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Læknablaðið - 01.12.2016, Blaðsíða 22

Læknablaðið - 01.12.2016, Blaðsíða 22
550 LÆKNAblaðið 2016/102 R A N N S Ó K N ENGLISH SUMMARY Introduction: Thoracic aortic aneurysm (TAA) is an uncommon disease where treatment is complex and associated with significant comorbidity. The main aim of this study was to evaluate the outcomes of operations for TAA in Iceland with emphasis on postoperative complications, 30 day mortality and survival. Materials and methods: A retrospective study on 105 patients (mean age 60.7 yrs., 69.5% males) that underwent operations for TAA between 2000 and 2014 in Iceland. Patients with aortic injury or acute aortic dissection were excluded. Clinical information was collected from hospi- tal charts and long-term survival estimated by Kaplan-Meier method. Mean follow-up was 5.7 yrs. Results: Bicuspid aortic valve was present in 52 patients (51.0%) and family history was positive in 10 of the cases (9.5%). Every other pati- ent (50.5%) was asymptomatic and diagnosed incidentally. The most common procedure was aortic root replacement using biological prost- hesis. Two out of three patients had complications, that were regarded as major in 31.4% of cases, however, stroke was only detected in 2 (1.9%) patients. Two patients died within 30 days postoperatively (1.9%). The overall survival at one year was 95.1%; more favorable for males compared to females (97.2 vs. 90.4%, p=0.0012, log rank test) and at 5 years 90.3%. Conclusions: Outcome following surgery for TAA in Iceland is comparable to studies in neighbouring countries. The complications rate is high, however, the stroke rate was low, as was 30 day mortality. Longterm survival is favorable, and is more favorable for males than females. Results of operations for ascending aortic aneurysm in Iceland 2000-2014 Helga Björk Brynjarsdóttir1, Inga Hlíf Melvinsdóttir2, Tómas Guðbjartsson1,3, Arnar Geirsson3 1Faculty of Medicine, University of Iceland, 2Landspitali University Hospital, 3Department of Cardiothoracic Surgery, Landspitali University Hospital. Key words: Thoracic aortic aneurysm, ascending aorta, open heart surgery, complications, operative mortality, survival. Correspondance: Arnar Geirsson, arnarge@landspitali.is STYRKUMSÓKNIR Rannsóknarsjóður Hjartasjúkdómafélags íslenskra lækna auglýsir eftir styrkumsóknum vegna rannsóknarverkefna sem tengjast hjarta- og æðasjúkdómum. Hægt er að sækja um styrki frá 250.000 og að hámarki 1.000.000 króna. Í umsókn þarf eftirfarandi að koma fram: 1. Titill rannsóknarverkefnis. 2. Nafn umsækjanda og leiðbeinanda ef við á, ásamt því hvar rannsóknarvinnan er unnin. 3. Stutt samantekt um rannsóknarverkefnið. 4. Hversu háan styrk er sótt um og kostnaðaráætlun um hvernig ráðgert er að nota styrkinn. Styrkumsóknir þarf að senda bréflega til Ragnars Danielsen, Hjartaómunareiningu 13F, Hjartadeild, Landspítala Hringbraut, eða með tölvu- pósti á ragnarda@landspitali.is, fyrir 2. janúar 2017.

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