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Læknablaðið - 15.08.1996, Page 45

Læknablaðið - 15.08.1996, Page 45
LÆKNABLAÐIÐ 1996; 82 591 cian-rated clinical outcome variables do not necessary measure the patient’s QoL. Clinical and demographic variables were in the long run stronger predictors than patients’ self-as- sessments, but the QoL measures added unique information. The psychometric analy- ses of the QLQ-C36 confirmed good face and internal validity, reliability, construct and ex- ternal validity, responsiveness over time and ability to differentiate between clinical sub- groups of patients. The same held true for the study-specific MM module. Despite perceived burden of treatment, very few patients re- vealed thoughts about treatment. They valued treatment and communicated mostly with their family about side effects. Attending nurses both over- and underestimated several aspects of the patient’s QoL while relatives seemed to be more adequate proxy raters. The nursing staff was equally eager to treat and receive treatment as the doctors. The staff found their work meaningful and rewarding. Conclusions: The EORTC QLQ is applica- ble in patients with generalised malignant mel- anoma on chemotherapy, seems clinically rele- vant and adds information beyond the tradi- tional biomedical parameters. Despite pessimistic results and perceived burden of treatment both patients and personnel advo- cated chemotherapy.

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