Læknablaðið - 15.03.1996, Blaðsíða 12

202
LÆKN ABLAÐIÐ 1996; 82
Góðar lífshorfur karla með
sáðkrabbamein
Afturskyggn rannsókn á íslenskum körlum greindum
1971-1990
Tómas Guðbjartsson1', Reynir Bjömsson2’, Kjartan Magnússon3’, Sigurður Bjömsson3’, Guðmundur
Vikar Einarsson1'2>
Guðbjartsson T, Björnsson R, Magnússon K,
Björnsson S, Einarsson GV
Good survival of Icelandic men diagnosed with testi-
cular seminoma bctween 1971 and 1990 - A retro-
spective study
Læknablaðið 1996; 82: 202-10
Testicular cancer is the most common cancer diag-
nosed in males aged 20 to 34 in Iceland. A retro-
spective population-based study was carried out on
all Icelandic males diagnosed between 1971 and 1990
to evaluate presentation and survival of seminoma
in Iceland.
Fortyseven males with average age of 36 years
(range 21-71) were included. Clinical informations
were gained from the Icelandic Cancer Registry and
hospital records. The staging system used was a
modification of the system orginally proposed by
Boden and Gibb and crude probability of survival
was evaluated with the Kaplan-Meier method.
Age standardized incidence for seminoma was 2.0/
100,000 males per year for the whole period. Forty-
five patients were diagnosed with symptoms where
testicular swelling (98%) and pain (42%) were the
most common symptoms. Two patients were diag-
nosed incidentally. All the patients except one un-
derwent orchiectomy, 66% also received radiother-
apy and 9% chemotherapy. Average tumor diame-
ter was 8 cm before 1981 but 5.2 cm after 1981
Frá '’handlækninga- og þvagfæraskurðdeild Landspítala,
2|læknadeild Háskóla íslands, 3|krabbameinslækningadeild
Landspítala. Fyrirspurnir, bréfaskipti; Tómas Guðbjartsson
Svanebácksvágen 25B, S-260 40 Viken, Sverige. Netfang:
TGISKIRtffigemini. Idc.lu.se
(p=0.02). Most patients were diagnosed in stage I
(73%), but 27% had disseminated disease at diag-
nosis (stage II-IV), most commonly retroperitoneal
lymphnode metastases (85%). Crude five and 10
year survival was 89% and 84% respectively. Nine
patients have died (August 1994) but none of semi-
noma.
The incidence of seminoma is moderate in Iceland
compared to the Nordic countries. Clinical symp-
toms and stage at diagnosis are similar. Survival is
excellent for the group as a whoie. For small Iocal-
ized tumors orchiectomy and surveillance seem to
be an appropriate approach.
Ágrip
Krabbamein í eistum eru algengustu illkynja
æxlin sem greinast í ungum karlmönnum á Is-
landi. Með öflugri geislameðferð og nýjum
krabbameinslyfjum hafa lífsgæði og lífshorfur
þessara sjúklinga batnað og í dag eru þau í hópi
krabbameina sem mestar líkur eru á að lækna.
Markmið rannsóknarinnar var að kanna með
hvaða hætti sáðkrabbamein (seminoma) grein-
ist á íslandi, nýgengi, stigun og lífshorfur sjúk-
linganna við greiningu.
Rannsóknin er afturskyggn og nær til allra
íslenskra karla sem greindust með sáðkrabba-
mein á íslandi frá 1971 til 1990. Alls greindust
47 einstaklingar og var meðalaldur 36 ár, ald-
ursbil 21-71 ár. Úr sjúkraskrám fengust upplýs-
ingar um aldur sjúklinganna, greiningarár,
einkenni, rannsóknir og meðferð. Öll æxlin
voru stiguð samkvæmt afbrigði af Boden og
Gibb stigunarkerfi og lífshorfur reiknaðar með
Kaplan-Meier aðferð. Loks var kannað hverjir
hefðu látist vegna sáðkrabbameins.