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Læknablaðið - 15.04.1994, Blaðsíða 17

Læknablaðið - 15.04.1994, Blaðsíða 17
LÆKNABLAÐIÐ 139 had developed AIDS. Twelve HlV-positive patients were examined at the Department of Ophthalmology, nine of whom had ocular complications (8 of 9 had AIDS). Four had died by september 30th 1993 (all with cytomegalovirus retinitis). Six patients had cytomegalovirus retinitis, one had optic nerve atrophy, one had chronic herpes simplex keratitis and six had retinal microvasculopathy (in one case the only ocular complication). Survival after diagnosis of cytomegalovirus retinitis was 2, 10, 12.5 and 14 months. Two patients became blind (<3/60 on better eye). Two patients developed retinal detachments which was repaired in one of them. Ocular complications of AIDS can cause a serious handicap in otherwise relatively healthy AIDS patients. As immunodeficient patients will survive longer with better treatment against the HIV- infection, ocular complications will make increased demand on ophthalmological and other medical services. ÞAKKIR Eftirtöldum læknum færum við bestu þakkir fyrir aðstoð og aðgang að sjúkraskrám: Haraldi Sigurðssyni, Kristjáni Erlendssyni, Sigurði Guðmundssyni, Sigurði B. Þorsteinssyni og Þórði Sverrissyni. HEIMILDIR 1. Jabs DA, Green WR, Fox R, Polk BF, Bartlett JG. Ocular manifestations of acquired immune deficiency syndrome. Ophthalmology 1989; 96: 1092-9. 2. Holland GN. Acquired immunodeficiency syndrome and ophthalmology: the first decade. Am J Ophthalmol 1992; 114: 86-95. 3. Engstrom RE, Holland GN, Hardy WD, Meiselman HJ. Hemorheologic abnormalities in patients with human immunodeficiency virus infection and ophthalmic microvasculopathy. Am J Ophthalmol 1990; 109: 153-61. 4. Bloom JN, Palestine AG. The diagnosis of cytomegalovirus retinitis. Ann Int Med 1988; 109: 963-9. 5. Studies of Ocular Complications of AIDS (SOCA) research group in collaboration with the AIDS Clinical Trial Group (ACTG): Mortality in patients with the acquired immunodeficiency syndrome treated with either Foscamet or Ganciclovir for Cytomegalovirus retinitis. N Engl J Med 1992; 326: 213-20. 6. Jabs DA, Enger C, Haller J, de Bustros S. Retinal detachments in patients with cytomegalovirus retinitis. Arch Ophthalmol 1991; 109: 794-9. 7. Sidikaro Y, Silver L, Holland GN, Kreiger AE. Rhegmatogenous retinal detachments in patients with AIDS and necrotizing retinal infections. Ophthalmology 1991; 98: 129-35. 8. Freeman WR, Quiceno JI, Crapotta JA, Listhaus A, Munguia D, Aguilar MF. Surgical repair of rhegmatogenous retinal detachment in immunosuppressed patients with cytomegalovims retinitis. Ophthalmology 1992; 99: 466-74. 9. Young TL, Robin JB, Holland GN, et al. Herpes simplex keratitis in patients with acquired immune deticiency syndrome. Ophthalmology 1989; 96: 1476- 9. 10. Friedman DI. Neuro-ophthalmic manifestations of human immunodeficiency vims infection. Neurol Clin 1991; 9: 55-68. 11. Keane JR. Neuro-ophthalmologic signs of AIDS: 50 patients. Neurology 1991; 41: 841-5. 12. Quiceno JI, Capparelli E, Sadun AA, et al. Visual dysfunction without retinitis in patients with acquired immunodeficiency syndrome. Am J Ophthalmol 1992; 113: 8-13. 13. Tenhula WN, Xu S, Madigan MC, Heller K, Freeman WR, Sadun AA. Morphometric comparisons of optic nerve axon loss in acquired immunodeficiency syndrome. Am J Ophthalmol 1992; 113: 14-20. 14. Newman NJ, Lessell S. Bilateral optic neuropathies with remission in two HlV-positive men. J Clin Neuro-Ophthalmol 1992; 12: 1-5. 15. Culbertsson WW. Infections of the retina in AIDS. Int Ophthalinol Clin 1989; 29: 108. Cited in Holland GN (2).

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