Læknablaðið - 15.02.1990, Side 38

110
LÆKNABLAÐIÐ
anticoagulant therapy, whereof 147 continued for 3
months or more. Those 147 patients, 90 men and
57 women, mean age 62 years, made up our study
group.
The main indications for therapy were; »deep vein
thrombophlebitis«, »coronary artery bypass graft«,
»atrial fibrillation«, »pulmonary embolism« and
»artificial heart valves«.
Bleeding complications were found with 9 patients
(6,1%) thereof 2 (1,4%) had serious episodes.
Recurrences of indicative problem occurred with 7
patients (4,8%), 4 (2,8%) while on treatment.
Those results are comparable to those of studies of
similar design from other countries.
In conclusion we state that the long term
anticoagulant therapy is effective and without
undue high rate of complications at the General
District Hospital of Akureyri. Changes in treatment
regimen are therefore not recommended without
further prospective studies.
HEIMILDIR
1. Levine MN. Nonhemorrhagic complications of
anticoagulant therapy. 1: Seminars in thrombosis and
hemostasis 1986; 12: 63-6.
2. Levine MN, Raskob G, Hirsh J. Risk of haemorrhage
associated with long term anticoagulant therapy.
Drugs 1985; 30: 444-60.
3. Hirsh J, I-evine MN. The optimal intensity of oral
anticoagulant therapy. JAMA 1987; 258: 2723-6.
4. Nitter-Hauge S, Dale J. High complication and failiire
rates of anticoagulant therapy are unavoidable. Z
Kardiol 1986; 75: 293-7.
5. Broekmans AW, Loeliger EA. High complication and
failure rates of anticoagulant therapy are avoidable. Z
Kardiol 1986; 75: 298-301.
6. Ceriani P, Cavalli P, Perone C. Complicanze
chirurgiche della terapia anticoagulante. Minerva
chirurgica 1985; 40: 1361-4.
7. Svensson J, Blombáck M, Kockum C. Hög
frekvens af blödningskomplikationer vid
antikoagulationsbehandling. Lákartidningen 1985; 82:
1240-4.
8. Levine MN, Raskob G, Hirsh J. Hemorrhagic
complications of long term anticoagulant therapy.
Chest 1986; 89: 16-25.
9. Geirsson O. Eftirlit með Dicumarol-meðferð.
Læknablaðið 1960; 60: 134-41.
10. Snorrason SP. Lyflækningadeild Landspítala -
persónulegar upplýsingar.
11. Skúlason T. Segavamir gegn kransæðasjúkdómum.
Læknablaðið 1960; 60: 123-33.
12. Howard MR, Milligan DW. Frequency of attendance
at anticoagulant clinics: a prospective study. Br Med
J 1988: 296: 898-9.
13. Editorial. Management of venous thromboembolism.
Lancet 1988; 275-7.