Læknablaðið - 15.10.1990, Page 44

410
LÆKNABLAÐIÐ
talsverðan hluta mælinganna. Þeim og öðru
starfsfólki sónardeildar og göngudeildar
Kvennadeildar er þakkað. Aðstaða fékkst fyrir
úrvinnslu á kvennadeild og upplýsinga- og
tölvudeild Almenna sjúkrahússins í Malmö,
Svfþjóð.
Evrópuráðið (Fellowship fyrir Reyni T.
Geirsson númer 86.066) og Vísindasjóður
Landspítalans styrktu rannsóknina.
SUMMARY
To describe pattems and limits of intrauterine
growth in the Icelandic population a longitudinal
ultrasound study was carried out in 94 healthy
women, all with regular 28±2day cycles and able
to securely date the first 'day of their last menstrual
period. A total of 3795 measurements, with a
mean of eight per woman, were obtained every
three weeks during the second and third trimester.
Biparietal, occipitofrontal, abdominal transverse
and anteroposterior diameters (combined into mean
abdominal diameter), as well as femur and humerus
length were measured. The data were computerised
and grouped into 12 two-week periods for each of
which the mean examination day was calculated.
Multiple regression analysis was applied to fit
the data to mathematical equations. Third degree
polynomials showed optimal fit to the bone
measurements, but second degree to the abdominal
measures. The equations gave values for the bone
measurements very similar to those previously
described from other Nordic countries, but because
of larger size of the material and less accurate
cycle dating, the dispersion of values was larger.
Mean abdominal values were systematically about
7% lower, which probably was due to differences
in measurement technique. This must be accounted
for by use of an appropriate correction factor when
the measurements are used to estimate fetal weight.
Comparative data on fetal growth in the Nordic
countries and nomograms for growth of Icelandic
fetuses are presented.
HEIMILDIR
1. Grennert L, Persson P-H, Gennser G. Benefits of
ultrasonic screening of a pregnant population. Acta
Obstet Gynecol Scand 1978; Suppl 78: 5-14.
2. Geirsson RT, Persson P-H. Diagnosis of intrauterine
growth retardation using ultrasound. Clin Obstet
Gynecol 1984; 11: 457-80.
3. Persson P-H. Fetal growth curves. In: Sharp F, Milner
RDG. Fraser RB, eds. Fetal growth. London: Royal
College of Obstetricians and Gynaecologists, 1989:
13-25.
4. Campbell S, Newman GB. Growth of the fetal
biparietal diameter during normal pregnancy. J Obstet
Gynaecol Br Commonw 1971; 78: 513-9.
5. Hansmann M, Hackelöer BJ, Staudach A.
Ultraschalldiagnostik in Geburtshilfe und
Gynakologie. Berlin: Springer Verlag, 1985.
6. Persson P-H, Weldner B-M. Normal range growth
curves for fetal biparietal diameter, occipitofrontal
diameter, mean abdominal diameters and femur
length. Acta Obstet Gynecol Scand 1986; 65: 759-61.
7. Chervenak FA, Jeanty P, Hobbins JC. Current status
of fetal age and growth assessment. Clin Obstet
Gynaecol 1983; 10: 423-44.
8. Biering G, Snædal G, Sigvaldason H, Ragnarsson J,
Geirsson RT. Size at birth in Iceland. Acta Paediatr
Scand 1985; Suppl. 319: 68-73.
9. Parker AJ, Davies P, Newton JR. Assessment of
gestational age of the Asian fetus by the sonar
measurement of crown-rump length and biparietal
diameter. Br J Obstet Gynaecol 1982; 89: 836-8.
10. Hytten FE, Altman DG. Intrauterine growth
retardation: Let’s be clear about it. Br J Obstet
Gynaecol 1989; 96: 1127-8.
11. Oldham PD. Measurement in medicine. London: The
English Universities Press, 1968.
12. Sindberg Eriksen P, Secher NJ, Weis-Bentzon M.
Normal growth of the fetal biparietal diameter and
the abdominal diameter in a longitudinal study. Acta
Obstet Gynecol Scand 1985; 64: 65-70.
13. Yagel S, Adoni A, Oman S, Wax Y, Hochner-
Celnikier. A statistical examination of the accuracy
of combining femoral length and biparietal diameter
as an index of fetal gestational age. Br J Obstet
Gynaecol 1986; 93: 109-15.
14. Goldstein H. The design and analysis of longitudinal
studies. London: Academic Press, 1979.
15. Geirsson RT. Leiðbeiningar um ómskoðun í
meðgöngu. Fréttabréf læknaA-æknablaðið 1987; 3:
12-3.
16. Steingrímsdóttir Þ, Geirsson RT, Kristjánsdóttir B.
Breytingar á legbotnshæð í meðgöngu hjá íslenskum
konum. Læknablaðið 1987; 73: 369-74.
17. Sveinsdóttir G, Ólafsdóttir S, Geirsson RT. Reykingar
íslenskra kvenna á meðgöngu. Læknablaðið 1990; 76:
111-5.