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Læknablaðið - 15.02.1994, Qupperneq 26

Læknablaðið - 15.02.1994, Qupperneq 26
68 LÆKNABLAÐIÐ oft sársaukafullar fyrir börn, auka hættu á þvagfærasýkingu vegna ýmissa aðgerða (blöðrumynd og blöðruspeglun) og valda auk þess foreldrum fjárhagslegu tjóni vegna fjarveru frá vinnu. Því ber læknum að vanda vel til þvagsýnatöku hjá ungum börnum og staðfesta þvagfærasýkingu, annað hvort með ástungu- eða þvagleggsþvagi. SUMMARY Urinary tract infections in infants are common. Unrecognized and untreated infections can have serious consequences to the kidneys and can cause serious diseases later in life. Urine specimens are often obtained by adhesive bags in young children and infants. The purpose of this study is to explore the diagnostic value of urinary bag specimens in diagnosing urinary tract infection in infants. One hundred infants were studied prospectively at the Pediatric Department of the University Hospital in Iceland regardless of underlying diagnosis. Urinary tract infection was confirmed in 7 children by either a supra-pubic aspirate or a catheter specimen. Thirty children had contaminated bag specimens. Mulitvariate regression analysis revealed that microscopic bacterial and white blood cell count correlated best with urinary tract infection (r: 0.42 and r2 change: 0.15 respectively, p< 0.05) but a culture of the bag specimen correlated poorly ( r2 change: 0.03, p<0.05). Using bacterial count of 100.000 per ml. in a bag specimen as a cut off value, had a positive predictive value of only 46% but a negative predicive value of 99%. It is concluded that a bag specimen cannot be used reliably in diagnosing urinary tract infection in infants. A properly collected urine by either a supra-pubic aspirate or a catheter should be used for diagnostic purposes. HEIMILDIR 1. Winberg J, Andersen H, Bergström T, et al. Epidemiology of symptomatic urinary tract infection in childhood. Acta Paediatr Scand 1974; 252/Suppl. nr: 1-20. 2. McCracken GH Jr. Diagnosis and management of acute urinary tract infections in infants and children. Pediatr Infect Dis J 1987; 6: 107-12. 3. Siegel SR, Siegel B, Sokoloff BZ, et al. Urinary infection in infants and preschool children. Am J Dis Child 1980; 134: 369-72. 4. Rapkin RH. Urinary tract infection in childhood. Pediatrics 1977; 60: 508-11. 5. Jodal U. The Natural History of Bacteriuria in Childhood. Infect Dis Clin North Am 1987; 1: 713- 29. 6. Stull TL, LiPuma JJ. Epidemiology and natural history of urinary tract infections in children. Med Clin North Am 1991; 73: 287-97. 7. Smellie JM, Ransley PG, Normand ICS, et al. Development of new renal scars: A collaborative study. Br Med J 1985; 290: 1957-60. 8. Wettergren B, Jodal U, Jonasson xy. Epidemiology of bacteriuria during the first year of life. Acta Paediatr Scand 1985; 74: 925-33. 9. Haycock GB. Investigation of urinary tract. Arch Dis Child 1986; 61: 1155-8. 10. Jacobson SH, Eklof O, Eriksson CG, Lins LE, Tidgren B, Winberg J. Development of hypertension and uremia after pyelonephritis in childhood: 27 year follow up. Br Med J 1989; 299: 703-6. 11. Stork JE. Urinary tract infection in children. Adv Pediatr Infect Dis 1987; 2: 115-34. 12. Shad KJ, Robins DG, White RHR. Renal scarring and vesicoureteric reflux. Arch Dis Child 1978; 53: 210-7. 13. Rolleston GL, Maling TM, Hodson CJ. Intrarenal reflux and the scarred kidney. Arch Dis Child 1974; 49: 531-9. 14. Durbin WA JR, Peters G. Management of urinary tract infections-in infants and children. Pediatr Infect Dis J 1984; 3; 564-74. 15. Ogra PL, Faden HS. Urinary tract infections in childhood: An update. J Pediatr 1985; 106: 1023-9. 16. Edelmann CM Jr, Ogwo JE, Fine BP, Martinez AB. The prevalence of bacteriuria in full term and premature newbom infants. J Pediatr 1973; 82: 125- 32. 17. Schlager TA, Dunn ML, Dudley SM, Lohr JA. Bacterial contamination rate of urine collected in a urine bag from healthy non-toilet-trained male infants. J Pediatr 1990; 116: 738-9. 18. Sýkingavamamefnd Lsp. Leiðbeiningar um miðbunuþvagtöku. Desember 1990. 19. Friedman GD. Primer of epidemiology. 3rd ed. New York: McGraw-Hill, 1987: 261-2. 20. Cannon HJ Jr, Goetz ES, Hamoudi AC, Marcon MJ. Rapid screening and microbiologic processing of pediatric urine specimens. Diagn Microbiol Infect Dis 1986; 4: 11-7. 21. Lohr JA. Use of routine urinalysis in making a presumptive diagnosis of urinary tract infection in children. Pediatr Infect Dis J 1991; 10: 646-50. 22. Lohr JA, Portilla MG, Geuder TG, Dunn ML, Dudley SM. Making a presumptive diagnosis of urinary tract infection by using a urinalysis performed in an on- site laboratory. J Pediatr 1993; 122: 22-5. 23. Shaw KN, Hexter D, McGowen KL, Schwartz JS. Clinical evaluation of a rapid screening test for urinary tract infections in children. J Pediatr 1991; 118: 733-6. 24. Weinberg AG, Gan VN. Urine screen for bacteruria in symptomatic pediatric outpatients. Pediatr Infect Dis J 1991; 10: 651-4. 25. Aronson AS, Gustafson B. Svenningsen NW. Combined suprapubic aspiration and clean voided urine examination in infants and children. Acta Pediatr Scand 1973; 62: 396-400.

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