Læknablaðið : fylgirit - 03.01.2017, Qupperneq 16

X V I I I V Í S I N D A R Á Ð S T E F N A H Í
F Y L G I R I T 9 1
16 LÆKNAblaðið/Fylgirit 91 2017/103
eMpowerment, Usefulness, Success, Interest and Caring. The MUSIC
Model of Academic Motivation Inventory (MMAMI) was originally
developed in English to assist teachers and researchers in assessing their
students´motivation and in developing a classroom context that increases
engagement (Jones, 2012). The various, albeit similar versions, have been
validated through exploratory and confirmatory factor analyses in several
contexts from elementary to university level (EFA/CFA; Jones & Wilkins,
2013, 2015; Jones & Skaggs, 2016; Jones & Sigmon, 2016).
Methods: For the Icelandic version, back-translation was used followed
by expert meetings to gain semantic equivalence. To obtain translation in-
variance, EFA was employed, using principal axis factoring with promax
rotation, and subsequently CFA with a different sample, to test for model
fit.
Results: Results replicated the findings obtained with the original version
and confirmed the five-factor structure, providing validity evidence for
the scores produced by the Icelandic version.
Conclusion: The practicality of the inventory will be highlighted using an
example of recent research from the School of Health Sciences, University
of Iceland. The inventories and directions can be obtained on the MUSIC
website, www.themusicmodel.com
E 28 Effect of rehabilitation on health status, stress, anxiety and
depression in women with fibromyalgia
Marta Gudjónsdóttir1, Gunnhildur L. Marteinsdóttir2, Nína K. Guðmundsdóttir2,
Hlín Bjarnadóttir2, Björg Þorleifsdóttir3, Ingólfur Kristjánsson2
1Department of Physiology, Faculty of Medicine, University of Iceland, 2Department of
rheumatic diseases, Reykjalundur Rehabilitation Centre, 3Faculty of Medicine, University of
Iceland
martagud@hi.is
Background: Fibromyalgia (FM) is a debilitating condition character-
ised by widespread chronic pain, fatique, psychosocial stress and dep-
leted exercise tolerance.
Objective of this study was to explore the effect of a 6 week rehabilita-
tion programme (6WR) on health status and psychological wellbeing
among FM female patients and compare it to a group of healthy female
controls.
Methods: 33 women with FM entered the study but 8 were excluded
due to sleep apnoea or periodic leg movements. 25 patients and 12
controls (age- and BMI-matched: 46.8±8.7 vs 50.0±8.4 years and 31.6±5.3
vs 29.1±4.2 kg/m2 respectively) completed the Fibromyalgia Impact
Questionnaire (FIQ) and the Depression Anxiety and Stress Scale
Questionnaire (DASS). Their functional exercise capacity was measured
by the Six Minute Walk Test (6MWT).
Results: Before rehabilitation the patients scored higher than controls in
FIQ (59.1±12.3 vs 5.1±5.8), DASS depression (10.3±6.9 vs 1.0±1.2), DASS
anxiety (8.0±6.3 vs 1.4±2.6) and DASS stress (12.2±5.9 vs 2.6±3.2) and
they walked shorter distance in 6MWT (564±58 vs 659±45 m; 86±10 vs
103±6 % predicted). Patients improved in FIQ, DASS depression and
6MWT during 6WR and were close to it in DASS anxiety and stress
(p=0.065) whereas controls remain unchanged.
Conclusion: Health status, functional exercise capacity and
psychological wellbeing is impaired among FM patients compared to
controls. However, it improves significantly during the rehabilitation
in our study.
E 29 Ambulatory and hospital care for children in times of austerity
after the 2008 economic collapse
Geir Gunnlaugsson
Faculty of Social and Human Sciences, University of Iceland
geirgunnlaugsson@hi.is
Introduction: The economic collapse in Iceland in October 2008 resulted
in deep cuts in costs of healthcare services. Here the aim is to review and
describe ambulatory and hospital care of children given by general pract-
itioners (GPs) and paediatricans, and evaluate the impact of the economic
collapse.
Materials and methods: Data was retrieved from national databases on
ambulatory and hospital care. Nine ICD-10 diagnoses for children 0-14
years old, known to have socioeconomic gradient, were selected for
scrutiny in addition to survival rates of children with acute leukemia.
Results: In the period 2005-2013, no markant change is seen on the
number of consultations by GPs per child and year (median 1.63, range
1.43-1.82). The median number of consultations of pediatricians who
charge user-fees increased from an average of 0.53 visits per child before
the collapse to 0.63 following the crisis. In 2005-2013, the incidence of
nine selected ICD-10 diagnosis did not change that could be related to
the economic collapse. Survival rates for childhood acute leukemia shows
sign of improvement in the period 1989-2013.
Conclusions: Austerity measures following the economic collapse in 2008
in Iceland did not negatively impact on diverse indicators for ambulatory
and hospital care of children. High quality healthcare services continued
to be delivered to children amidst crisis of historic proportion, through
for example continued policy of universal access that was mostly free of
charge.
E 30 Placental protein 13 (PP13)-induced vasodilation in pregnant
and non-pregnant rat arteries
Tijana Drobnjak1, Sveinbjörn Gizurarson2, Natalia Gokina3, Berthold Hupertz4,
Maurizio Mandala5, George Osol6
1Faculty of Pharmaceutical Sciences, UI, 2University of Iceland, 3Universitiy of Vermont,
4Medical University of Graz, 5University of Calabria, 6University of Vermont
tid4@hi.is
Introduction: PP13 was recently shown to be a potent vasodilator of small
arteries, although the underlying mechanism of action is still not known.
In this study its target in resistance vessels from two regional circulations
(uterine and splanchnic) was investigated and the contribution of nitric
oxide and prostaglandin signaling pathways to its vasodilatory actions
was evaluated.
Materials and methods: Uterine arcuate (UA) and mesenteric arteries
(MA, 200-300 mm diameters) were disected from non-pregnant and
mid-pregnant (day 15/22; n=27) Sprague Dawley rats. All vessel were
cannulated and pressurized to 50 mmHg within an arteriograph and
then preconstricted with phenylephrine or synthetic thromboxane ana-
log U46619. Increasing PP13 concentrations (10-13 - 10-8 M) were applied,
and lumen diameter changes recorded in the presence of pharmacologic
inhibitors.
Results: PP13 was showed to be a potent vasodilator, having similar
efficacy and sensitivity in mesenteric and uterine resistance arteries: half-
-maximal responses (EC50) were observed at concentrations <1 pM, and
efficacies ranging from 38-50%. PP13-induced vasodilation of both uterine
and mesenteric arteries is initiated by endothelial rather than vascular
smooth muscle cells. The relaxation does not involve prostacyclin recept-