Læknablaðið - 15.09.1993, Blaðsíða 17

LÆKNABLAÐIÐ
269
háþrýstingsbundin eða sýkursýkisháð skemmd
á hjartanu.
ÞAKKIR
Færum starfsfólki Rannsóknarstöðvar
Hjartaverndar þakkir fyrir margvíslega
aðstoð, sérstakar þakkir fær Elínborg
Sveinbjarnardóttir fyrir aðstoð við gerð mynda
og taflna.
SUMMARY
This study is based on the Reykjavík Study, a long-
term prospective cardiovascular survey including a
representative population of 9.135 men and 9.627
wornen, 33-79 years old, who were invited to
participate in a cohort study during the years 1967-
91.
Right bundle branch block (RBBB) was found in
126 men and 67 women. The prevalence increased
with age, from 0% among men and women 30-
39 years of age to 4.1% (men) and 1.6% (women)
75-79 years old. The incidence increased with
age among men and women. In men younger
than sixty RBBB had a significant relation to
hypertension (p<0.05), elevated fasting blood
glucose (p=0.05) and increased heart size (p<0.05).
In men with RBBB regardless of age, association
was found with ischemic heart disease (p<0.05),
arrhythmias (p<0.001) and bradycardia (p<0.01).
Higher mortality from heart disease (p<0.01) was
found in men with RBBB compared to the control
population. This was not significant when risk
factors of heart disease were taken into account
by multivariate Cox analysis. There was relation
(p<0.05) between hypertension and RBBB in
women younger than sixty.
RBBB in women younger than sixty is often
associated with hypertension and in men younger
than sixty RBBB is often associated with an
underlying cardiovascular disease, hypertension,
cardiomegaly and elevated blood glucose.
HEIMILDIR
1. Eppinger H. Rothberger CJ. Zur Analyse des
Elektrokardiogramms. Wiener klin Wochenschrift
1909; 22: 1091-8.
2. Wilson FN, Macleod AG, Barker PS. The Order
of Ventricular Excitation in Human Bundle-branch
Block. Am Heart J 1932; 7: 305-30.
3 Barrelt PA, Thomas PC, Swan HJC, Singh BN,
Mandcl WJ. The Frequency and Prognostic
Significance of Electrocardiographic Abnormalities in
Clinically Normal Individuals. Progress in Cardiovasc
Dis 1981; 23: 299-319.
4. Vazifdar JP, Levine SA. Benign Bundle Branch
Block. Arch Intem Med 1952; 89: 568-74.
5. Messer AD. Johnson RP, Shreenivas, White PD.
Prognosis in Bundle Branch Block III. A Comparison
of Right and Left Bundle Branch Block With a Note
on the Relative Incidence of Each. Am Heart J 1951;
41: 239-45.
6. Smith RF, Jackson DH, Harthome JW, Sanders
CA. Acquired bundle branch block in a healthy
population. Am Heart J 1970; 80: 746-51.
7. Wood FC, Jeffers WA, Wolferth CC. Follow-up Study
of Sixty-four Patients with a Right Bundle-branch
Conduction Defect. Am Heart J 1935; 10: 1056-66.
8. Kreger BE, Anderson KM, Kannel WB. Prevalence
of intravenlricular block in the general population:
The Framingham Study. Am Heart J 1989; 117: 903-
10.
9. Ostrander LD, Brandt RL. Kjelsberg MO, Epstein
FH. Electrocardiographic Findings Among the Adult
Population of a Total Natural Community, Tecumseh,
Michigan. Circulation 1965; XXXI: 888-98.
10. Schneider JF, Thomas HE, Sorlie P, Kreger BE,
McNamara PM, Kannel WB. Comparative Features
of Newly Acquired Left and Right Bundle Branch
Block in the General Population: The Framingham
Study. Am J Cardiol 1981; 47: 931-40.
11. Björnsson OJ, Davidsson D, Olafsson O, Sigfússon
N, Thorsteinsson Th. Report ABC XVIII. Health
survey in the Reykjavík area. Males. Stages I-
III, 1967-68, 1970-71 and 1974-76. Participants,
invitations, responses etc. Reykjavík: Hjartavemd,
1979.
12. Björnsson G. Bjömsson OJ, Davidsson D, et al.
Report abc XXIV. Health survey in the Reykjavik
area. Women. Stages I-III, 1968-69, 1971-72 and
1976-78. Participants. invitations etc. Reykjavík:
Hjartavemd, 1982.
13. Amason A, Pálsson K, Harðarson Þ, Eyjólfsson
K, Sigfússon N. Vinstra greinrof á Islandi I.
Læknablaðið 1985; 71: 3-8.
14. Þorgeirsson G. Davíðsson D, Sigvaldason H,
Sigfússon N. Áhættuþættir kransæðasjúkdóms
meðal karla og kvenna á Islandi. Niðurstöður úr
hóprannsókn Hjartavemdar 1967-1985. Læknablaðið
1992; 78: 267-76.
15. Sigfússon N, Sigvaldason H, Guðmundsdótlir
II, et al. Breytingar á tíðni kransæðastíflu og
kransæðadauðsfalla á Islandi. Tengsl við áhættuþætti
og mataræði. Læknablaðið 1991, 77: 49-58.
16. Rose GA, Blackburn H. Cardiovascular survey
methods. Geneva: World Health Organization, 1968.
17. Colton T. Stalistics in medicine. Ist ed. Boston:
Little, Brown and Company, 1974.
18. Dixon WT. Brown MB. Engelman L, et al. BMDP
Statistical Software Manual. Berklcy: University of
Califomia Press, 1985.
19. Cox DR. Regression models and life tables. J Stat
Soc 1972; 34 (SeriesB): 187-220.
20. Önundarson PT, Thorgeirsson G, Jonmundsson E,
Sigfússon N, Hardarson Th. Chronic atrial fibrillation
- epidemiologic features and 14 year follow-up: A
case control study. Eur Heart J 1987; 8: 521-7.
21. Lev M, Ungcr PN, Lesser ME, Pick A. Pathology
of the conduction system in acquired heart disease.
Complete right bundle branch block. Am Heart J
1961;61: 593-614.
22. Lenegre J. Etiology and Pathology of Bilateral
Bundle Branch Block in Relalion to Complete Heart
Block. Prog Cardiovasc Dis 1964; 6: 409-44.
23. Frohlich ED. Apstein C, Chobanian AV, et al. The
heart in hypertension. N Engl J Med 1992; 327: 998-
1008.