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Læknablaðið - 01.11.2014, Page 34

Læknablaðið - 01.11.2014, Page 34
602 LÆKNAblaðið 2014/100 S a G a l æ k n i S F R æ ð i n n a R Vísindin efla alla dáð, orkuna styrkja, viljann hvessa, vonina glæða, hugann hressa, farsældum vefja lýð og láð. Skyldur okkar sem vísindamanna eru margþættar. Hefð­ bundna háskólahlutverkið er að afla nýrrar þekkingar og miðla henni til nemenda og almennings. Nýsköpunarhlutverkið, það er að nýta vísindalega þekkingu til atvinnu­ og verðmætasköpunar, er tiltölulega nýtilkomið hér á Íslandi. Síðasta ljóðlína Jónasar: „farsældum vefja lýð og láð“ vísar kannski til þessa hlutverks vísindanna. Vísindaleg nýsköpun er ein meginundirstaða hagsældar nútímaþjóðfélaga. Bandaríska viðskiptaráðuneytið áætlar að tækniþróun og nýsköpun standi undir 75% af vexti þjóðarbúsins frá stríðslokum. Hlutverk Háskóla Íslands og okkar sem vísindamanna er meðal annars að finna og skapa tækifæri til nýsköpunar í atvinnulífi og verðmætasköpunar fyrir okkur öll. Framtíð íslensks þjóðarbús á nokkuð undir því að okkur takist vel til. 1. Machemer R. [Development of pars plana vitrectomy. My personal contribution]. Klin Monbl Augenheilkd 1995; 207: 147­61. Review. German. 2. Stefánsson E, Machemer R, de Juan E Jr, McCuen BW 2nd, Peterson J. Retinal oxygenation and laser treatment in patients with diabetic retinopathy. Am J Ophthalmol 1992; 113: 36­8. 3. Stefánsson E, Wilson CA, Schoen T, Kuwabara T. Experimental ischemia induces cell mitosis in the adult rat retina. Invest Ophthalmol Vis Sci 1988; 29:1050­5. 4. Kristinsson JK, Fridriksdóttir H, Thórisdóttir S, Sigurd­ ardóttir AM, Stefánsson E, Loftsson T. Dexamethasone­ cyclodextrin­polymer co­complexes in aqueous eye drops. Aqueous humor pharmacokinetics in humans. Invest Ophthalmol Vis Sci 1996; 37:1 199­203. 5. Tanito M, Hara K, Takai Y, Matsuoka Y, Nishimura N, Jansook P, et al. Topical dexamethasone­cyclodextrin microparticle eye drops for diabetic macular edema. Invest Ophthalmol Vis Sci 2011; 52: 7944­8 6. Jóhannesson G, Moya­Ortega MD, Asgrímsdóttir GM, Lund SH, Thorsteinsdóttir M, Loftsson T, et al. Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluid.Acta Ophthalmol 2013. doi: 10.1111/aos.12334. [Epub ahead of print] 7. Jóhannesson G, Kurkov SV, Jansook P, Loftsson T, Stefánsson E, Gudmundsdottir BS, et al. ­Cyclodextrin nanoparticle eye drops with dorzolamide: effect on intraocular pressure in man. J Ocul Pharmacol Ther 2014; 30: 35­41. 8. Jansook P, Muankaew C, Stefánsson E, Loftsson T. Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops. Pharm Dev Technol 2014. [Epub ahead of print] 9. Stefansson E, Landers MB 3rd, Wolbarsht ML. Oxygenation and vasodilatation in relation to diabetic and other proliferative retinopathies. Ophthalmic Surg 1983;14: 209­26. 10. Stefánsson E. Ocular oxygenation and the treatment of diabetic retinopathy. Surv Ophthalmol 2006; 51: 364­80. 11. Einstein A. On the Movement of Small Particles Suspended in Stationary Liquids Required by the Molecular­Kinetic Theory of Heat. Ann der Physik 1905; 17: 549­60. 12. Gisladottir S, Loftsson T, Stefansson E. Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equation. Graefes Arch Clin Exp Ophthalmol 2009; 247: 1677­84. 13. Stefánsson E, Geirsdóttir A, Sigurdsson H. Metabolic physiology in age related macular degeneration. Prog Retin Eye Res 2011; 30: 72­80. 14. Stefánsson E. Physiology of vitreous surgery. Graefes Arch Clin Exp Ophthalmol 2009; 247: 147­63. 15. Stefánsson E. Physiology of vitreous surgery. Graefes Arch Clin Exp Ophthalmol 2009; 247: 147­63. 16. Stefánsson E, Jensen PK, Eysteinsson T, Bang K, Kiilgaard JF, Dollerup J, et al. Optic nerve oxygen tension in pigs and the effect of carbonic anhydrase inhibitors. Invest Ophthalmol Vis Sci 1999; 40: 2756­61. 17. Stefánsson E, Pedersen DB, Jensen PK, la Cour M, Kiilgaard JF, Bang K, et al. Optic nerve oxygenation. Prog Retin Eye Res 2005; 24: 307­32. 18. Pedersen DB, Stefánsson E, Kiilgaard JF, Jensen PK, Eysteinsson T, Bang K, et al. Optic nerve pH and PO2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosis. Acta Ophthalmol Scand 2006; 84: 475­80. 