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Læknablaðið - 15.09.1988, Qupperneq 20

Læknablaðið - 15.09.1988, Qupperneq 20
268 LÆKNABLAÐIÐ infarction were given 20 ml cod liver oil a day for six weeks, either immediately after the control period, weeks 0-6 (n= 10), or during weeks 6-12 (n = 8). 48 hour Holter monitoring was carried out before cod liver oil administration and at the end of weeks 6 and 12. The eicosapantaenoic acid content of plasma phospholipids was increased by 230% during cod liver oil administration. However, no significant change was observed in the 24 hour prevalence of ventricular extrasystoles or other arrhythmias during the study period. The mean ln number of ventricular extrasystoles was 2,95 ±0.51 (SD) during cod liver oil ingestion and 2,63 ±0.30 off cod liver oil. HEIMILDIR 1. Dyerberg J, Bang HO, Stoffersen E, Moncada S, Vane JR. Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis? Lancet 1978; ii: 117-19. 2. Kromhout D, Bosschieter EB, Coulander CdeL. The inverse relation between fish consumption and 20-year mortality from coronary heart diseases. N Engl J Med 1985; 313: 1205-9. 3. Shekelle RB, Missel LaVon RD, Oglesby P, Shryock AM, Stamler J. Letter to the Editor. N Engl J Med 1985; 313: 820-1. 4. Vollset SE, Heuch I, Bjelke E. Letter to the Editor. N Engl J Med 1985; 313: 820-1. 5. Curb JD, Reed DM. Letter to the Editor. N Engl J Med 1985; 313: 821. 6. Weiner BH, Ockene IS, Levine HF, Cuenoud HF, Fisher M, Johnson BF, Daoud AS, Jarmolych J, Hosmer D, Johnson MH, Natale A, Vaudreuil C, Hoogasian JJ. Inhibition of atherosclerosis by cod liver oil in a hyperlipidemic swine model. N Engl J Med 1986; 315: 841-6. 7. Landymore RW, Kinley CE, Cooper JH, MacAuley M, Sheridan B, Cameron C. Cod-liver oil in the prevention of intimal hyperplasia in autogenous vein grafts used for arterial bypass. J Thorac Cardiovasc Surg 1985; 351-7. 8. Phillipson BE, Rothrock DW, Conner WE, Harris WS, Illingworth RD. Reduction of plasma lipids, lipoproteins and apoproteins by dietary fish oils in patients with hypertriglyceridemia. N Engl J Med 1985; 312: 1210-16. 9. Saynor R, Verel D, Gillott T. The long-term effect of dietary supplementation with fish lipid concentrate on serum lipids, bleeding time, platelats and angina. Atherosclerosis 1984; 50: 3-10. 10. Schoene NW, Fiore D. Effect of a diet containing fish oil on blood pressure in spontaneously hypertensive rats. Prog Lipids 1981; 11: 569-70. 11. Woodcock BE, Smith E, Lambert WH, Morris Jones W, Galloway JH, Greaves M, preston FE. Beneficial effect of fish oil on blood viscosity in peripheral vascular disease. Br Med J 1984; 288: 592-4. 12. Benediktsdóttir VE, Guðbjarnason S. Dietary cod-liver oil modifies sarcolemmal lipid compostition and reduces the incidence of ventricular fibrillation in rats. 13th Scandinavian Symposium on Lipids 1985. Proceedings. 13. Cupl BR, Lands WEM, Lucchesi BR, Pitt R, Romson J. The effect of dietary supplementation of fish oil on experimental myocardial infarction. Prostaglandins 1980; 20: 1021-31. 14. Terashita Z, Fukui H, Hirata M, Terao S, Ohkawa S, Nishiwak K, Kikuchi S. Coronary vascoconstriction and PGI2 release by leucotrienes in isolated guinea pig hearts. Eur J Pharmacol 1981; 73: 357-61. 15. Lee TH, Hoover RL, Williams JD, Sperling RI, Ravalese J, Spur BW, Robinson DR, Corey EJ, Lewis RA, Austen KF. Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leucotriene generation and neutrophil function. N Engl J Med 1985: 312: 1217-24. 16. Murnaghan MF. Effect of fatty acids on the ventricular arrhythmia threshold in the isolated heart of the rabbit. Br J Pharmacol 1981; 73: 909-15. 17. Litvitsky PF, Bobylev RV, Kurdina MI, Ivanow VP. Effect of different combinations of exogenous higher fatty acids on cardiac function during coronary ischæmia and reperfusion. Bull Eksp Biol Med 1984; 97: 145-9. 18. Das UN. Possible role of prostaglandins in the pathogenesis of cardiomyopathies. Med Hypotheses 1981; 7: 651-7. 19. Mullane KM, Read N, Salmon JA, Moncada S. Role of leucocytes in acute myocardial infarction in anesthetized dogs: Relationship to myocardial salvage by anti-inflammatory drugs. J Pharmacol Exp Ther 1984; 223: 510-22. 20. Kennedy HL, Whitlock JA, Sprague MK, Kennedy LJ, Buckingham TA, Goldberg RJ. Long-term follow-up of asymptomatic healthy subjects with frequent and complex ventricular ectopy. N Engl J Med 1985; 312: 193-7. 21. Abdalla ISH, Prineas RJ, Neaton JD, Jacobs DR, Crow RS. Relation between ventricular premature complexes and sudden cardian death in apparently healthy men. Am J Cardiol 1987; 60: 1036-42. 22. Ruberman W, Winblatt E, Goldberg JD, Franck CW, Shapiro S. Ventricular premature beats and mortality after myocardial infarction. N Engl J Med 1977; 297: 750-7. 23. Moss AJ, Davis HT, DeCamilla, Bayer LW. Ventricular ectopic beats and their relation to suddden and nonsudden cardiac death after myocardial infarction. Circulation 1979; 60: 998-1003. 24. Ruberman W, Weinblatt E, Goldberg JD, Franck CW, Chaudhary BS, Shapiro S. Ventricular premature complexes and sudden death after myocardial infarction. Circulation 1981; 64: 297-305.
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