Læknablaðið - 15.03.1993, Blaðsíða 6

94
LÆKNABLAÐIÐ 1993; 79: 94-5
Þorsteinn Loftsson
SKRÁ YFIR VÍSINDAGREINAR
1. T. Loftsson. »Evaluation of Methylthiomethyl,
Methylsulfinylmethyl and Methylsulfonylmelhyl 2-
Acetoxybenzoates as Prodrug Forms of Aspirin and
Study of the Chemistry of these Compounds and Related
Compounds both in vitro and in vivo«. University of
Kansas, 1979 (Ph.D. Thesis).
2. T. Loftsson, J. Kaminski og N. Bodor. »Improved
delivery through biological membranes VIII. Design,
synthesis and in vivo testing of true prodrugs of aspirin«.
J Pharm Sci; 70: 743-9 (1981).
3. T. Loftsson og N. Bodor. »Improved delivery through
biological membranes IX. The kinetics and mechanis of
hydrolysis of methylsulfinylmethyl 2-acetoxybenzoate and
related aspirin prodrugs«. J Pharm Sci; 70: 750-5 (1981).
4. T. Loftsson og N. Bodor. »lmproved delivery through
biological membranes X. Percutaneous absorption
and metabolism of the methylsulfinylmethyl 2-
acetoxybenzoate and related aspirin prodrugs«. J Pharm
Sci; 70: 756-8 (1981).
5. Þorsteinn Loftsson. »Þróun lyfja gegn illkynja
sjúkdómum«. Tímarit um lyfjafræði; 16: 20-2 (1981).
6. T. Loftsson. »Experimental and theoretical model for
studying simultaneous transport and metabolism of drugs
in exicised skin«. Arch Pharm Chemi Sci Ed; 10:17-24
(1982).
7. T. Loftsson og N. Bodor. »Synthesis and hydrolysis
of some pivaloyloxymethyl and pivaloyl derivatives of
phenolic compounds«. Arch Pharm Chemi Sci Ed; 10:
104-10 (1982).
8. Þorsteinn Loftsson. »Hönnun á nýjum lyfjum«. Tímarit
um lyfjafræði; 17( 1): 27-32 (1982).
9. Þorsteinn Loftsson. »Upplýsingagjöf«. Tímarit um
lyfjafræði; 18(1); 13-14 (1983).
10. N. Bodor, Y. Oshiro, T. Loftsson, M. Katovich og
W. Caldwell. »Soft drugs VI. The application of the
inactive metabolite approach for design of soft /3-
blockers«. Pharm Res; 1: 120-5 (1984).
11. T. Loftsson, M. Matsuo, R.W. Caldwell,
N. Gildersleeve og N. Bodor. »Synthesis and evaluation
of novel lidocaine sulfur analogs«. Int J Pharm; 22: 345-
55 (1984).
12. Þorsteinn Loftsson. »Frásog lyfja í húð«. Tímarit um
lyfjafræði; 20(1); 24-8 (1985).
13. T. Loftsson. »The effect of ionization on partition
coefficients and topical delivery«. Acta Pharm Suec; 22:
209-14 (1985).
14. N. Bodor og T. Loftsson. »Novel chemical approaches
for sustained drug delivery í Controlled drug delivery.
Fundamentals and applications.« (J.R. Robinson og V. H.
L. Lee, Eds.) New York: Marcel Dekker Inc., 1987: 337-
71.
15. T. Loftsson, N. Gildersleeve og N. Bodor. »The
effect of vehicle additives on the transdermal delivery
of nitroglycerin«. Pharm Res; 4: 436-7 (1987).
16. K.H. Rand, I. Raad, A. E1 Koussi, H.J. Houck,
W. Brey, J. Rocca, T. Loftsson, og N. Bodor.
»Trifluorothymidine: Potential non-invasive diagnosis
of herpes simplex infection using 19F nuclear magnetic
resonance in a murine hepatitis model«. J Virol Methods;
18: 257-70 (1987).
17. Þorsteinn Loftsson. »Lyf við gelgjubólum«. Mixtúra,
blað lyjafræðinema; 1: 28-9 (1987).
18. M.E. Brewster, K. S. Estes, T. Loftsson,
R. Perchalski, H. Derendorf, G. Mullersman og N. Bodor.
»Improved delivery through biological membranes XXXI:
Solubilization and stabilization of an estradiol chemical
delivery system by modified /3-cyclodextrins«. J Pharm
Sci; 77: 981-5 (1988).
19. M.E. Brewster, T. Loftsson, K.S. Estes,
G. Mullersman, H. Derendorf og N. Bodor. »Water
soluble complexes of a brain-targeted drug delivery
system«. I , Proceedings of the Fourth Intemational
Symposium on Cyclodextrins (O. Huber og J. Szejtli,
Eds.). Vestur-Þýskaland: Kluwer Academic Publishers,
1988: 399-405.
20. T. Loftsson, N. Gildersleeve, R. Soliman og
N. Bodor. »Effect of oleic acid on diffusion of dmgs
through hairless mouse skin«. Acta Pharm Nordica; 1:
17-22 (1989).
21. Þorsteinn Loftsson. »Rannsóknir í lyfjafræði lyfsala«.
Tímarit um lyfjafræði; 24(1); 21-6 (1989).
22. T. Loftsson og N. Bodor. »Effects of
2-hydroxypropyl-/3-cyclodextrin on the aqueous solubility
of dmgs and transderma delivery of 17/3-estradiol«. Acta
Pharm Nordica; 1: 185-94 (1989).
23. T. Loftsson, G. Somogyi og N. Bodor. »Effect
of choline esters and oleic acid on the penetration of
acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic
acid and trifluorothymidine across hairless mouse skin in
vitro«. Acta Pharm Nordica; 1: 279-86 (1989).
24. T. Loftsson, S. Bjömsdóttir, G. Pálsdóttir og
N. Bodor. »The effects of 2-hydroxypropyl-/3-cyclodextrin
on the solubility and stability of chlorambucil and