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Læknablaðið - 15.03.1996, Qupperneq 20

Læknablaðið - 15.03.1996, Qupperneq 20
210 LÆKNABLAÐIÐ 1996; 82 brottnámsaðgerð á eista eingöngu læknast 90- 95% sjúklinga með staðbundinn sjúkdóm. Sjúklingar með meinvörp svara flestir (yfir 90%) meðferð með krabbameinslyfjum eða geislum og 90% þeirra lifa án sjúkdóms í fjögur ár frá greiningu (18). Geisla- og lyfjameðferð hafa ýmsa fylgikvilla, meðal annars aukna tíðni krabbameina síðar á ævinni og ófrjósemi. Við teljum að aukið hlutfall yngri karla og hugsan- lega lægri stigun auki á mikilvægi þess að beita meðferð með sem fæstum fylgikvillum. Þakkir Þakkir fyrir veitta aðstoð fá Egill Jacobsen, Sverrir Haraldsson og Ólafur Örn Arnarson, yfirlæknar á þvagfæraskurðdeildum Landspít- ala, Borgarspítala og Landakotsspítala. Einnig fær Þórarinn Sveinsson yfirlæknir á krabba- meinslækningadeild Landspítala sérstakar þakkir, og sömuleiðis Shree Datye yfirlæknir á skurðdeild Fjórðungssjúkrahússins á Akur- eyri, Þorsteinn Gíslason sérfræðingur á Landa- kotsspítala, Jóhann Heiðar Jóhannsson meina- fræðingur, Helgi Sigvaldason verkfræðingur og starfsmenn Krabbameinsskrár Krabba- meinsfélas íslands. Jónas Magnússon prófess- or las greinina í handriti og eru honum þakkað- ar góðar ábendingar. Styrkir til rannsóknar- innar fengust úr tveimur sjóðum: Vísindasjóði Landspítalans og Rannsóknarstofu Háskólans og Minningarsjóði Bergþóru Magnúsdóttur og Jakobs J. Bjarnasonar. HEIMILDIR 1. Brodsky GL. Pathology of testicular germ cell tumors. Hematol/Oncol Clin North Am 1991; 5: 1095-126. 2. Catalona WJ. Current management of testicular tumors. Surg Clin North Am 1982; 62: 1119-27. 3. Ársskýrsla Krabbameinsfélags fslands 1994. Reykjavík: Krabbameinsfélag fslands, 1994. 4. Tulinius H, Storm HH, Pukkala E, Andersen A, Er- icsson J. Cancer in the Nordic Countries, 1981-86. A joint publication of the five Nordic cancer registries, 1992; 100/SuppI. 31: 88-9. 5. Parkin DM, Muir CS, Whelan SL. Cancer incidence in five continents. Vol. VI. International agency for re- search on cancer. Lyon: WHO, 1992. 6. Gudlaugsson E, Magnusson B, Hallgrimsson J. Tu- mours in Iceland: 13. Malignant tumours of the testis. APMIS 1990; 98: 173-8. 7. Fraley EE, Lange PH, Kennedy BJ. Germ-cell testicular cancer in adults. Part II. N Engl J Med 1979; 301:1420-6. 8. Boden G, Gibb R. Radiotherapy and testicular neo- plasms. Lancet 1951; 2: 1195-7. 9. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Ass 1958; 53: 457- 81. 10. Taron RE. Test for trend in lifetable anaiysis. Biometr- ika 1975; 62: 679-82. 11. Harpold C, JubelirerSJ. Seminoma: areviewof 15 years experience. West Virg Med J 1991; 87: 148-51. 12. Kennedy BJ, Schmidt JD, Winchester DP, Peace BL, Natarajan N, Mettlin C. National survey of patterns of care for testis cancer. Cancer 1987; 60: 1921-30. 13. Schultz HP, Arends J. Barlebo H, Brincker H, Stryer CI, Engelholm SA, et al. Testicular carcinoma in Den- mark 1976-1980. Stage and selected clinical parameters at presentation. Acta Rad Oncol 1984; 23: 249-53. 14. Hemdal K, Fossá SD, Johansen A. Increasing incidence and changing stage distribution of testicular carcinoma in Norway 1970-1987. Br J Cancer 1990; 62: 277-8. 15. Osterlind A. Testikelcancer i Danmark 1943-1982. Kræftstatistik nr. 14. Ugeskr Læger 1986; 148: 418-21. 16. Whitaker RH. Management of the undescended testis. Brit J Hosp Med 1970; 4: 25-37. 17. Moul JW. Paulson DF, Dodge RK, Walter PJ. Delay in diagnosis and survival in testicular cancer: Impact of effective therapy and changes during 18 years. J Urol 1990; 143: 520-3. 18. Richie JP. Neoplasms of the testis. In: Walsh PC, ed. Campbell’s Urology. 6th ed. Pennsylvania: Saunders, 1992: 1222-63. 19. Erichsen A. Testikulære germinalcellesvulster - epide- miologi og risikofactorer. Tidsskr Nor Lægeforen 1990; 110: 2541-3. 20. Babaian RJ, Zagars G. Testicularseminoma: The M.D. Anderson experience. An analysis of pathological and patient characteristics, and treatment recommenda- tions. J Urol 1988; 139: 311-4. 21. Upplýsingarfrá Krabbameinsfélagi fslands,janúar 1995. 22. Thomas GM. Rider WD, Dembo AJ, Cummings BJ, Gospodarowicz M. Hawkins NV, et al. Seminoma of the testis: results of treatment and patterns of failure after radiation therapy. Int J Radiat Oncol Biol Phys 1982; 8: 165-74. 23. van der Werf-Messing B. Radiotherapeutic treatment of testicular tumors. Int J Radiat Oncol Biol Phys 1976; 1: 235^18. 24. Green N, Broth E, George FW, Kaplan R. Lombardo L, Skaist L. Radiation therapy in bulky seminoma. Urology 1983; 21: 467-9. 25. Richie JP. Surgical aspects in the treatment of patients with testicular cancer. Hematol/Oncol Clin North Am 1991; 5: 1127^12. 26. Pillary G, Rubenstein WA, Siess J. Seminoma. Im- próved imaging and tumor characterization with com- puted tomography. J Urol 1980; 123: 41-3. 27. Williams RD, Feinberg SB, Knight LC, Fraley EE. Ab- dominal staging of testicular tumors using ultrasonog- raphy and computed tomography. J Urol 1980; 123: 872-5. 28. Dahl O. Testicular carcinoma. A curable malignancy. Acta Radiol Oncol 1985; 24: 3-15. 29. Einhorn LH, Williams SD. Chemotherapy of dissemi- nated testicular cancer, a random prospective study. Cancer 1980; 46: 1339^14. 30. Duchene GM, Horwich A, Dearnaley DP, Nicholls J, Jay G, Peckham MJ, et al. Orchidectomy alone for stage I seminoma of the testis. Cancer 1990; 65: 1115-8. 31. Thomas GM. Surveillance in stage I seminoma of the testis. Urol Clin North Am 1993; 20: 85-91. 32. Jacobsen GK, Mellemgaard A, Möller H. Increased incidence of sarcoma in patients treated for testicular seminoma. Eur J Cancer 1993; 29A(5): 664-8. 33. Drasga RE, Einhorn LH. Williams SD. Patel DN, Ste- vens EE. Fertility after chemotherapy for testicular can- cer. J Clin Onc 1983; 179-83.
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