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Læknablaðið - 15.02.2010, Síða 26

Læknablaðið - 15.02.2010, Síða 26
F R Æ Ð I G R E I RANNSÓKN N A R 9. Tegnander E, Williams W, Johansen OJ, Blaas HG, Eik-Nes SH. Prenatal detection of heart defects in a non-selected population of 30,149 fetuses - detection rates and outcome. Ultrasound Obstet Gynecol 2006; 27: 252-65. 10. McAuliffe FM, Trines J, Nield LE, Chitayat D, Jaeggi E, Homberger LK. Early fetal echocardiography - a reliable prenatal diagnosis tool. Am J Obstet Gynecol 2005; 193:1253- 59. 11. Li M, Wang W, Yang X, Yan Y, Wu Q. Evaluation of referral indications for fetal echocardiography in beijing. J Ultrasound Med 2008; 27:1291-6. 12. Game E, Stoll C, Clementi M. Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: Experience from 20 european registries. Ultrasound Obstet Gynecol 2001; 17: 386-91. 13. Rychik J, Ayres N, Cuneo B, et al. American society of echocardiography guidelines and standards for performance of the fetal echocardiogram. J Am Soc Echocardiogr 2004; 17: 803-10. 14. Simpson LL. Indications for fetal echocardiography from a tertiary-care obstetric sonography practice. J Clin Ultrasound 2004; 32:123-8. 15. Cooper MJ, Enderlein MA, Dyson DC, Roge CL, Tamoff H. Fetal echocardiography: Retrospective review of clinical experience and an evaluation of indications. Obstet Gynecol 1995; 86: 577-82. 16. Perri T, Cohen-Sacher B, Hod M, Berant M, Meizner I, Bar J. Risk factors for cardiac malformations detected by fetal echocardiography in a tertiary center. J Matem Fetal Neonatal Med 2005; 17:123-8. 17. Macintosh MC, Fleming KM, Bailey JA, et al. Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in england, wales, and northem ireland: Population based study. BMJ 2006; 333:177. 18. Friedberg MK, Silvermann NH. Changing indications for fetal echocardiography in a University Center population. Prenat Diagn 2004; 24: 781-6. 19. Bahado-Singh RO, Wapner R, Thom E, et al. Elevated first- trimester nuchal translucency increases the risk of congenital heart defects. Am J Obstet Gynecol 2005; 192:1357-61. 20. Makrydimas G, Sotiriadis A, Huggon IC, et al. Nuchal translucency and fetal cardiac defects: A pooled analysis of major fetal echocardiography centers. Am J Obstet Gynecol 2005; 192: 89-95. 21. McAuliffe FM, Homberger LK, Winsor S, Chitayat D, Chong K, Johnson JA. Fetal cardiac defects and increased nuchal translucency thickness: A prospective study. Am J Obstet Gynecol 2004; 191:1486-90. 22. Makrydimas G, Sotiriadis A, Ioannidis JP. Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis. Am J Obstet Gynecol 2003; 189:1330-5. 23. Moore JW, Binder GA, Berry R. Prenatal diagnosis of aneuploidy and deletion 22qll.2 in fetuses with ultrasound detection of cardiac defects. Am J Obstet Gynecol 2004; 191: 2068-73. i Fetal Echocardiography in lceland 2003-2007; indications and outcomes >- cc < 2 2 3 V) X (0 -I C3 z Lli Objective: The aim of the study was to evaluate the indications and outcomes of fetal echo (FE) and determine which indication has the highest detection rate for congenital heart disease (CHD). Methods: The referral indications and results of FE performed in lceland during 2003-2007 were reviewed. Information regarding gestational age at diagnosis, nuchal translucency, pregnancy outcome, autopsy results and postnatal diagnosis were obtained from medical records. Results During the five year period 1187 FE were performed. Structural heart defect was diagnosed in 73 fetuses. The most common referral indication was family history of CHD (631;53.2%) which led to diagnosis of 18 heart defects prenatally (2.9%). The second most common referral indication was increased nuchal translucency (159) and abnormal cardiac findings were present in 16 cases (10.1 %). A total of 30 women were referred for FE because of abnormal four chamber view (AFCV) which resulted in the diagnosis of 22 (73.3%) major heart defects, either incompatible with life or requiring immediate intervention after birth. Other indications led mostly to the diagnoses of minor defects. Conclusions: AFCV is the most important predictor for diagnosis of structural heart defects. 2,5% were referred for FE due to AFCV which led to diagnosis of 30% of all heart defects, all of which were major. Thorisdottir S, Hardardottir H, Hjartardottir H, Oskarsson G, Helgason H, Sigfusson G. Fetal Echocardiography in lceland 2003-2007; indications and outcomes lcel Med J 2010; 93-8 Key words: fetal echocardiography, indications, congenital heart disease. Correspondence: Hildur Harðardóttir, hhard@iandspitaii.is 98 LÆKNAblaðið 2010/96 Barst: 30. júní 2009, - samþykkt til birtingar: 4. desember 2009 Hagsmunatengsl: Engin

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