Læknablaðið - 15.12.1991, Qupperneq 13

LÆKNABLAÐIÐ
377
SUMMARY
A study was conducted by comparing the
results from 5568 patients from the years
1987 and 1990, which had Chlamydia culture
and Chlamydiazyme@-tests done at the same
time, to assess the feasibility of using different
breakpoints in the Chlamydiazyme®-test for
males and females, or reporting out grey-zones.
Confirmatory tests were done on 247 positive
specimens and calculations were done to assess
the feasibility of doing confirmatory tests on
samples with high but negative values. If the
breakpoint can be lowered by 40 to 50% to 0.060
without significantly decreasing the specificity,
the sensitivity in males will increase to 84% from
just over 70%. Based on this, a decision has been
reached to do confirmatory tests on all specimens
with Chlamydiazyme-values 0.060 or higher.
Results with values above the official cutoff will
be reported as positive if the confirmatory test is
positive. Negative results with values above 0.060
will be reported as suspicious if the Confirmatory
test is positive.
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