and patient satisfaction following breast conserving surgery, simple mastectomy and breast reconstruction. Eur J Cancer 2000; 36:1938-43. 5. Elder EE, Brandberg Y, Björklund T, Rylander R, Lager- gren J, Jurell G, et al. Quality of life and patient satis- faction in breast cancer patients after immediate breast reconstruction: a prospective study. Breast 2005; 14:201-8. 6. Rowland JH, Desmond KA, Meyerowitz BE, Belin TR, Wyatt GE, Ganz PA. Role of breast reconstructive surgery in physical and emotional outcomes among breast cancer survivors. J Natl Cancer Inst 2000; 92:1422-9. 7. Cordeiro PG. Breast reconstruction after surgery for breast cancer. N Engl J Med 2008; 359:1590-1601. 8. Woerdeman LAE, Hage JJ, Smeulders MJC, Rutgers EJT, van der Horst CMAM. Skin-sparing mastectomy and immediate breast reconstruction by use of implants: an assessment of risk factors for complications and cancer control in 120 patients. Plast Reconstr Surg 2006; 118: 321- 30; discussion 331-2. 9. Medina-Franco H, Vasconez LO, Fix RJ, Heslin MJ, Beenken SW, Bland KI, et al. Factors associated with local recurrence after skin-sparing mastectomy and immediate breast reconstruction for invasive breast cancer. Ann Surg 2002; 235: 814-9. 10. Vandeweyer E, Hertens D, Nogaret JM, Deraemaecker R. Immediate breast reconstruction with saline-filled implants: no interference with the oncologic outcome? Plast Reconstr Surg 2001; 107:1409-12. 11. Murphy RX Jr, Wahhab S, Rovito PF, Harper G, Kimmel SR, Kleinman LC, et al. Impact of immediate reconstruction on the local recurrence of breast cancer after mastectomy. Ann Plast Surg 2003; 50: 333-8. 12. Al-Ghazal SK, Sully L, Fallowfield L, Blamey RW. The psychological impact of immediate rather than delayed breast reconstruction. Eur J Surg Oncol 2000; 26:17-9. 13. Jeevan R, Cromwell D, Browne J, Meulen J, Pereira J, Caddy C, et al. Third Annual Report of the National Mastectomy and Breast Reconstruction Audit. 2010. www. ic.nhs.uk/mbr - október 2011. 14. Jeevan R, Cromwell D, Browne J, Meulen J, Pereira J, Caddy C, et al. Second Annual Report of the National Mastectomy and Breast Reconstruction Audit. 2009. www. ic.nhs.uk/mbr - október 2011. 15. Chevray PM. Timing of breast reconstruction: immediate versus delayed. Cancer J 2008; 14:223-9. 16. Goodwin SJ, McCarthy CM, Pusic AL, Bui D, Howard M, Disa JJ, et al. Complications in smokers after postmastectomy tissue expander/implant breast recon- struction. Ann Plast Surg 2005; 55:16-9; discussion 19-20. 17. Behranwala KA, Dua RS, Ross GM, Ward A, A'hern R, Gui GPH. The influence of radiotherapy on capsule formation and aesthetic outcome after immediate breast reconstruction using biodimensional anatomical expander implants. J Plast Reconstr Aesthet Surg 2006; 59:1043-51. 18. Cordeiro PG, Pusic AL, Disa JJ, McCormick B, VanZee K. Irradiation after immediate tissue expander/implant breast reconstruction: outcomes, complications, aesthetic results, and satisfaction among 156 patients. Plast Reconstr Surg 2004; 113: 877-81. 19. Spear SL, Maxwell GP. Reconstruction and the radiated breast: is there a role for implants? Plast Reconstr Surg 1995; 96:1116-8. 20. McKeown DJ, Hogg FJ, Brown IM, Walker MJ, Scott JR, Weiler-Mithoff EM. The timing of autologous latissimus dorsi breast reconstruction and effect of radiotherapy on outcome. J Plast Reconstr Aesthet Surg 2009; 62:488-93. 21. Tran NV, Evans GR, Kroll SS, Baldwin BJ, Miller MJ, Reece GP, et al. Postoperative adjuvant irradiation: effects on transverse rectus abdominis muscle flap breast reconstruction. Plast Reconstr Surg 2000; 106: 313-7. 22. Gill PS, Hunt JP, Guerra AB, Dellacroce FJ, Sullivan SK, Ðoraski J, et al. A 10-year retrospective review of 758 DIEP flaps for breast reconstruction. Plast Reconst Surg 2004; 113:1153-60. 23. Chatterjee JS, Lee A, Anderson W, Baker L, Stevenson JH, Dewar JA, et al. Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. Br J Surg 2009; 96:1135-40. 24. Carlson GW, Page AL, Peters K, Ashinoff R, Schaefer T, Losken A. Effects of radiation therapy on pedicled transverse rectus abdominis myocutaneous flap breast reconstruction. Ann Plast Surg 2008; 60: 568-72. 25. Halyard MY, McCombs KE, Wong WW, Buchel EW, Pockaj BA, Vora SA, et al. Acute and chronic results of adjuvant radiotherapy after mastectomy and Transverse Rectus Abdominis Myocutaneous (TRAM) flap reconstruction for breast cancer. Am J Clin Oncol 2004; 27: 389-94. 26. Neyt MJ, Blondeel PN, Morrison CM, Albrecht JA. Comparing the cost of delayed and immediate autologous breast reconstruction in Belgium. Br J Plast Surg 2005; 58: 493-7. ENGLISH SUMMARY Results of Immediate Breast Reconstructions at Landspítali - The National University Hospital of lceland, in 2008-2010 Jonsdottir K, Rafnsdottir SL, Kjartansdottir Th, Kristvinsson H, Jonsson Th, Asgeirsson KS Introduction: In late 2007, the availability of immediate breast reconstructions increased as a result of the establishment of an oncoplastic breast surgical service at Landspítali - The National University Hospital The aim of this study was to look at the rates and early complications of immediate breast reconstructions in our hospital in 2008-2010 and compare with the results from the UK National Mastectomy and Breast Reconstruction Audit (NMBRA). Material and methods: This is a retrospective population-based study, including all women who had immediate breast reconstruction at Landspítali in 2008-2010. Results: 319 mastectomies and 157 breast reconstructions were performed. Of these, 98 (62%) were immediate, (mean age 49, 29-69). The immediate breast reconstruction rate was therefore 31%, with a respective 55% for patients 50 years old or younger. In comparison, the rate was 5% in 2000-2005. Immediate reconstructions with an extended autologous latissimus dorsi flap were performed in 25 (26%) cases and implant based reconstructions in the remaining (n=73, 74%). Inpatient complications occurred in 12 (12%) patients and 5 needed reoperation (3 post-operative bleeding, 1 skin necrosis, 1 imminent LD-flap failure). Readmission due to complications after discharge occurred in 14 (14%), while 37 (38%) developed mild complications not requiring readmission. The results were comparable to NMBRA, although the rates of autologous flap reconstructions were significantly higher than in this study (63% vs. 26%). Conclusion: As a result of the establishment of an oncoplastic breast surgical service at Landspítali, the rates of immediate breast reconstruction have increased significantly (from 5% to 31%). The complication rates are low and similarto NMBRA. Key words; Breast surgery, breast cancer, immediate breast reconstruction, oncoplastic breast surgery, national mastectomy and breast reconstruction audit (NMBRA). Correspondence: Kristján Skúli Ásgeirsson, kriskuli@landspitali.is Department of Surgery, Landspitali - The National University Hospital of lceland. LÆKNAblaðið 2012/98 463

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