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Læknablaðið - 15.10.1997, Side 43

Læknablaðið - 15.10.1997, Side 43
LÆKNABLAÐIÐ 1997; 83 663 temporal oxygen metabolism in Alzheimer’s disease shown by PET. J Nucl Med 1996; 37: 1159-65. 21. Simonian NA, Coyle JT. Oxidative Stress in Neurode- generative Diseases. Ann Rev Pharmacol Toxicol 1996; 36: 83-106. 22. Davis RE, Miller S, Herrnstadt C, Ghosh SS, Fahy E, Shinobu LA, et al. Mutation in mitochondrial cyto- chrome c oxidase genes segregate with late-onset Alz- heimer disease. Proc Natl Acad Sci 1997; 94: 4526-31. 23. Sandbrink R, Hartmann T, Masters CL, Beyreuther K. Genes contributing to Alzheimer’s disease. Mol Psychi- atry 1996; 1: 27-40. 24. Muramatsu T, Matsushita S, Arai H, Sasaki H, Higuchi S. Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer’s disease. J Neural Transm 1996:103: 1205-10. 25. Schofield PW, Tang M, Marder K, Bell K, Dooneief G, Chun M, et al. Alzheimer's disease after remote head injury: an incidence study. J Neurol Neurosurg Psychia- try 1997; 62: 119-24. 26. Savory J, Exley C, Forbes WF, Huang Y, Joshi JG, Kruck T, et al. Can the controversy of the role of alu- minium in Alzheimer’s disease be resolved? What are the suggested approaches to this controversy and meth- odological issues to be considered? J Toxicol Environ Health 1996; 48: 615-35. 27. Tanzi RE. Neuropathology in the Down’s Syndrome Brain. Nat Med 1996; 2: 31-2. 28. Wilson DM, Binder LI. Free Fatty Acids Stimulate the Polymerization of Tau and Amyloid (3 Peptides. In Vitro Evidence for a Common Effector of Pathogenesis in Alzheimer’s Disease. Am J Pathol 1997; 150: 2181-95. 29. Saitoh T, Mook-Jung I. Commentary: Is Understanding the Biological Functions of APP Important in Under- standing Alzheimer’s Disease? Alzheimer’s Dis Rev 1996; 1: 30-6. 30. Connor B, Young D, Lawlor P, Gai W, Waldvogel H, Faull RL, et al. Trk receptor alteration in Alzheimer’s disease. Brain Res Mol Brain Res 1996; 42: 1-17. 31. Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacaná E, Sunderland T, et al. Participation of Presenilin 2 in Apoptosis: Enhanced Basal Activity Conferred by an Alzheimer Mutation. Science 1996; 274: 1710-3. 32. McShea A, Harris PLR, Webster KR, Wahl AF, Smith MA. Short Communication: Abnormal Expression of the Cell Cycle Regulators P16 and CDK4 in Alzheimer’s Disease. Am J Pathol 1997; 150: 1933-9. 33. O’Barr S, Schultz J, Rogers J. Expression of the pro- tooncogene bcl-2 in Alzheimer’s Disease. Neurobiol Ageing 1996; 17: 131-6. 34. Neve R. Amyloid Discussion Group: APP and Signall- ing. Harvard Medical School, 1996: http://www. alzforum.org/members/forums/amyloid/signalling.html 35. Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, et al. Mutant presenilins of Alzheimer’s disease increase production of 42-residue amyloid beta- protein in both transfected cells and transgenic mice. Nat Med 1997; 3: 67-72. 36. Illingworth RD. Lipoprotein Metabolism. Am J Kidney Disease 1993; 22: 90-7. 37. Mahley RW. Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology. Science 1988; 240: 622-30. 38. Payami H, Zareparsi S, Montee KR, Sexton GJ, Kaye JA, Bird TD, et al. Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a pos- sible clue to the higher incidence of Alzheimer’s disease in women. Am J Hum Genet 1996; 58: 803-11. 39. Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and Atherosclerosis. Arteriosclerosis 1988; 8: 1-21. Enskt íslenskt orðasafn A|3 (amyloid (3-peptide) = amýloid beta peptíð ACT-A (antichymotrypsin A) = andkýmó- trýpsín A ApoE (apolipoprotein E) = apólípóprótín E App ((3-amyloid precursor protein) = (3-amýl- oid forveraprótín C100 (C-end of App) = innanfrumuhluti (C- endi) App FAD (familial Alzheimer’s disease) = ættlæg- ur Alzheimers sjúkdómur GAG (glycosaminosglycan) = glýkósamínó- glýkan HLA-A (human leukocyte antigen A) = vefja- flokkasameind af gerð A LDL (low-density-lipoprotein) = lágþéttni lípóprótín MAP (microtubule associated protein) = ör- píplutengd prótín mApp (membrane-bound App) = himnu- bundið App MEKK (MAP kinase’s kinase) = MAP kínasa kínasi NFT (neurofibrillary tangles) = taugatrefja- flækjur NP (neuritic plaques) = taugaflögur Pak (p21 activated kinase) = prótín (21kD) espaður kínasi PET (positron emission tomography) = jáeindar útgeislunar sneiðmyndataka Ps (presenilin) = Ps-prótín sApp (secreted App) = seytt App VLDL-R (very-low-density-lipoprotein R) = ofurlágþéttni lípóprótín R

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