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Læknablaðið - 01.06.2015, Blaðsíða 15

Læknablaðið - 01.06.2015, Blaðsíða 15
LÆKNAblaðið 2015/101 303 R a n n S Ó k n ENgLISH SUMMArY introduction: Symptoms of choledocholithiasis can appear after cholecystectomy. Stones diagnosed during the first two years following surgery are assumed to have been present at the time of surgery. The purpose of this study was to study patients who presented with choledocholithiasis at Landspitali - The National University Hospital of Iceland, during the period 2008-2011, who had previously undergone cholecystecomy and to assess whether cholodocholithiasis is underdi- agnosed at the time of cholecystectomy. Material and methods: The study was retrospective, data was collec- ted from medical records at Landspitali. Among recorded data were liver function tests, imaging results, time from surgery to diagnosis, treatment and complications. Results: Forty patients presented with choledocholithiasis after previous cholecystectomy. Mean age was 50 years (20-89) and women were 24 (60%). Mean time from surgery to diagnosis was 382 days. Diagnosis was confirmed with imaging in 35 (87.5% cases). Thirty six (90%) patients were treated with ERCP, one with PTC and one underwent open surgery. Three patients healed without treatment. Three patients developed complications from treatment. Thirty one (77.5%) had choledocholithiasis in the first 2 years following surgery. Incidence of previous choledocholithiasis, elevated bilirubin or widening of the choledochus without visible stones where similar for those diagnosed with choledocholithiasis in the first two years and those diagnosed later. Conclusion: Majority of patients are treated without surgery. Most sto- nes are diagnosed during the first two years following surgery. For the majority of cases it can not be concluded that stones should have been suspected at time of cholecystectomy. 1Department of Surgery, Landspítali - The National University Hospital, Reykjavík, Iceland, 2Faculty of Medicine, University of Iceland. key words: Choledocholithiasis, cholelithiasis, Endoscopic Retrograde Cholangiopancreatography, ERCP. Correspondence: Elsa Björk Valsdóttir, elsava@landspitali.is Choledocholithiasis after cholecystectomy at landspítali - The national University Hospital of iceland 2008-2011 Thorey Steinarsdottir1, Elsa B. Valsdottir1,2, Pall Helgi Moller1,2 1. Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology 1999; 117: 632-9. 2. Stokes CS, Krawczyk M, Lammert F. Gallstones: environ- ment, lifestyle and genes. Dig Dis 2011; 29: 191-201. 3. Völzke H, Baumeister SE, Alte D, Hoffmann W, Schwahn C, Simon P, et al. 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What symptoms does cholecystectomy cure? Insights from an outcomes measurement project and review of the literature. Am J Surg 1995; 169: 533-8. 10. Girometti R, Brondani G, Cereser L, Como G, Del Pin M, Bazzocchi M, et al. Post-cholecystectomy syndrome: spectrum of biliary findings at magnetic resonance cholangiopancreatography. Brit J Radiol 2010; 83: 351-61. 11. Greenfield LJ (ed). Surgery: Scientific Principles and Practice. Lippincott-Raven, Fíladelfíu 1997. 12. Arnarson A, Hauksson H, Marteinsson VT, Albertsson SM, Datye S. Gallblöðrunám með kviðsjártækni. Fyrstu 400 tilfellin á FSA. Læknablaðið 2003; 89: 35-40. 13. Viktorsdóttir O, Blöndal S, Magnússon J. Tíðni alvarlegra fylgikvilla gallkögunar. Læknablaðið 2004; 90: 487-90. 14. Videhult P, Sandblom G, Rudberg C, Rasmussen IC. Are liver function tests, pancreatitis and cholecystitis predictors of common bile duct stones? Results of a pro- spective, population-based, cohort study of 1171 patients undergoing cholecystectomy. HPB (Oxford) 2011; 13: 519- 27. 15. Parra-Membrives P, Diaz-Gomez D, Vilegas-Portero R, Molina-Linde M, Gomez-Bujedo L, Lacalle-Remigio JR. Appropriate management of common bile duct stones: a RAND Corporation/UCLA Appropriateness Method statistical analysis. Surg Endoscopy 2010; 24: 1187-94. 16. Möller M, Gustafsson U, Rasmussen F, Persson G, Thorell A. Natural Course vs Interventions to Clear Common Bile Duct Stones: Data From the Swedish Registry for Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography (GallRiks). JAMA Surg 2014; 149: 1008-13. 17. Ford JA, Soop M, Du J, Loveday BP, Rodgers M. Systematic review of intraoperative cholangiography in cholecystectomy. Brit J Surg 2012; 99: 160-7. 18. Sajid MS, Leaver C, Haider Z, Worthington T, Karanjia N, Singh KK. Routine on-table cholangiography during cholecystectomy: a systematic review. Ann R Coll Surg Engl 2012; 94: 375-80. 19. Navaneethan U, Konjeti R, Venkatesh PG, Sanaka MR, Parsi MA. Early precut sphincterotomy and the risk of endoscopic retrograde cholangiopancreatography related complications: An updated meta-analysis. World J Gastrointest Endosc 2014; 6: 200-8. 20. Liu Y, Su P, Lin S, Xiao K, Chen P, An S, Zhi F, Bai Y. Endoscopic papillary balloon dilatation versus endoscopic sphincterotomy in the treatment for choledocholithiasis: a meta-analysis. J Gastroenterol Hepatol 2012; 27: 464-71. Heimildir

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