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Læknablaðið - 01.06.2022, Blaðsíða 29

Læknablaðið - 01.06.2022, Blaðsíða 29
L ÆKNABL AÐIÐ 2022/108 297 R A N N S Ó K N Greinin barst til blaðsins 9. febrúar 2022, samþykkt til birtingar 3. maí 2022. Heimildir 1. Arciniegas DB. Psychosis. Continuum (Minneap Minn) 2015; 21: 715-36. 2. Pagsberg AK. Schizophrenia spectrum and other psychotic disorders. Eur Child Adolesc Psychiatry 2013; 22 Suppl 1: S3-9. 3. Saha S, Chant D, Welham J, et al. A systematic review of the prevalence of schizophrenia. PLoS Med 2005; 2: e141. 4. Cheng SC, Schepp KG. Early Intervention in Schizophrenia: A Literature Review. Arch Psychiatr Nurs 2016; 30: 774-81. 5. Millan MJ, Fone K, Steckler T, et al. Negative symptoms of schizophrenia: clinical charact- eristics, pathophysiological substrates, experimental models and prospects for improved treatment. Eur Neuropsychopharmacol 2014; 24: 645-92. 6. Jin H, Mosweu I. The Societal Cost of Schizophrenia: A Systematic Review. Pharmacoeconomics 2017; 35: 25-42. 7. Mueser KT, McGurk SR. Schizophrenia. Lancet 2004; 363: 2063-72. 8. 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Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis A Systematic Review, Meta-analysis, and Meta-regression. Jama Psychiatry 2018; 75: 555-65. 14. Penttilä M, Jääskeläinen E, Hirvonen N, et al. Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2014; 205: 88-94. 15. Upplýsingarit - Laugarásinn meðferðargeðdeild. Landspítali, Reykjavík 2021. 16. Koletsi M, Niersman A, van Busschbach JT, et al. Working with mental health problems: clients' experiences of IPS, vocational rehabilitation and employment. Soc Psychiatry Psychiatr Epidemiol 2009; 44: 961-70. 17. Santesteban-Echarri O, Paino M, Rice S, et al. Predictors of functional recovery in first-epis- ode psychosis: A systematic review and meta-analysis of longitudinal studies. Clin Psychol Rev 2017; 58: 59-75. 18. Tsang HW, Leung AY, Chung RC, et al. 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Schizophr Res 2010; 116: 27-34. 32. Secher RG, Hjorthøj CR, Austin SF, et al. Ten-year follow-up of the OPUS specialized early intervention trial for patients with a first episode of psychosis. Schizophr Bull 2015; 41: 617-26. 33. Atvinnuþátttaka er meiri og atvinnuleysi minna meðal þeirra sem hafa meiri menntun. Hagstofan 2015. hagstofa.is/utgafur/frettasafn/menntun/mannfjoldi-eftir-menntunar- stodu-2014/ - apríl 2021. 34. Henkel D. Unemployment and substance use: a review of the literature (1990-2010). Curr Drug Abuse Rev 2011; 4: 4-27. 35. Jónsson AJ, Birgisdóttir H, Sigurðsson E. Eykur notkun kannabis hættu á geðrofi og þróun geðklofa? Læknablaðið 2014; 100: 443-51. E N G L I S H S U M M A R Y Ragna Kristín Guðbrandsdóttir1 Oddur Ingimarsson1,2 1University of Iceland, Faculty of Medicine 2Mental Health Services, Landspítali University Hospital of Iceland. Correspondence: Oddur Ingimarsson, odduri@landspitali.is Key words: First episode psychosis, schizophrenia spectrum disorders, early intervention psychosis, employment, vocational predictors, cannabis. Functional recovery after first episode psychosis rehabilitation in an early intervention psychosis center in Iceland BACKGROUND: Because of the early onset and disabling symptoms of schizophrenia spectrum disorders many individuals with these disorders are unemployed from an early age and disability pension rates are high. The aim of this study was to assess functional recovery and identify vocational predictors among young first episode psychosis patients registered in an early intervention psychosis center in Iceland in 2010-2020. METHODS: The study is a retrospective cohort study based on the medical records of those who were discharged from Laugaras, the only early intervention psychosis program in Iceland after six months or longer rehabilitation in 2010-2020 (n=144). Univariate and multivariate logistic regression was used to identify vocational predictors. RESULTS: 75% of patients were unemployed at admission to the early intervention center but over half of the patients were employed or in school at discharge. Vocational rehabilitation was the strongest vocational predictor (OR 13.93, 95% CI 3.85-63.89). Other vocational predictors were those that reflect a disabling psychiatric disorder and social functioning before the onset of early intervention. 66% of patients had a history of cannabis use which had a negative impact on employment and education at discharge. CONCLUSIONS: In spite of intensive rehabilitation at an early intervention center, almost half of the patients were neither employed nor in school at discharge. The strongest vocational predictor was vocational rehabilitation which was also one of few vocational predictors that can be influenced by admission to an early intervention psychosis center. It therefore seems important to ensure that effective vocational rehabilitation is readily available at early intervention psychosis centers. doi 10.17992/lbl.2022.06.695

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