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Læknablaðið - 15.03.1994, Blaðsíða 36

Læknablaðið - 15.03.1994, Blaðsíða 36
122 LÆKNABLAÐIÐ calculated for every stage and multivariate analysis used to find independent prognostic factors. Age adjusted incidence for carcinoma of the renal pelvis was 1,1/105 males and 0,4/105 females per year. Comparable figures for ureteral carcinoma were 0,4/105 males and 0,1/105 females, respectively. Most of the patients presented with hematuria and abdominal or flank pain. Of 54 staged patients 28 were stage I-III (54%) and 24 stage IV (46%). Metastasis were found in 22% of the patients, most often in lymph nodes and lungs. Crude five year survival was 44% for the group as a whole, 88% for stage I and 21% for stage IV. Year of diagnosis was not an independent prognostic factor. Carcinomas of the ureter and renal pelvis are uncommon. Incidence in Iceland is relatively low and the clinical presentation similar to neighboring countries. Survival is comparable, in particular for patients with metastasis, but it has not changed for the last two decades. ÞAKKIR Yfirlæknar á skurð- og þvagfæraskurðdeild Borgarspítala, Landakots og FSA fá sérstakar þakkir fyrir veitta aðstoð. Einnig er Helga Sigvaldasyni verkfræðingi, Hrafni Tulinius og öðrum starfsmönnum Krabbameinsskrár Krabbameinsfélags íslands þakkað sérstaklega fyrir þeirra framlag. Vísindasjóður Landspítala og Rannsóknastofu Háskólans, Minningarsjóður Bergþóru Magnúsdóttur og Jakobs J. Bjarnasonar og Vísindasjóður Krabbameinsfélags Islands styrktu rannsóknina. HEIMILDIR 1. Tulinius H, Ragnarsson J. Nýgengi krabbameina á íslandi 1955-1984. Heilbrigðisskýrslur, Reykjavík: Krabbameinsfélagið og landlæknisembættið, 1987. Fylgirit nr. 3: 6. 2. Hvidt V, Feldt-Rassmussen K. Primary tumours in the renal pelvis and ureter with particular attention to the diagnostic problems. Acta Chir Scand 1973; Suppl 433: 91-101. 3. Wagle DG. Moore RH. Murphy GP. Primary carcinoma of the renal pelvis. Cancer 1974; 33: 1642- 8. 4. Guinan P, Vogelzang NJ, Randazzo R. Renal pelvic cancer: A review of 611 patients treated in Ulinois 1975-1985. Urology 1992; 40: 393-9. 5. Grabstald H, Withmore WF. Melmamed MR. Renal pelvic tumors. JAMA 1971: 218: 845-54. 6. Rubenstein MA. Walz BJ, Bucy JG. Transitional cell carcinoma of the kidney: 25 years experiencc. J Urol 1978; 119: 594-7. 7. Nocks B, Heney NH, Daley JJ, et al. Transitional cell carcinoma of the renal pelvis. Urology 1982; 19: 472- 7. 8. Huben RP, Mounzer AM, Murphy GP. Tumor grade and stage as prognostic variables in upper tract urothelial tumors. Cancer 1988; 62: 2016-20. 9. Babaian RJ. Johnson DE. Primary carcinoma of the ureter. J Urol 1980; 123: 357-9. 10. Guðbjartsson T, Einarsson GV. Magnússon J. Nýrnafrumukrabbamein á Islandi 1971-1990: Nýgengi og sjúkdómseinkenni. - Klínísk rannsókn á 408 tilfellum-. Læknablaðið 1994; 80: 13-9. 11. Catalona WJ. Bladder cancer. In: Walsh PC. Retik AB. eds. Campel’s urology, 6. ed. Philadelphia: WB Saunders Comp. 1992: 1094-5. 12. Mostofi FK, Sobing LH, Torloni H, et al. International histological classification of tumours no. 10. Histological typing of urinary bladder tumours. Geneva: WHO, 1973. 13. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Ass 1958; 53: 457-81. 14. Cox DR. Regression models and life tables. J Roy Stat Soc 1972; B34: 187-220. 15. Taron RE. Test for trend in lifetable analysis. Biometrika 1975; 62: 679-82. 16. Parkin DM. Muir CS, Whelan SL. et al. Cancer incidcnce in five continents, Vol. VI. Intemational agency for research on cancer. Lyon: WHO, 1992. 17. Tulinius H. Storm HH. Pukkala E. et al. Cancer in the Nordic Countries, 1981-86. A joint publication of the live Nordic cancer registries, Acta Path Micr Im Scand 1992; 100/Suppl. 31: 95-6. 18. Nprgaard N. Mcllemgaard A. Olsen JH, ct al. Nyrepelvis- og uretertumorer i Danmark 1943-1986. Kræftstatistik nr. 28. Ugeskr Læg 1991; 153: 778-82. 19. Fraley E. Cancer of the renal pelvis. In: Skinner DG. deKernion JB, eds. Genitourinary cancer. Philadelphia: WB Saunders, 1978: 134. 20. McDonald MW, Zincke H. Urothelial tumors of the upper urinary tract. Chapter 1. Genitourinary cancer management. Philadelphia: Lea and Fabinger, 1987: 1-32. 21. McCredie M. Stewart JH. Ford JM. Analgesics and tobacco as risk factors for cancer of the ureter and renal pelvis. J Urol 1983: 130: 281. 22. Petkovic SD. Epidemiology and treatment of renal pelvic and ureteral tumors. J Urol 1975; 114: 858-65. 23. Randovanovic Z. Krajinovic S. Jankovic S, et al. Family history of cancer among cases of upper urothelial tumours in a Balkan nephropathy area. J. Cancer Res Clin Oncol 1985; 110: 181-5.' 24. Anderström C, Johansson SL, Pettersson S, et al. Carcinoma of the ureter: A clinicopathologic study of 49 cases. J Urol 1989; 142: 280-3. 25. Bloom NA. Vidone RA. Lytton B. Primary carcinoma of thc ureter: a report of 102 new cases. J Urol 1970; 103: 590-8. 26. Oldbring J. Glifberg I, Mikulowski P, et al. Carcinoma of the renal pelvis and ureter following bladder carcinoma: Frcquency risk factors and clinicopathological findings. J Urol 1989; 141: 1311- 3. 27. Guðbjartsson T, Einarsson GV, Magnússon J. Nýrnafrumukrabbamein á íslandi 1971-1990: Stigun og lífshorfur. - Klínísk rannsókn á 408 tilfellum-. Læknablaðið 1994; 80: 49-56. 28. Catalona WJ. Urothelial tumors of the renal pelvis and ureter. In: Walsh PC. Retik AB, eds. Campel’s urology 6. ed. Philadelphia: WB Saunders, 1992: 1137-58.

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