Læknablaðið

Årgang

Læknablaðið - 15.03.2010, Side 17

Læknablaðið - 15.03.2010, Side 17
FRÆÐIGREINAR RANNSÓKNIR 7. Van de Werf F, Ardissino D, Betriu A, et al. Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2003; 24: 28-66. 8. McNamara RL, Wang Y, Herrin J, et al. Effect of door-to- balloon time on mortality in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol 2006; 47: 2180-6. 9. Steg PG, Bonnefoy E, Chabaud S, et al. Impact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty: data from the CAPTIM randomized clinical trial. Circulation 2003; 108: 2851-6. 10. Welsh RC, Chang W, Goldstein P, et al. Tlme to treatment and the impact of a physician on prehospital management of acute ST elevation myocardial infarction: insights from the ASSENT-3 PLUS trial. Heart 2005; 91:1400-6. 11. Pinto DS, Kirtane AJ, Nallamothu BK, et al. Hospital delays in reperfusion for ST-elevation myocardial infarction: implications when selecting a reperfusion strategy. Circulation 2006; 114: 2019-25. 12. Nallamothu BK, Antman EM, Bates ER. Primary percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: does the choice of fibrinolytic agent impact on the importance of time-to- treatment? Am J Cardiol 2004; 94: 772-4. 13. Þorgeirsson G, Sverrisson JT, Danielsen R, Gunnarsson GT, Eyjólfsson K. Nefndarálit um fýsileika þess að taka upp hjartaþræðingar á FSA; 2006 12.október. 14. Gíslason GH, Baldursson G, Harðarson T. Segaleysandi meðferð í Egilsstaðalæknishéraði. Fimm sjúkratilfell á tveggja ára tímabili. Læknablaðið 1996; 82: 516-20. 15. Libungan BG, Eyjólfsson K, Þorgeirsson G. Bráðar kransæðaþræðingar á íslandi - Árangur á fyrsta ári sólarhringsgæsluvaktar. Læknablaðið 2008; 94:103-7. 16. Thygesen K, Alpert JS, White HD. Universal definition of myocardial infarction. J Am Coll Cardiol 2007; 50: 2173-95. 17. Amar DO, Danielsen R. Klínískar leiðbeiningar um greiningu og meðferð sjúklinga með brjóstverk. http:// Iandspitaliis/lisalib/getfileaspx?itemid=19461 Janúar 2009. 18. Morrison LJ, Verbeek PR, McDonald AC, Sawadsky BV, Cook DJ. Mortality and prehospital thrombolysis for acute myocardial infarction: A meta-analysis. JAMA 2000; 283: 2686-92. 19. Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med 2003; 349: 733-42. 20. Van de Werf F, Bax J, Betriu A, et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2008; 29: 2909- 45. 21. Kalla K, Christ G, Karnik R, et al. Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation 2006; 113: 2398-405. 22. Stenestrand U, Lindback J, Wallentin L. Long-term outcome of primary percutaneous coronary intervention vs prehospital and in-hospital thrombolysis for patients with ST-elevation myocardial infarction. JAMA2006; 296:1749-56. 23. Nallamothu BK, Bradley EH, Krumholz HM. Time to treatment in primary percutaneous coronary intervention. N Engl J Med 2007; 357:1631-8. 24. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second Intemational Study of Infarct Survival) Collaborative Group. Lancet 1988; 2: 349-60. 25. Sabatine MS, Cannon CP, Gibson CM, et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352:1179-89. 26. Johanson P, Jemberg T, Gunnarsson G, Lindahl B, Wallentin L, Dellborg M. Prognostic value of ST-segment resolution- when and what to measure. Eur Heart J 2003; 24: 337-45. 27. Khoobiar S, Mejevoi N, Kaid K, et al. Primary percutaneous coronary intervention for ST-elevation myocardial infarction using an intravenous and subcutaneous enoxaparin low molecular weight heparin regimen. J Thromb Thrombolysis 2008; 26:85-90. 28. Wijeysundera HC, You JJ, Nallamothu BK, Krumholz HM, Cantor WJ, Ko DT. An early invasive strategy versus ischemia-guided management after fibrinolytic therapy for ST-segment elevation myocardial infarction: a meta-analysis of contemporary randomized controlled trials. Am Heart J 2008; 156: 564-72, 72 el-2. Management of patients with STEMI transported with air-ambulance to Landspitali University Hospital in Reykjavík Introduction: A good outcome of patients presenting with STEMI (ST-Segment Elevation Myocardial Infarction) depends on early restoration of coronary blood flow. Pre-hospital fibrinolysis is recommended if primary percutaneous coronary intervention (PPCI) cannot be performed within 90 minutes of first medical contact (FMC). The purpose of this study was to study transport times for patients with STEMI who were transported with air-ambulance from the northern rural areas of lceland to Landspitali University Hospital in Reykjavík, and to assess if the medical management was in accordance with clinical guidelines. Materials and methods: Retrospective chart review identified 33 patients with STEMI who were transported with air-ambulance to Landspitali University Hospital in Reykjavík during the years 2007 and 2008. Results: The total time from first medical contact to arrival at Landspitali University Hospital emergency room was 3 hours and 7 minutes (median). All patients received aspirin and 26 (78.8%) received clopidogrel and enoxaparin. 16 patients (48.5%) received thrombolytic therapy in median 33 minutes after FMC and 15 patients had PPCI performed in median 4 hours and 15 minutes after FMC. Estimated PCI related delay was 3 hours and 42 minutes (median). One patient died and one was resuscitated within 30 hospital days. Mean hospital stay was 6.0 days. Conclusions: First medical contact to balloon time of less than 90 minutes is impossible for patients with STEMI transported from the northern rural areas to Landspitali University Hospital in Reykjavik. Medical therapy was in many cases suboptimal and PCI related delay too long. Sigmundsson TS, Gunnarsson B, Benediktsson S, Gunnarsson GT, Duason S, Thorgeirsson G. Management of patients with STEMI transported with air-ambulance to Landspitali University Hospital in Reykjavík. Icel Med J 2010; 96: 159-65 Keywords: Air-ambulance transport, rurat medicine, myocardial infarction, fibrinolysis, quality of care. Correspondence: Þórir Svavar Sigmundsson, thorir.sigmundsson@karolinska.se Barst: 18. september 2009, - samþykkt til birtingar: 11. janúar 2010 Hagsmunatengsl: Engin LÆKNAblaðið 2010/96 165 ENGLISH SUMMARY

x

Læknablaðið

Direkte link

Hvis du vil linke til denne avis/magasin, skal du bruge disse links:

Link til denne avis/magasin: Læknablaðið
https://timarit.is/publication/986

Link til dette eksemplar:

Link til denne side:

Link til denne artikel:

Venligst ikke link direkte til billeder eller PDfs på Timarit.is, da sådanne webadresser kan ændres uden advarsel. Brug venligst de angivne webadresser for at linke til sitet.