Læknablaðið - 01.11.2023, Blaðsíða 28

512 L ÆKNABL AÐIÐ 2023/109
R A N N S Ó K N
E N G L I S H S U M M A R Y
A 50 year old man with progressive weakness in lower limbs
Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare neurological disorder
caused by autoimmune antibodies attacking the presynaptic neuromuscular
junction, in some cases caused by underlying cancer. The main clinical
finding is fluctuating weakness of the extremities and a triad of symtoms
can help physicians suspect the disease. A key to the diagnosis are the
electrophysiological abnormalities seen in this group of diseases. Treatment
with symtomatic and/or immunosuppressive therapy is important as well as
a workup for possible malignancy. This article identifies the clinical features,
diagnosis and treatment of this uncommon disease.
doi 10.17992/lbl.2023.11.768
Brynhildur Thors1
Bjarni Guðmundsson2
1Neurological department Karolinska University Hospital, Stockholm
2Neurology department Landspitali-University Hospital.
Correspondence: Brynhildur Thors, bthors@gmail.com
Key words: Lambert-Eaton Myasthenic Syndrome, proximal weakness,
neuromuscular junction disorder, repetitive nerve stimulation, paraneoplastic
phenomenon.
Heimildir
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Síðumúli 16 I 108 Reykjavík I Sími 580 3900 I fastus.is
Vscan Air CL og SL eru lítil og nett ómskoðunartæki sem
hvort um sig hafa tvo mismunandi ómhausa sem skila
kristaltærum myndum beint í spjaldtölvu eða síma.
Nánari upplýsingar og ráðgjöf veita:
Guðmundur Hreiðarsson: gh@fastus.is – S: 891 6109
Erna Dís Brynjúlfsdóttir: erna@fastus.is – S:843 3919
Vscan Air SL
Tveir ómhausar:
„Sector-phased“ ómhaus,
til að meta ástand hjarta,
og linear ómhaus.
Vscan Air CL
Tveir ómhausar:
Abdominal
og linear ómhaus .
HealthCo
Nýtt
Vscan Air