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Læknablaðið - 15.04.1993, Page 27

Læknablaðið - 15.04.1993, Page 27
LÆKNABLAÐIÐ 155 sýklalyfjum. Um 25% sjúklinganna lagast þó af sjálfu sér án meðferðar líkt og sést við bráða eyrnabólgu. Rannsóknir og reynsla benda einnig til þess, að meðhöndla þurfi með sýklalyfjum í að minnsta kosti 14 daga til að fullkomin lækning náist. Sumar rannsóknir hafa dregið í efa nauðsyn þess að meðhöndla skútabólgu með sýklalyfjum (39-41). Sjúklingar í þessum rannsóknum voru meðhöndlaðir í 10 daga með sýklalyfjum sem í mörgum tilfellum voru ekki virk gegn bakteríum þeim sem ræktaðar voru frá skútunum. Aðferðarfræði þessara rannsókna var einnig í mörgu öðru ábótavant og rýra þessi atriði niðurstöður þeirra verulega. Val sýklalyfja og meðferðarlengd fer eftir því, hversu lengi sjúkdómseinkennin hafa staðið og hvaða bakteríur eru líklegir sjúkdómsvaldar. Gagnsemi annarra lyfja hefur hins vegar ekki verið rannsökuð til fulls. I fáum tilfellum er skurðaðgerð nauðsynleg. HEIMILDIR 1. Wald ER. Milmoe GJ, Bowen A, Medina JL, Salamon N, Bluestone CD. Acute maxillary sinusitis in children. N Engl J Med 1981; 304: 749-54. 2. Wald ER, Guerra N, Byers C. Upper respiratory tract infections in young children; duration of and frequency of complications. Pediatrics 1991; 87: 129- 33. 3. Goldenhersh MJ, Rachelefsky GS. Sinusitis: Early recognition, aggressive treatment. Contemp Pediatr 1989; 6: 22-42. 4. Glasier CM, Mallory GB, Steele RW. Significance of opacification of the maxillary and ethmoid sinuses in infants. J Pediatr 1989; 114; 45-50. 5. Bluestone CD. The diagnosis and management of sinusitis in children: proceedings of a closed conference. Pediatr Infect Dis 1985; 6/Suppl.: 49-81. 6. Dingle JH, Badjer DF, Jordan WS Jr. Pattems of Illness: Illness in the Home. Cleveland, OH: Westem Reserve University, 1964: 347. 7. Wald ER. Epidemiology, pathophysiology and etiology of sinusitis. Pediatr Infect Dis 1985; 4/Suppl. 6: 51-4. 8. Carson JL, Collier AM, Hu S. Aquired ciliary defects in nasal epithelium of children with acute viral upper respiratory infections. N Engl J Med 1985; 312: 463- 8. 9. Rachelefsky GS, Goldberg M, Katz RM. Sinus disease in children with respiratory allergy. Allergy Clin Immunol 1978; 61: 310-4. 10. Shapiro GG. Role of allergy in sinusitis. Pediatr Infect Dis J 1985; 4: 55-8. 11. Shapiro GG, Virant FS, Fumkawa CT, Pierson WE, Bierman W. Immunologic defects in patients with refractory sinusitis. Pediatrics 1991; 87: 311-6. 12. Evans FO Jr, Sydnor JB, Moore WEC, et al. Sinusitis of the maxillary antmm. N Engl J Med 1975; 293: 735-9. 13. Wald ER, Reilly JS, Casselbrant M, et al. Treatment of acute maxillary sinusitis in childhood: a comparative study of amoxicillin and cefaclor. J Pediatr 1984; 104: 297-302. 14. Siegel JD. Diagnosis and management of acute sinusitis in children. Pediatr Infect Dis J. 1987; 6: 95-9. 15. Tinkelman DG, Silk HJ. Clinical and bacteriologic features of chronic sinusitis in children. Am J Dis Child 1989; 143: 938-41. 16. Brook I. Bacteriologic features of chronic sinusitis in children. JAMA 1981; 246: 967-9. 17. Wald ER. Diagnostic considerations. Pediatr Infect Dis J 1985; 4/Suppl. 6: 61-4. 18. Wald ER. Management of sinusitis in infants and children. Pediatr Infect Dis J 1988; 7: 449-52. 19. Meresh MM. Washbum AH. Paranasal sinuses from birth to late adolescence. Am J Dis Child 1940; 60: 841-61. 20. Rachelefsky GS, Katz RM, Siegel SC. Chronic sinusitis in children with respiratory allergy: the role of antimicrobials. J Allergy Clin Immunol 1982; 69: 382-7. 21. Rachelefsky GS. Chronic sinusitis. Am J Dis Child 1989; 143: 886-8. 22. Rachelefsky GS, Katz. RM, Siegel SC. Chronic sinus disease with associated reactive airway disease in children. Pediatrics 1984; 73: 526-9. 23. Slavin RG. Relationship of nasal disease and sinusitis to bronchial asthma. Annals of Allery 1982; 49: 76- 80. 24. Arrnda LK, Mimca IM, Solé D, et al. Abnormal maxillary sinus radiographs in children: Do they represent bacterial infection? Pediatrics 1990; 85: 553-8. 25. Kaatee R, Guðnason Þ, Brekkan Á. Utility of radiographs in children with clinical infection of the paranasal sinuses. Erindi á X. þingi Félags íslenskra lyflækna á Egilsstöðum 12.-14. júní 1992. 26. Glasier CM, Ascher DP, Williams KM. Incidental paranasal sinus abnormalities on CT of children: clinical correlation. AJR 1986; 7: 861-4. 27. Shopfner CE, Rossi JO. Roentgen evaluation of the paranasal sinuses in children. AJR 1973; 118: 176-86. 28. Kovatch AL, Wald ER, Ledesma-Medina J, Chiponis DM, Bedingfield B. Maxillary sinus radiographs in children with nonrespiratory complaints. Pediatrics 1984; 73: 306-8. 29. Rachelefsky GS, Shapiro GG. Diseases of the paranasal sinuses in children. In: Bierman CW, Pearlman DS, eds. Allergic Disorders of Infancy, Childhood and Adolescence. Philadelphia: WB Saunders; 1980: 526-34. 30. Hamory BH, Sande MA, Sydnor A, Seale DL, Gwaltney JM. Etiology and antimicrobial therapy of acute maxillary sinusitis. J Infect Dis 1979; 139: 197-202. 31. Wald ER, Chiponis D, Ledesma-Medina J. Comparative effectiveness of amoxicillin and amoxicillin-clavulanate potassium in acute paranasal sinus infection in children: A double-blind, placebo- controlled trial. Pediatrics 1986; 77: 795-800. 32. Wald ER. Medical management: a pediatrician’s perspective. Pediatr Infect Dis J 1985; 4/Suppl.6: 65- 6. 33. Kristinsson K, Pétursdóttir O. Sýklalyfjanæmi Hemophilus influenzae á Islandi. Obirtar niðurstöður. 34. Aust R, Drettner B, Falck B. Studies of the effect of peroral fenylpropanolamin on the functional size of

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