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Læknablaðið - 15.10.1990, Qupperneq 44

Læknablaðið - 15.10.1990, Qupperneq 44
410 LÆKNABLAÐIÐ talsverðan hluta mælinganna. Þeim og öðru starfsfólki sónardeildar og göngudeildar Kvennadeildar er þakkað. Aðstaða fékkst fyrir úrvinnslu á kvennadeild og upplýsinga- og tölvudeild Almenna sjúkrahússins í Malmö, Svfþjóð. Evrópuráðið (Fellowship fyrir Reyni T. Geirsson númer 86.066) og Vísindasjóður Landspítalans styrktu rannsóknina. SUMMARY To describe pattems and limits of intrauterine growth in the Icelandic population a longitudinal ultrasound study was carried out in 94 healthy women, all with regular 28±2day cycles and able to securely date the first 'day of their last menstrual period. A total of 3795 measurements, with a mean of eight per woman, were obtained every three weeks during the second and third trimester. Biparietal, occipitofrontal, abdominal transverse and anteroposterior diameters (combined into mean abdominal diameter), as well as femur and humerus length were measured. The data were computerised and grouped into 12 two-week periods for each of which the mean examination day was calculated. Multiple regression analysis was applied to fit the data to mathematical equations. Third degree polynomials showed optimal fit to the bone measurements, but second degree to the abdominal measures. The equations gave values for the bone measurements very similar to those previously described from other Nordic countries, but because of larger size of the material and less accurate cycle dating, the dispersion of values was larger. Mean abdominal values were systematically about 7% lower, which probably was due to differences in measurement technique. This must be accounted for by use of an appropriate correction factor when the measurements are used to estimate fetal weight. Comparative data on fetal growth in the Nordic countries and nomograms for growth of Icelandic fetuses are presented. HEIMILDIR 1. Grennert L, Persson P-H, Gennser G. Benefits of ultrasonic screening of a pregnant population. Acta Obstet Gynecol Scand 1978; Suppl 78: 5-14. 2. Geirsson RT, Persson P-H. Diagnosis of intrauterine growth retardation using ultrasound. Clin Obstet Gynecol 1984; 11: 457-80. 3. Persson P-H. Fetal growth curves. In: Sharp F, Milner RDG. Fraser RB, eds. Fetal growth. London: Royal College of Obstetricians and Gynaecologists, 1989: 13-25. 4. Campbell S, Newman GB. Growth of the fetal biparietal diameter during normal pregnancy. J Obstet Gynaecol Br Commonw 1971; 78: 513-9. 5. Hansmann M, Hackelöer BJ, Staudach A. Ultraschalldiagnostik in Geburtshilfe und Gynakologie. Berlin: Springer Verlag, 1985. 6. Persson P-H, Weldner B-M. Normal range growth curves for fetal biparietal diameter, occipitofrontal diameter, mean abdominal diameters and femur length. Acta Obstet Gynecol Scand 1986; 65: 759-61. 7. Chervenak FA, Jeanty P, Hobbins JC. Current status of fetal age and growth assessment. Clin Obstet Gynaecol 1983; 10: 423-44. 8. Biering G, Snædal G, Sigvaldason H, Ragnarsson J, Geirsson RT. Size at birth in Iceland. Acta Paediatr Scand 1985; Suppl. 319: 68-73. 9. Parker AJ, Davies P, Newton JR. Assessment of gestational age of the Asian fetus by the sonar measurement of crown-rump length and biparietal diameter. Br J Obstet Gynaecol 1982; 89: 836-8. 10. Hytten FE, Altman DG. Intrauterine growth retardation: Let’s be clear about it. Br J Obstet Gynaecol 1989; 96: 1127-8. 11. Oldham PD. Measurement in medicine. London: The English Universities Press, 1968. 12. Sindberg Eriksen P, Secher NJ, Weis-Bentzon M. Normal growth of the fetal biparietal diameter and the abdominal diameter in a longitudinal study. Acta Obstet Gynecol Scand 1985; 64: 65-70. 13. Yagel S, Adoni A, Oman S, Wax Y, Hochner- Celnikier. A statistical examination of the accuracy of combining femoral length and biparietal diameter as an index of fetal gestational age. Br J Obstet Gynaecol 1986; 93: 109-15. 14. Goldstein H. The design and analysis of longitudinal studies. London: Academic Press, 1979. 15. Geirsson RT. Leiðbeiningar um ómskoðun í meðgöngu. Fréttabréf læknaA-æknablaðið 1987; 3: 12-3. 16. Steingrímsdóttir Þ, Geirsson RT, Kristjánsdóttir B. Breytingar á legbotnshæð í meðgöngu hjá íslenskum konum. Læknablaðið 1987; 73: 369-74. 17. Sveinsdóttir G, Ólafsdóttir S, Geirsson RT. Reykingar íslenskra kvenna á meðgöngu. Læknablaðið 1990; 76: 111-5.
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