Læknablaðið - 15.02.1991, Blaðsíða 29

LÆKNABLAÐIÐ
65
Hér var aðeins um að ræða greiningu virkra
efna í einni náttúruvöru, og hvorki var leitast
við að greina aukaefni né utanaðkomandi
mengunarvalda, svo sem mýkótoxín, málma,
örverur, skordýraeitur, o.fi. Niðurstöður
benda ótvfrætt til, að þörf sé á virku eftirliti
með framleiðsluháttum og innihaldsefnum
náttúrumeðala ekki síður en lyfja, matvæla og
annars sem almenningi býðst til neyslu.
SUMMARY
An evaluation of ginseng products on the
Icelandic market is described. Ginsenosides
were quantitatively determined by HPLC, with
concomitant qualtitative analysis by TLC. Results
showed substantial variation between different
products, both with regard to the content of
individual ginsenosides and the total ginsenoside
concentration. Recommended daily dosages vary
between manufacturers. Results showed that intake
of the manufacturers’ recommended adult daily
dosages would result in daily consumption of total
ginsenosides ranging from practically none at all
to 55 mg. Results of the study emphasize the need
for more stringent and efficient control of herbal
remedies.
HEIMILDIR
1. Der Marderosian A. Natural Product Medicine-
A Scientific Guide to Foods, Drugs, Cosmetics.
Philadelphia: George F. Stickley Co, 1988.
2. The Lawrence Review of Natural Products. Dombek
C, Hulbert MK. Liberti L, eds. St. Louis, Missouri:
JB Lippincott Co, 1990.
3. Kjartansdóttir Þ. Plöntusterar og skyld efni.
Reykjavík: Háskóli Islands (Cand. pharm. ritgerð),
1987.
4. Wichtl M. Teedrogen-Ein Handbuch fiir die
Praxis auf wissenschaftlicher Grundlage. Stuttgart:
Wissenschaftliche Verlagsgesellschaft mbH. 1989.
5. Siegel RK. Ginseng Abuse Syndrome. JAMA 1979:
241 (15): 1614-5.
6. Hopkins MP. Androff L, Benninghoff AS. Ginseng
face cream and unexplained vaginal bleeding. Am J
Obstet Gynecol 1988; 159: 1121-2.
7. Pachaly P. Dunnschichtchromalographie in
der Apotheke. Stuttgart: Wissenschaftliche
Verlagsgesellschaft mbH. 1982; 86.
8. Besso H, Saruwatari Y. Futamura K. Kunihiro
K. Fuwa T. Tanaka O. High performance liquid
chromatographic determination of ginseng saponins
by ultraviolet derivatisation. Planta Medica 1979: 37:
226-33.
9. Schulten HR. Soldati F. Identilication of ginsenosides
from Pana.x ginseng in fractions obtained by
high performance liquid chromatography by field
desorption mass spectroscopy. multiple intemal
refiection infrared spectroscopy and thin layer
chromatography. J Chromatogr 1981; 212: 37-49.
10. Liberti LE, Der Marderosian A. Evaluation of
Commercial Ginscng Products. J Pharm Sci 1978;
67 (10): 1487-9.