Læknablaðið - dec. 2019, Side 33
LÆKNAblaðið 2019/105 569
Y F I R L I T
Barst til blaðsins 14. maí 2019, samþykkt til birtingar 14. október 2019.
Gastrointestinal bleeding is a common cause for presentation in
the emergency room and hospitalization. The bleeding is usually
categorized to upper or lower gastrointestinal bleeding. The purpose
of this review article is to provide an overview of the incidence of
gastrointestinal bleeding, etiology, risk factors, role of antithrombot-
ics, evaluation of the severity of bleeding, therapy and outcome.
Emphasis will be put on gastrointestinal bleeding within the Icelandic
health care system but also in broader terms.
Gastrointestinal bleeding in Iceland and in broader terms – a review
ENGLISH SUMMARY
1Division of Medical Gastroenterology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Faculty of Medicine, University of
Iceland, Reykjavík, Iceland, 3Division of Gastroenterology and Hepatology, Department of Internal Medicine, The National University Hospital of Iceland, Reykjavík,
Iceland.
Key words: Gastrointestinal haemorrhage, GI bleeding overview, Antithrombotic therapy, GIB risk evaluation.
Correspondence: Jóhann P. Hreinsson, hreinssonjp@gmail.com
Jóhann P. Hreinsson1
Einar S. Björnsson 2,3
DOI: 10.17992/lbl.2019.12.262
62. Chavez-Tapia N, Barrientos-Gutierrez T, Tellez-Avila
F, Soares-Weiser K, Mendez-Sanchez N, Gluud C, et al.
Meta-analysis: antibiotic prophylaxis for cirrhotic pati-
ents with upper gastrointestinal bleeding–an updated
Cochrane review. Alim Pharmacol Therap 2011; 34: 509-
18.
63. Hreinsson K, Guðmundsson S, Steingrímsdóttir H,
Birgisson G, Jóhannesson A. Klínískar leiðbeiningar
um notkun blóðhluta á Landspítala. Landspítali,
Reykavík 2012. landspitali.is/library/Sameiginlegar-skrar/
Gagnasafn/BRUNNURINN/Kliniskar-leidbeiningar/
Blodhlutar/klin_leid_notkun_blodhluta_sept_2012.pdf -
apríl 2019.
64. Jairath V, Kahan BC, Gray A, Dore CJ, Mora A, James MW,
et al. Restrictive versus liberal blood transfusion for acute
upper gastrointestinal bleeding (TRIGGER): a pragmatic,
open-label, cluster randomised feasibility trial. Lancet
2015; 386: 137-44.
65. Villanueva C, Colomo A, Bosch A, Concepcion M,
Hernandez-Gea V, Aracil C, et al. Transfusion strategies
for acute upper gastrointestinal bleeding. N Engl J Med
2013; 368: 11-21.
66. Sung JJ, Lau JY, Ching JY, Wu JC, Lee YT, Chiu PW, et al.
Continuation of low-dose aspirin therapy in peptic ulcer
bleeding: a randomized trial. Ann Intern Med 2010; 152:
1-9.
67. Oakland K, Chadwick G, East JE, Guy R, Humphries A,
Jairath V, et al. Diagnosis and management of acute lower
gastrointestinal bleeding: guidelines from the British
Society of Gastroenterology. Gut 2019: gutjnl-2018-317807.
68. Green BT, Rockey DC, Portwood G, Tarnasky PR, Guarisco
S, Branch MS, et al. Urgent colonoscopy for evaluation and
management of acute lower gastrointestinal hemorrhage:
a randomized controlled trial. Am J Gastroenterol 2005;
100: 2395.
69. Hreinsson JP, Ægisdottir S, Bjornsson ES. Acute
lower gastrointestinal bleeding: A population-based
five-year follow-up study. Un Eur Gastroenterol J
2019;2050640619863517.
70. Hreinsson JP, Bjarnason I, Bjornsson ES. The outcome and
role of drugs in patients with unexplained gastrointestinal
bleeding. Scand J Gastroenterol 2015; 50: 1482-9.
Leiðrétting
Í greinina Hæðarveiki og tengdir sjúkdómar í nóvemberblaðinu
(Læknablaðið 2019; 105: 499-507) vantaði því miður eina töflu
við birtingu og upplýsingar á mynd 3 voru ekki réttar. Beðist er
velvirðingar á þessari handvömm, þetta hefur verið leiðrétt á
netinu og í nýjum pdf.