Læknablaðið

Volume

Læknablaðið - 01.10.1966, Page 52

Læknablaðið - 01.10.1966, Page 52
218 LÆKNABLAÐIÐ of confusion. On admission, clinical examination revealed crepitations over both lungfields and enlarged liver. He was found uraemic, hyper- kaliaemic, hyponatriaemic, hypochloroaemic and with lowered bicar- bonate in plasma. Roentgen examination showed infiltrations in both lungs. Electrocardiogrammes are shown and explained in figs. 3 and 4. During the first day the pt. was anuric. He was then cautiously infused and afterwards quit some urine. However, during the 3rd day the pt. suffered increasingly from dyspnoe and died. The post mortem ex- amination showed massive lung oedema, fluid in pericardium, pleura and peritoneum, necrosis and haemorrhages in liver and parenchym- atous degeneration of kidneys (cf. fig. 5). Table 3 shows the amounts of tetrachloromethan, trichloroethylene and tetrachloroethylene sold during the years 1952—1964. The figures indicate that trichloroethylene was sold in amounts approximateiy five times greater than those of tetrachloromethan, whereas tetrachloro- ethylene was sold in negligible amounts. From this and the obser- vations mentioned above, it was concluded that the incidence of acute, serious poisonings with tetrachloromethan had been absolutely greater during the years 1945—1964 than that of serious poisonings d.ue to trichloroethylene. It was likewise concluded that tetrachloromethan must be definitely more dangerous than trichloroethylene. Emphasis was therefore given to the rigorous restriction on the sale of tetrachloro- methan stipulated in a newly drafted bill on toxic and dangerous sub- stances. It was also suggested that methylchloroform, being less dang- erous than tetrachloromethan and trichloroethylene, should be substi- tuted, as far as is possible, for these substances for domestical and industrial usage. (Our gratitude is due to professor Sigurður Samúelsson and as- sociate professor Theodór Skúlason, Department of Intsrnal Medicine, Landspítalinn (The University Hospital), Reykjavík, and to physician in chief Óskar Þórðarson, Department of Internal Medicine, Borgar- spítalinn (The Municipal Hospital), Reykjavík, for giving us access to the case reports of the patients treated in their departments and per- mission to use the information contained therein for this publication.) Heimildir. Abrahamsen, A. M.: Quantitative estimation of trichloroacetic acid in urine and serum in trichloroethylene poisoning. Acta pharmacol. et toxicol. 1960, 17, 288—294. Alha, A.: Carbon tetrachloride mass poisoning. Ann. MecL. Intern. Fenn. 1950, 39 (suppl. 8), 3—32. Bartonícek, V.: MetaboJism and excretion of trichloroethylene after inhalation by human subjects. Brit. J. lndustr. Med. 1962, 19, 134—141. Dvorácková, I.: Ein fall von tödlicher oraler Tetrachlorokohlenstoff- vergiftung. Arch. f. Toxikologie 1963, 20, 72—78. Fassett, D. W.: Toxicology of organic compounds: A review of current problems, Ann. Rev. Pharmacol. 1963, 3, 267—292.
Page 1
Page 2
Page 3
Page 4
Page 5
Page 6
Page 7
Page 8
Page 9
Page 10
Page 11
Page 12
Page 13
Page 14
Page 15
Page 16
Page 17
Page 18
Page 19
Page 20
Page 21
Page 22
Page 23
Page 24
Page 25
Page 26
Page 27
Page 28
Page 29
Page 30
Page 31
Page 32
Page 33
Page 34
Page 35
Page 36
Page 37
Page 38
Page 39
Page 40
Page 41
Page 42
Page 43
Page 44
Page 45
Page 46
Page 47
Page 48
Page 49
Page 50
Page 51
Page 52
Page 53
Page 54
Page 55
Page 56
Page 57
Page 58
Page 59
Page 60
Page 61
Page 62
Page 63
Page 64
Page 65
Page 66
Page 67
Page 68
Page 69
Page 70
Page 71
Page 72
Page 73
Page 74
Page 75
Page 76
Page 77
Page 78
Page 79
Page 80
Page 81
Page 82
Page 83
Page 84
Page 85
Page 86
Page 87
Page 88
Page 89
Page 90
Page 91
Page 92
Page 93
Page 94
Page 95
Page 96
Page 97
Page 98
Page 99
Page 100
Page 101
Page 102
Page 103
Page 104
Page 105
Page 106
Page 107
Page 108

x

Læknablaðið

Direct Links

If you want to link to this newspaper/magazine, please use these links:

Link to this newspaper/magazine: Læknablaðið
https://timarit.is/publication/986

Link to this issue:

Link to this page:

Link to this article:

Please do not link directly to images or PDFs on Timarit.is as such URLs may change without warning. Please use the URLs provided above for linking to the website.