Læknablaðið - 01.10.2015, Blaðsíða 27

LÆKNAblaðið 2015/101 467
Y F I R L I T S G R E I N
Heimildir
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Samantekt
Frumkímfrumur eru forverar kynfruma og mynda hinn ævarandi
hlekk á milli kynslóða lífvera.
Torvelt hefur verið að rannsaka þroskun frumkímfruma
manna vegna þess hversu óaðgengilegar þær eru á fósturþroska.
Nú hefur tekist að sérhæfa frumkímfrumur manna með því að
nota fjölhæfar fósturvísastofnfrumur og iPS-frumur sem upp-
hafsfrumur í rækt. Því eru miklar vonir bundnar við að á næstu
árum verði mögulegt að herma eftir öllum stigum kynfrumu-
þroska manna í vefjarækt, og þar með skapa grundvöll rannsókna
á ófrjósemi og sjúkdómum tengdum þroskun kímfruma. Þannig
eru líka bundnar vonir við að ræktun frumkímfruma geti valdið
frekari framförum við þróun hjálparaðferða við frjóvgun og að
unnt verði að nota ræktarkerfið til þess að varðveita frjósemi fólks
eftir krabbameinsmeðferð.
Þakkir
Ég vil þakka Guðrúnu Valdimarsdóttur, Eiríki Steingrímssyni og
Pétri Henry Petersen fyrir yfirlestur handrits og góðar athuga-
semdir og umræður.