19. Noergaard MH, Bach­Holm D, Scherfig E, Bang K, Jensen PK, Kiilgaard JF, et al. Dorzolamide increases retinal oxygen tension after branch retinal vein occlusion. Invest Ophthalmol Vis Sci 2008; 49: 1136­41. doi: 10.1167/iovs.07­ 0508. 20. Hardarson SH, Harris A, Karlsson RA, Halldorsson GH, Kagemann L, Rechtman E, et al. Automatic retinal oximetry. Invest Ophthalmol Vis Sci 2006; 47: 5011­6. 21. Hardarson SH. Retinal oximetry. Acta Ophthalmol 2013; 91 Thesis 2:1­47. doi: 10.1111/aos.12086. 22. Hardarson SH. Retinal oximetry. Acta Ophthalmol 2013; 91: 489­90. doi: 10.1111/aos.12239. 23. Traustason S, Kiilgaard JF, Karlsson RA, Hardarson SH, Stefansson E, la Cour M. Spectrophotometric retinal oximetry in pigs. Invest Ophthalmol Vis Sci 2013; 54: 2746­ 51. doi: 10.1167/iovs.12­11284. 24. Geirsdottir A, Hardarson SH, Olafsdottir OB, Stefánsson E Retinal oxygen metabolism in exudative age­related macular degeneration. Acta Ophthalmol 2014; 92: 27­33. 25. Olafsdottir OB, Vandewalle E, Abegão Pinto L, Geirsdottir A, De Clerck E, Stalmans P, et al. Retinal oxygen metabolism in healthy subjects and glaucoma patients. Br J Ophthalmol 2014; 98: 329­33. doi: 10.1136/bjop­ hthalmol­2013­303162. 26. Kristjansdottir JV, Hardarson SH, Harvey AR, Olafsdottir OB, Eliasdottir TS, Stefánsson E. Choroidal oximetry with a noninvasive spectrophotometric oximeter. Invest Ophthalmol Vis Sci 2013; 54: 3234­9. doi: 10.1167/iovs.12­ 10507. 27. Vandewalle E, Abegão Pinto L, Olafsdottir OB, Stalmans I. Phenylephrine 5% added to tropicamide 0.5% eye drops does not influence retinal oxygen saturation values or retinal vessel diameter in glaucoma patients. Acta Ophthalmol 2013; 91: 733­7. 28. Danielsen R, Jónasson F, Helgason T. Prevalence of retinopathy and proteinuria in type 1 diabetics in Iceland. Acta Med Scand 1982; 212: 277­80. 29. Kristinsson JK, Hauksdóttir H, Stefánsson E, Jónasson F, Gíslason I. Active prevention in diabetic eye disease. A 4­year follow­up. Acta Ophthalmol Scand 1997; 75: 249­54. 30. Kristinsson JK, Stefánsson E, Jónasson F, Gíslason I, Björnsson S. Screening for eye disease in type 2 diabetes mellitus. Acta Ophthalmol (Copenh) 1994; 72: 341­6. 31. Kristinsson JK, Stefánsson E, Jónasson F, Gíslason I, Björnsson S. Systematic screening for diabetic eye disease in insulin dependent diabetes. Acta Ophthalmol (Copenh) 1994; 72: 72­8. 32. Olafsdottir E, Andersson DK, Dedorsson I, Stefánsson E. The prevalence of retinopathy in subjects with and without type 2 diabetes mellitus. Acta Ophthalmol 2014; 92: 133­7. doi: 10.1111/aos.12095. 33. Olafsdottir E, Andersson DK, Stefánsson E. The preva­ lence of cataract in a population with and without type 2 diabetes mellitus. Acta Ophthalmol 2012; 90: 334­40. 34. Kristinsson JK, Gudmundsson JR, Stefánsson E, Jónasson F, Gíslason I, Thórsson AV. Screening for diabetic retino­ pathy. Initiation and frequency. Acta Ophthalmol Scand 1995; 73: 525­8. 35. Olafsdóttir E, Stefánsson E. Biennial eye screening in patients with diabetes without retinopathy: 10­year experience. Br J Ophthalmol 2007; 91: 1599­601. 36. Stefánsson E. Man versus machine: is technology a bless­ ing or a barrier in screening for diabetic eye disease? Acta Ophthalmol Scand 2004; 82: 643­4. 37. Stefánsson E, Bek T, Porta M, Larsen N, Kristinsson JK, Agardh E. Screening and prevention of diabetic blindness. Acta Ophthalmol Scand 2000; 78: 374­85. 38. Aspelund T, Thornórisdóttir O, Olafsdottir E, Gud­ mundsdottir A, Einarsdóttir AB, Mehlsen J, et al. Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy. Diabetologia 2011; 54: 2525­32. doi: 10.1007/s00125­011­ 2257­7. Heimildir & Victoza (líraglútíð) leiðir til allt að:1 1,5% lækkunar á HbA1c frá 8,4 % HbA1c til 6,9 % HbA1c 3,7 kg þyngdartaps Magi Victoza seinkar magatæmingu og veitir því aukna mettunartilnningu. 2,3 Briskirtill Victoza virkjar betafrumurnar sem losa insúlín þegar blóðsykur er hár. 2,3 Lifur Victoza hamlar seytingu glúkagons og dregur úr útskilnaði glúkósa frá lifur. 2,3 Matarlyst Victoza dregur úr matarlyst, sem leiðir til minnkaðrar fæðuneyslu. 2 líraglútíð Staða sérfræðilæknis og deildarlæknis SÁÁ auglýsir lausar til umsóknar stöður sérfræðilæknis og deildarlæknis á Sjúkrahúsinu Vogi. Nánari upplýsingar veitir Þórarinn Tyrfingsson í síma 824 7600, thorarinn@saa.is

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